TRPC5 Polyclonal Antibody | Invitrogen OST00054G product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

TRPC5 Polyclonal Antibody

catalog :

OST00054G

quantity :

500 µg

price :

US 425

clonality :

polyclonal

host :

domestic sheep

conjugate :

nonconjugated

reactivity :

human

application :

western blot, immunohistochemistry

citations: 1

Published Application/Species/Sample/Dilution	Reference
western blot; human; loading ...; fig s10a	Maeda K, Otomo K, Yoshida N, Abu Asab M, Ichinose K, Nishino T, et al. CaMK4 compromises podocyte function in autoimmune and nonautoimmune kidney disease. J Clin Invest. 2018;128:3445-3459 pubmed publisher

product information

Product Type :

Antibody

Product Name :

TRPC5 Polyclonal Antibody

Catalog # :

OST00054G

Quantity :

500 µg

Price :

US 425

Clonality :

Polyclonal

Purity :

Ammonium sulfate precipitation

Host :

Sheep

Reactivity :

Human

Applications :

Immunohistochemistry: 10-50 µg/mL, Western Blot: 10-50 µg/mL

Species :

Human

Isotype :

IgG

Storage :

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability.

Description :

TRPC5 belongs to the transient receptor family. TRPC5 is one of the seven mammalian TRPC (transient receptor potential channel) proteins. The TRPC5 protein is a multi-pass membrane protein and is thought to form a receptor-activated non-selective calcium permeant cation channel. TRPC5 is active alone or as a heteromultimeric assembly with TRPC1, TRPC3, and TRPC4. TRPC5 also interacts with multiple proteins including calmodulin, CABP1, enkurin, Na(+)-H+ exchange regulatory factor (NHERF ), interferon-induced GTP-binding protein (MX1), ring finger protein 24 (RNF24), and SEC14 domain and spectrin repeat-containing protein 1 (SESTD1). TRPC5 is thought to form a receptor-activated non-selective calcium permeant cation channel. TRPC5 is probably operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases, or G-protein coupled receptors. TRPC5 has also been shown to be calcium-selective, and may also be activated by intracellular calcium store depletion. Diseases associated with TRPC5 include Hypertrophic Pyloric Stenosis and Pyloric Stenosis.

Immunogen :

A synthetic peptide from 4th cytoplasmic domain of human TRPC5 (TRP5) conjugated to an immunogenic carrier protein was used as the immunogen.

Format :

Lyophilized

Applications w/Dilutions :

Immunohistochemistry: 10-50 µg/mL, Western Blot: 10-50 µg/mL

Aliases :

capacitative calcium entry channel 2; CCE2; hTRP5; Htrp-5; mtrp5; PPP1R159; protein phosphatase 1, regulatory subunit 159; short transient receptor potential channel 5; short transient receptor potential channel 5a; transient receptor potential cation channel, subfamily C, member 5a; transient receptor potential cation channel subfamily C member 5; transient receptor potential cation channel subfamily c member 5a; transient receptor potential cation channel, subfamily C, member 5; transient receptor potential cation channel, subfamily C, member 5a; transient receptor potential channel 5; transient receptor protein 5; TRP5; TRP-5; TrpC5; trpc5a; trp-related protein 5; Trrp5; vtransient receptor potential cation channel, subfamily C, member 5; wu:fi73f08