GFAP Polyclonal Antibody | Invitrogen OPA1-06100 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

GFAP Polyclonal Antibody

catalog :

OPA1-06100

quantity :

100 uL

price :

US 470.00

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat, zebrafish

application :

western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section

citations: 9

Reference
Jahnke L, Zandi S, Elhelbawi A, Conedera F, Enzmann V. Characterization of Macroglia Response during Tissue Repair in a Laser-Induced Model of Retinal Degeneration. Int J Mol Sci. 2023;24: pubmed publisher
Pinelis V, Krasilnikova I, Bakaeva Z, Surin A, Boyarkin D, Fisenko A, et al. Insulin Diminishes Superoxide Increase in Cytosol and Mitochondria of Cultured Cortical Neurons Treated with Toxic Glutamate. Int J Mol Sci. 2022;23: pubmed publisher
Conedera F, Pousa A, Mercader N, Tschopp M, Enzmann V. The TGFβ/Notch axis facilitates Müller cell-to-epithelial transition to ultimately form a chronic glial scar. Mol Neurodegener. 2021;16:69 pubmed publisher
Hollier P, Chapouly C, Diop A, Guimbal S, Cornuault L, Gadeau A, et al. Full-length Dhh and N-terminal Shh act as competitive antagonists to regulate angiogenesis and vascular permeability. Cardiovasc Res. 2021;117:2489-2501 pubmed publisher
Chapouly C, Hollier P, Guimbal S, Cornuault L, Gadeau A, Renault M. Desert Hedgehog-Driven Endothelium Integrity Is Enhanced by Gas1 (Growth Arrest-Specific 1) but Negatively Regulated by Cdon (Cell Adhesion Molecule-Related/Downregulated by Oncogenes). Arterioscler Thromb Vasc Biol. 2020;40:e336-e349 pubmed publisher
Chatterjee D, Mahabir S, Chatterjee D, Gerlai R. Lasting alterations induced in glial cell phenotypes by short exposure to alcohol during embryonic development in zebrafish. Addict Biol. 2021;26:e12867 pubmed publisher
Rigon L, Salvalaio M, Pederzoli F, Legnini E, Duskey J, D Avanzo F, et al. Targeting Brain Disease in MPSII: Preclinical Evaluation of IDS-Loaded PLGA Nanoparticles. Int J Mol Sci. 2019;20: pubmed publisher
Conedera F, Pousa A, Mercader N, Tschopp M, Enzmann V. Retinal microglia signaling affects Müller cell behavior in the zebrafish following laser injury induction. Glia. 2019;67:1150-1166 pubmed publisher
Aum D, Vellimana A, Singh I, Milner E, Nelson J, Han B, et al. A novel fluorescent imaging technique for assessment of cerebral vasospasm after experimental subarachnoid hemorrhage. Sci Rep. 2017;7:9126 pubmed publisher

product information

Product Type :

Antibody

Product Name :

GFAP Polyclonal Antibody

Catalog # :

OPA1-06100

Quantity :

100 uL

Price :

US 470.00

Clonality :

Polyclonal

Host :

Rabbit

Reactivity :

Human, Mouse, Rat, Zebrafish

Applications :

Immunocytochemistry: Assay-dependent, Immunohistochemistry (Frozen): 1:100-1:200, Immunohistochemistry (Paraffin): 1:100-1:200, Immunohistochemistry: Assay-dependent, Western Blot: 1:100-1:1,000

Species :

Human, Mouse, Rat, Zebrafish

Isotype :

IgG

Storage :

Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.

Description :

GFAP (Glial fibrillary acidic protein) is a member of the class III intermediate filament protein family. GFAP is heavily and specifically expressed in astrocytes and certain astroglia of the central nervous system, in satellite cells of peripheral ganglia, and in non-myelinating Schwann cells of peripheral nerves. In addition, neural stem cells strongly express GFAP. Antibodies to GFAP are very useful as markers of astrocytic cells. In addition, many types of brain tumor, presumably derived from astrocytic cells, heavily express GFAP. GFAP is also found in the lens epithelium, Kupffer cells of the liver, in some cells in salivary tumors and has been reported in erythrocytes. GFAP is used as a marker to distinguish astrocytes from other glial cells during development. Mutations in this gene cause Alexander disease, a rare disorder of astrocytes in the central nervous system. Alternative splicing of the GFAP gene results in multiple transcript variants encoding distinct isoforms.

Immunogen :

Human spinal cord.

Format :

Liquid

Applications w/Dilutions :

Immunocytochemistry: Assay-dependent, Immunohistochemistry (Frozen): 1:100-1:200, Immunohistochemistry (Paraffin): 1:100-1:200, Immunohistochemistry: Assay-dependent, Western Blot: 1:100-1:1,000

Aliases :

6330404F12Rik; 65 kDa glutamic acid decarboxylase; AI836096; ALXDRD; Astrocyte or Intermediate Filament Protein; cb345; class III intermediate filament protein; etID36982.3; FLJ45472; GAD(65); Gad2; Gad-2; GAD65; GAD-65; GFAP; GFAP epsilon; gfap protein; gfapl; glial fibrillary acidic protein; Glial Fibrillary Acidic Protein (GFAP); glial fibrillary acidic protein alpha; glutamate decarboxylase 2; Glutamate decarboxylase 65 kDa isoform; glutamic acid decarboxylase 2; I79_011607; intermediate filament; intermediate filament protein; intermediate filament protein; GFAP; Unknown (protein for MGC:139638); wu:fb34h11; wu:fk42c12; xx:af506734; zgc:110485; zGFAP; intermediate filament protein; zrf-1 antigen