TRPV4 Polyclonal Antibody | Invitrogen OSR00136W product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

TRPV4 Polyclonal Antibody

catalog :

OSR00136W

quantity :

100 µL

price :

US 450

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry

citations: 1

Reference
Ducza E, Csányi A, Szoke E, Pohoczky K, Hajagos Tóth J, Kothencz A, et al. Significance of transient receptor potential vanilloid 4 and aquaporin 5 co-expression in the rat uterus at term. Heliyon. 2019;5:e02697 pubmed publisher

product information

Product Type :

Antibody

Product Name :

TRPV4 Polyclonal Antibody

Catalog # :

OSR00136W

Quantity :

100 µL

Price :

US 450

Clonality :

Polyclonal

Host :

Rabbit

Reactivity :

Human, Mouse, Non-human primate, Rat

Applications :

Immunohistochemistry: 1:300-1:2000, Western Blot: 1:300-1:2000

Species :

Human, Mouse, Non-human primate, Rat

Isotype :

IgG

Storage :

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability.

Description :

TRPV4 (Transient Receptor Potential Cation Channel Subfamily V Member 4) is a cation-selective channel, activated in response to systemic osmotic pressure. Non-selective calcium permeant cation channel probably involved in osmotic sensitivity and mechanosensitivity. TRPV4 is a member of the OSM9-like transient receptor potential channel (OTRPC) subfamily in the transient receptor potential (TRP) superfamily of ion channels. The TRPV4 protein is a Ca2+-permeable, nonselective cation channel that is thought to be involved in the regulation of systemic osmotic pressure. Mutations in the TRPV4 gene are the cause of spondylometaphyseal and metatropic dysplasia and hereditary motor and sensory neuropathy type IIC. Diseases associated with TRPV4 include Metatropic Dysplasia and Spondylometaphyseal Dysplasia, Kozlowski Type. Multiple transcript variants encoding different isoforms have been found for this gene.

Immunogen :

A synthetic peptide from aa region 300-400 of mouse TRPV4 conjugated to blue carrier protein was used as the antigen.

Format :

Lyophilized

Applications w/Dilutions :

Immunohistochemistry: 1:300-1:2000, Western Blot: 1:300-1:2000

Aliases :

0610033B08Rik; BCYM3; CMT2C; HMSN2C; OSM9-like transient receptor potential channel 4; Osm-9-like TRP channel 4; osmosensitive transient receptor potential channel 4; Otrpc4; SMAL; SPSMA; SSQTL1; Transient receptor potential cation channel subfamily V member 4; transient receptor potential cation channel, subfamily 5, member 4; transient receptor potential cation channel, subfamily V, member 4; transient receptor potential protein 12; Trp12; TrpV4; trpv4 channel; Vanilloi; vanilloid receptor-like channel 2; Vanilloid receptor-like protein 2; vanilloid receptor-related osmotically activated channel; vanilloid receptor-related osmotically activated channel (Vroac); vanilloid receptor-related osmotically-activated channel; Vrl2; VRL-2; Vroac; VR-OAC; wu:fp52e02