IFN gamma Monoclonal Antibody (P2C11), Biotin | Invitrogen MP701B product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

IFN gamma Monoclonal Antibody (P2C11), Biotin

catalog :

MP701B

quantity :

100µg

price :

US 305

clonality :

monoclonal

host :

mouse

conjugate :

biotin

clone name :

P2C11

reactivity :

human, pigs

application :

western blot, ELISA, blocking or activating experiments

more info or order :

Invitrogen product webpage

citations: 4

Published Application/Species/Sample/Dilution	Reference
ELISA; pigs ; 2 ug/ml	Dotti S, Guadagnini G, Salvini F, Razzuoli E, Ferrari M, Alborali G, et al. Time-course of antibody and cell-mediated immune responses to Porcine Reproductive and Respiratory Syndrome virus under field conditions. Res Vet Sci. 2013;94:510-7 pubmed publisher
ELISA; pigs ; 2 ug/ml	Razzuoli E, Villa R, Sossi E, Amadori M. Characterization of the interferon-? response of pigs to the weaning stress. J Interferon Cytokine Res. 2011;31:237-47 pubmed publisher
blocking or activating experiments; human	Moraes M, de Los Santos T, Koster M, Turecek T, Wang H, Andreyev V, et al. Enhanced antiviral activity against foot-and-mouth disease virus by a combination of type I and II porcine interferons. J Virol. 2007;81:7124-35 pubmed
	Rodríguez Gómez I, Talker S, Käser T, Stadler M, Reiter L, Ladinig A, et al. Expression of T-Bet, Eomesodermin, and GATA-3 Correlates With Distinct Phenotypes and Functional Properties in Porcine γδ T Cells. Front Immunol. 2019;10:396 pubmed publisher

product information

Product Type :

Antibody

Product Name :

IFN gamma Monoclonal Antibody (P2C11), Biotin

Catalog # :

MP701B

Quantity :

100µg

Price :

US 305

Clonality :

Monoclonal

Purity :

Protein G

Host :

Mouse

Reactivity :

Porcine

Applications :

ELISA: Assay Dependent, Western Blot: Assay Dependent

Species :

Porcine

Clone :

P2C11

Isotype :

IgG2a, kappa

Storage :

-20°C

Description :

IFN gamma (Interferon gamma, Type II interferon) is a macrophage activation factor, and immune interferon that is produced primarily by T-lymphocytes and natural killer cells in response to antigens, mitogens, Staphylococcus enterotoxin B, phytohemaglutanin and other cytokines. IFN gamma is a dimeric protein consisting of two 146 amino acid subunits. IFN gamma is a glycoprotein that exists, functionally, as a homodimer of approximately 45 kDa. On SDS-PAGE, IFN gamma appears as a combination of 25, 20 and minor 15.5 kDa bands as a result of differential glycosylation. The biological activity of the IFN gamma homodimer is highly species specific. Human IFN gamma does not show cross-reactivity with mouse. IFN gamma function includes the following: antiviral activity, tumor antiproliferative activity, induction of class I and II MHC, macrophage activation, and enhanced immunoglobulin secretion by B lymphocytes. IFN gamma is involved in cytokine regulation and also acts synergistically with other cytokines. Activation of IFN gamma takes place through binding of IFN gamma receptor I and II, and activating the JAK-STAT pathway. IFN gamma does not show any homology with IFN alpha or IFN beta but human IFN gamma shows about 40% sequence homology with mouse IFN gamma. IFN gamma is upregulated by IL2, FGF basic, EGF and downregulated by vitamin D3 or DMN. IFN gamma gene mutations are associated with aplastic anemia.

Immunogen :

Recombinant porcine IFN gamma

Format :

Liquid

Applications w/Dilutions :

ELISA: Assay Dependent, Western Blot: Assay Dependent

Aliases :

BoIFNG; BOS_5228; cytokine; EGK_03901; gamma interferon; gamma-interferon; gamma-interferon precursor (AA -23 to 143); H-IFN-g; IFG; IFI; IFN gamma; IFN ?; IFNG; IFN-g; IFNG2; IFN-gamma; IFN-gamma precursor; IFN-y; IFN?; Immune interferon; Interferon gamma; interferon gamma precursor; interferon gamma type 2; Interferon y; Interferon ?; interferon, gamma; interferon-gama; interferon-gamma; Interferon-gamma level; Interferon?; M-IFN-g; R-IFN-g

more info or order :

Invitrogen product webpage