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company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
Phospho-GluR1 (Ser845) Polyclonal Antibody
catalog :
OPA1-04118
quantity :
150µL
price :
US 390
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
antigen modification :
phosphorylated
reactivity :
mouse, rat
application :
western blot, immunohistochemistry, immunohistochemistry - frozen section
more info or order :
citations: 1
Published Application/Species/Sample/DilutionReference
  • western blot; mouse; 1:500; fig 3
Blanco E, Galeano P, Palomino A, Pavón F, Rivera P, Serrano A, et al. Cocaine-induced behavioral sensitization decreases the expression of endocannabinoid signaling-related proteins in the mouse hippocampus. Eur Neuropsychopharmacol. 2016;26:477-92 pubmed publisher
image
image 1 :
Invitrogen OPA1-04118 image 1
Figure 1 shows a Western blot of phospho-GluR1 (pSer845) in rat brain lysate using OPA1-04118.
product information
Product Type :
Antibody
Product Name :
Phospho-GluR1 (Ser845) Polyclonal Antibody
Catalog # :
OPA1-04118
Quantity :
150µL
Price :
US 390
Clonality :
Polyclonal
Purity :
Affinity chromatography
Host :
Rabbit
Reactivity :
Rat
Applications :
Immunohistochemistry (Frozen): 1:1000, Western Blot: 1:1,000
Species :
Rat
Isotype :
IgG
Storage :
-20°C or -80°C if preferred
Description :
GluR1 (glutamate receptor 1) is an ionotropic glutamate receptor. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter, L-glutamate, induces a conformation change that leads to the opening of the cation channel and converts the chemical signal to an electrical impulse. Then, the receptor desensitizes rapidly and enters a transiet inactive state characterized by the presence of a bound agonist. In the presence of CACNG4, CACNG7, or CACNG8 GluR1 shows resensitization which is characterized by a delayed accumulation of current flux upon continued application of glutamate.
Immunogen :
Synthetic phospho-peptide corresponding to amino acid residues surrounding Ser845 of rat GRIA1 conjugated to KLH
Format :
Liquid
Applications w/Dilutions :
Immunohistochemistry (Frozen): 1:1000, Western Blot: 1:1,000
Aliases :
2900051M01Rik; AI853806; AMPA 1; AMPA glutamate receptor; AMPA-selective glutamate receptor 1; Glr1; Glr-1; GluA1; GLUH 1; GLUH1; GluR K1; GLUR1; GluR-1; GLURA; GluR-A; GluRK1; GluR-K1; glutamate ionotropic receptor AMPA type subunit 1; glutamate receptor; Glutamate receptor 1; glutamate receptor A; Glutamate receptor ionotropic, AMPA 1; glutamate receptor subunit GluR1; glutamate receptor, ionotropic, AMPA 1; glutamate receptor, ionotropic, AMPA1 (alpha 1); GPRC1A; Gria 1; Gria1; GRM1A; HBGR1; HGBR1; HIPA; HIPA1; MGC13325; MGC133252; mGlu1; MGLUR1; MGLUR1A; NMDA1; NMDAR1; NR1; OTTHUMP00000160643; OTTHUMP00000165781; OTTHUMP00000224241; OTTHUMP00000224242; OTTHUMP00000224243; RP11-350O14.1
more info or order :
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA