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antibody

Rho Pan Polyclonal Antibody

OSC00025W

100 µL

US 425

polyclonal

domestic rabbit

nonconjugated

human, mouse, rat

western blot, immunohistochemistry

Rho Pan Polyclonal Antibody

OSC00025W

100 µL

US 425

Polyclonal

Rabbit

Human, Mouse, Rat

Immunohistochemistry: 1:300-1:2,000, Western Blot: 1:300-1:2,000

Human, Mouse, Rat

IgG

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability.

This gene encodes a member of the Rho family of small GTPases, which cycle between inactive GDP-bound and active GTP-bound states and function as molecular switches in signal transduction cascades. Rho proteins promote reorganization of the actin cytoskeleton and regulate cell shape, attachment, and motility. The protein encoded by this gene is prenylated at its C-terminus, and localizes to the cytoplasm and plasma membrane. It is thought to be important in cell locomotion. Overexpression of this gene is associated with tumor cell proliferation and metastasis. Multiple alternatively spliced variants, encoding the same protein, have been identified.

A synthetic peptide from human Rho-related GTP-binding proteins (RhOA, RhOB, RhOC, RhOF, RhOQ) and RAC1, RAC2, RAC3 and CDC42 conjugated to blue carrier protein was used as the antigen.

Lyophilized

Immunohistochemistry: 1:300-1:2,000, Western Blot: 1:300-1:2,000

AA017882; AI324259; AI845056; Aplysia ras-related homolog 12; Aplysia RAS-related homolog 6; aplysia ras-related homolog 9 (RhoC); aplysia ras-related homolog A; aplysia ras-related homolog A1; aplysia ras-related homolog A2; aplysia ras-related homolog B; ARH12; ARH6; ARH9; ARHA; Arha1; Arha2; Arhb; ARHC; ARHF; ARHQ; AV026554; epididymis secretory protein Li 42; h12; h6; H9; HEL-S-42; Ifld1; induced in fatty liver dystrophy 1; MST081; MSTP081; oncogene RHO H12; oncogene RHO H6; oncogene RHO H9; plysia ras-related homolog A2; Ras family member A; ras homolog 9 (RhoC); ras homolog A1; ras homolog A2; ras homolog B; ras homolog family member A; ras homolog family member B; ras homolog family member C; ras homolog family member F (in filopodia); ras homolog family member F, filopodia associated; ras homolog family member Q; ras homolog gene family, member A; ras homolog gene family, member A1; ras homolog gene family, member A2; ras homolog gene family, member AB; ras homolog gene family, member B; ras homolog gene family, member C; ras homolog gene family, member f; ras homolog gene family, member F (in filopodia); ras homolog gene family, member Q; RASL7A; ras-like protein family member 7A; Ras-like protein TC10; RAS-like, family 7, member A; ras-related GTP-binding protein TC10; RAS-related homolog 9; Rho cDNA clone 12; Rho cDNA clone 6; rho cDNA clone 9; rho family; Rho family GTPase; rho family GTPase Rif; Rho in filopodia; RHO12; Rhoa; Rhob; RHOC; rhoC GTPase; RHOF; RHOH12; RHOH6; RHOH9; Rhoq; rho-related GTP-binding protein RhoB; Rho-related GTP-binding protein RhoC; rho-related GTP-binding protein RhoF; Rho-related GTP-binding protein RhoQ; RIF; SIG-61; Silica-induced gene 61 protein; small GTP binding protein RhoA; small GTP binding protein RhoC; small GTPase Tc10; TC10; TC10A; Transforming protein RhoA