This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
Smoothelin Monoclonal Antibody (R4A)
catalog :
OMA1-06020
quantity :
100 uL
price :
US 524.00
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
R4A

The same clone is also sold as:
reactivity :
human, mouse, dogs, chicken, pigs , cat
application :
western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
citations: 2
Reference
Raman P, Madhavpeddi L, Gonzales R. Palmitate induces glycosylation of cyclooxygenase-2 in primary human vascular smooth muscle cells. Am J Physiol Cell Physiol. 2018;314:C545-C553 pubmed publisher
Wamhoff B, Bowles D, Dietz N, Hu Q, Sturek M. Exercise training attenuates coronary smooth muscle phenotypic modulation and nuclear Ca2+ signaling. Am J Physiol Heart Circ Physiol. 2002;283:H2397-410 pubmed
product information
Product Type :
Antibody
Product Name :
Smoothelin Monoclonal Antibody (R4A)
Catalog # :
OMA1-06020
Quantity :
100 uL
Price :
US 524.00
Clonality :
Monoclonal
Purity :
purified
Host :
Mouse
Reactivity :
Canine, Chicken, Feline, Human, Mouse, Non-human primate, Porcine
Applications :
Immunocytochemistry: 1:100-1:200, Immunohistochemistry (Frozen): 1:100-1:200, Immunohistochemistry (Paraffin): 1:100-1:200, Western Blot: 1:100-1:1,000
Species :
Canine, Chicken, Feline, Human, Mouse, Non-human primate, Porcine
Clone :
R4A
Isotype :
IgG1
Storage :
Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.
Description :
Smoothelin is a constituent of the smooth muscle cell (SMC) cytoskeleton. Antibodies directed to smoothelin are a useful tool to monitor SMC differentiation. Smoothelin is exclusively expressed in fully differentiated (contractile) SMCs. RNA and protein analyses reveal a broad species distribution of this protein. Cells with SMC-like characteristics, such as myofibroblasts, myoepithelial cells, and skeletal and cardiac muscle do not contain smoothelin. Confocal scanning laser microscopy of tissue sections, as well as transfection studies, show a filamentous organization of smoothelin that is different from that of desmin and vimentin. Smoothelin colocalizes with actin stress fibers. Two tissue specific isoforms have been identified: a 59 kDa isoform specific for visceral SMC; and a 100 kDa specific for vascular SMC. Human smoothelin is encoded by a single copy gene which is located on chromosome 22.
Immunogen :
Cytoskeletal smoothelin extract of chicken gizzard.
Format :
Liquid
Applications w/Dilutions :
Immunocytochemistry: 1:100-1:200, Immunohistochemistry (Frozen): 1:100-1:200, Immunohistochemistry (Paraffin): 1:100-1:200, Western Blot: 1:100-1:1,000
Aliases :
FLJ35365; FLJ38597; smoothelin; smoothelin-B; smsmo; SMTN
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA