Phospho-Tau (Thr212, Ser214) Monoclonal Antibody (AT100) | Invitrogen MN1060 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

Phospho-Tau (Thr212, Ser214) Monoclonal Antibody (AT100)

catalog :

MN1060

quantity :

100 µg

price :

US 588

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

antigen modification :

phosphorylated

clone name :

AT100

reactivity :

hamsters, leopard cat, human, mouse, rat, cat, fruit fly

application :

western blot, ELISA, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section, immunohistochemistry - free floating section

more info or order :

Invitrogen product webpage

citations: 648

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry; mouse; 1:1000; loading ...; fig 4d	Zhang X, Zou L, Meng L, Xiong M, Pan L, Chen G, et al. Amphiphysin I cleavage by asparagine endopeptidase leads to tau hyperphosphorylation and synaptic dysfunction. elife. 2021;10: pubmed publisher
immunohistochemistry; human; 1:500; loading ...; fig 5d	Haytural H, Jordà Siquier T, Winblad B, Mulle C, Tjernberg L, Granholm A, et al. Distinctive alteration of presynaptic proteins in the outer molecular layer of the dentate gyrus in Alzheimer's disease. Brain Commun. 2021;3:fcab079 pubmed publisher
immunohistochemistry; mouse; 1:200; loading ...; fig 1g	Galán Ganga M, Rodríguez Cueto C, Merchán Rubira J, Hernandez F, Avila J, Posada Ayala M, et al. Cannabinoid receptor CB2 ablation protects against TAU induced neurodegeneration. Acta Neuropathol Commun. 2021;9:90 pubmed publisher
immunohistochemistry - free floating section; mouse; loading ...; fig 5i	Gary C, Lam S, Herard A, Koch J, Petit F, Gipchtein P, et al. Encephalopathy induced by Alzheimer brain inoculation in a non-human primate. Acta Neuropathol Commun. 2019;7:126 pubmed publisher
western blot; mouse; 1:1000; loading ...; fig 2c	Chang H, Di T, Wang Y, Zeng X, Li G, Wan Q, et al. Seipin deletion in mice enhances phosphorylation and aggregation of tau protein through reduced neuronal PPARγ and insulin resistance. Neurobiol Dis. 2019;127:350-361 pubmed publisher
immunohistochemistry; human; 1:400; loading ...; fig 1c	Falcon B, Zivanov J, Zhang W, Murzin A, Garringer H, Vidal R, et al. Novel tau filament fold in chronic traumatic encephalopathy encloses hydrophobic molecules. Nature. 2019;568:420-423 pubmed publisher
immunohistochemistry; mouse; loading ...; fig 4 western blot; mouse; 1:1000; loading ...; fig 4b	Zhang Z, Obianyo O, Dall E, Du Y, Fu H, Liu X, et al. Inhibition of delta-secretase improves cognitive functions in mouse models of Alzheimer's disease. Nat Commun. 2017;8:14740 pubmed publisher
immunohistochemistry - free floating section; mouse; loading ...; fig s4b	Fu H, Rodriguez G, Herman M, Emrani S, Nahmani E, Barrett G, et al. Tau Pathology Induces Excitatory Neuron Loss, Grid Cell Dysfunction, and Spatial Memory Deficits Reminiscent of Early Alzheimer's Disease. Neuron. 2017;93:533-541.e5 pubmed publisher
immunohistochemistry; mouse; 1:100; loading ...; fig 4e	Koukouli F, Rooy M, Maskos U. Early and progressive deficit of neuronal activity patterns in a model of local amyloid pathology in mouse prefrontal cortex. Aging (Albany NY). 2016;8:3430-3449 pubmed publisher
western blot; mouse; loading ...; fig 6e	Laurent C, Dorothee G, Hunot S, Martin E, Monnet Y, Duchamp M, et al. Hippocampal T cell infiltration promotes neuroinflammation and cognitive decline in a mouse model of tauopathy. Brain. 2017;140:184-200 pubmed publisher
immunohistochemistry; human; 1:200; loading ...; fig 1e	Ling H, Kovacs G, Vonsattel J, DAVEY K, Mok K, Hardy J, et al. Astrogliopathy predominates the earliest stage of corticobasal degeneration pathology. Brain. 2016;139:3237-3252 pubmed
immunohistochemistry - paraffin section; rat; 1:500; fig 6	Steffen J, Krohn M, Paarmann K, Schwitlick C, BrÃ¼ning T, Marreiros R, et al. Revisiting rodent models: Octodon degus as Alzheimer's disease model?. Acta Neuropathol Commun. 2016;4:91 pubmed publisher
western blot; mouse; 1:500; loading ...; fig ev1	Salta E, Sierksma A, Vanden Eynden E, De Strooper B. miR-132 loss de-represses ITPKB and aggravates amyloid and TAU pathology in Alzheimer's brain. EMBO Mol Med. 2016;8:1005-18 pubmed publisher
immunohistochemistry - free floating section; mouse; 1:250; loading ...; fig st7 immunohistochemistry - paraffin section; mouse; 1:250; loading ...; fig st7	Pajares M, Jiménez Moreno N, García Yagüe A, Escoll M, De Ceballos M, Van Leuven F, et al. Transcription factor NFE2L2/NRF2 is a regulator of macroautophagy genes. Autophagy. 2016;12:1902-1916 pubmed
western blot; mouse; 1:500; fig 6	Herring A, Münster Y, Akkaya T, Moghaddam S, Deinsberger K, Meyer J, et al. Kallikrein-8 inhibition attenuates Alzheimer's disease pathology in mice. Alzheimers Dement. 2016;12:1273-1287 pubmed publisher
western blot; mouse; 1:1000; fig 3	Polanco J, Scicluna B, Hill A, Götz J. Extracellular Vesicles Isolated from the Brains of rTg4510 Mice Seed Tau Protein Aggregation in a Threshold-dependent Manner. J Biol Chem. 2016;291:12445-66 pubmed publisher
immunohistochemistry - paraffin section; human; fig 1	Pisa D, Alonso R, RÃ¡bano A, Carrasco L. Corpora Amylacea of Brain Tissue from Neurodegenerative Diseases Are Stained with Specific Antifungal Antibodies. Front Neurosci. 2016;10:86 pubmed publisher
western blot; human; 1:2000; fig 4	Gorsky M, Burnouf S, Dols J, Mandelkow E, Partridge L. Acetylation mimic of lysine 280 exacerbates human Tau neurotoxicity in vivo. Sci Rep. 2016;6:22685 pubmed publisher
immunohistochemistry - paraffin section; mouse; 1:500; fig 1	Van der Jeugd A, Vermaercke B, Halliday G, Staufenbiel M, GÃ¶tz J. Impulsivity, decreased social exploration, and executive dysfunction in a mouse model of frontotemporal dementia. Neurobiol Learn Mem. 2016;130:34-43 pubmed publisher
western blot; human; 1:1000; fig 3 western blot; mouse; 1:1000; fig 3	Jiang T, Zhang Y, Chen Q, Gao Q, Zhu X, Zhou J, et al. TREM2 modifies microglial phenotype and provides neuroprotection in P301S tau transgenic mice. Neuropharmacology. 2016;105:196-206 pubmed publisher
western blot; human; fig s2	GarcÃa AyllÃ³n M, Botella LÃ³pez A, Cuchillo IbaÃ±ez I, RÃ¡bano A, Andreasen N, Blennow K, et al. HNK-1 Carrier Glycoproteins Are Decreased in the Alzheimer's Disease Brain. Mol Neurobiol. 2017;54:188-199 pubmed publisher
immunohistochemistry - paraffin section; cat; 1:100; fig 6	Chambers J, Tokuda T, Uchida K, Ishii R, Tatebe H, Takahashi E, et al. The domestic cat as a natural animal model of Alzheimer's disease. Acta Neuropathol Commun. 2015;3:78 pubmed publisher
western blot; mouse; 1:200; fig 1	Elahi M, Motoi Y, Matsumoto S, Hasan Z, Ishiguro K, Hattori N. Short-term treadmill exercise increased tau insolubility and neuroinflammation in tauopathy model mice. Neurosci Lett. 2016;610:207-12 pubmed publisher
immunohistochemistry - paraffin section; human; 1:100; fig 3	Nishikawa T, Takahashi T, Nakamori M, Hosomi N, Maruyama H, Miyazaki Y, et al. The identification of raft-derived tau-associated vesicles that are incorporated into immature tangles and paired helical filaments. Neuropathol Appl Neurobiol. 2016;42:639-653 pubmed publisher
immunohistochemistry - paraffin section; human; 1:50; fig 1	Pisa D, Alonso R, RÃ¡bano A, Rodal I, Carrasco L. Different Brain Regions are Infected with Fungi in Alzheimer's Disease. Sci Rep. 2015;5:15015 pubmed publisher
immunohistochemistry; human; 1 ug/ml western blot; human; 1:1000; fig 3	Wagner J, Krauss S, Shi S, Ryazanov S, Steffen J, Miklitz C, et al. Reducing tau aggregates with anle138b delays disease progression in a mouse model of tauopathies. Acta Neuropathol. 2015;130:619-31 pubmed publisher
immunohistochemistry - paraffin section; mouse; fig 1	Violet M, Chauderlier A, Delattre L, Tardivel M, Chouala M, Sultan A, et al. Prefibrillar Tau oligomers alter the nucleic acid protective function of Tau in hippocampal neurons in vivo. Neurobiol Dis. 2015;82:540-551 pubmed publisher
western blot; human; fig s2	Richter M, Mewes A, Fritsch M, KrÃ¼gel U, Hoffmann R, Singer D. Doubly Phosphorylated Peptide Vaccines to Protect Transgenic P301S Mice against Alzheimer's Disease Like Tau Aggregation. Vaccines (Basel). 2014;2:601-23 pubmed publisher
immunohistochemistry; hamsters; 1:10,000; fig 2	Bullmann T, Seeger G, Stieler J, Hanics J, Reimann K, Kretzschmann T, et al. Tau phosphorylation-associated spine regression does not impair hippocampal-dependent memory in hibernating golden hamsters. Hippocampus. 2016;26:301-18 pubmed publisher
immunocytochemistry; mouse; 1:1000; fig 1	Brelstaff J, Ossola B, Neher J, Klingstedt T, Nilsson K, Goedert M, et al. The fluorescent pentameric oligothiophene pFTAA identifies filamentous tau in live neurons cultured from adult P301S tau mice. Front Neurosci. 2015;9:184 pubmed publisher
ELISA; human; fig s1e	Song L, Lu S, Ouyang X, Melchor J, Lee J, Terracina G, et al. Analysis of tau post-translational modifications in rTg4510 mice, a model of tau pathology. Mol Neurodegener. 2015;10:14 pubmed publisher
immunohistochemistry; mouse; 1:100	Miller N, Feng Z, Edens B, Yang B, Shi H, Sze C, et al. Non-aggregating tau phosphorylation by cyclin-dependent kinase 5 contributes to motor neuron degeneration in spinal muscular atrophy. J Neurosci. 2015;35:6038-50 pubmed publisher
immunohistochemistry - paraffin section; mouse; 1:300; fig 6	Hansen H, Fabricius K, Barkholt P, Niehoff M, Morley J, Jelsing J, et al. The GLP-1 Receptor Agonist Liraglutide Improves Memory Function and Increases Hippocampal CA1 Neuronal Numbers in a Senescence-Accelerated Mouse Model of Alzheimer's Disease. J Alzheimers Dis. 2015;46:877-88 pubmed publisher
western blot; human; fig 3, 4	Sepúlveda Díaz J, Alavi Naini S, Huynh M, Ouidja M, Yanicostas C, Chantepie S, et al. HS3ST2 expression is critical for the abnormal phosphorylation of tau in Alzheimer's disease-related tau pathology. Brain. 2015;138:1339-54 pubmed publisher
immunohistochemistry - paraffin section; human; 1:200	Takeuchi R, Toyoshima Y, Tada M, Tanaka H, Shimizu H, Shiga A, et al. Globular Glial Mixed Four Repeat Tau and TDP-43 Proteinopathy with Motor Neuron Disease and Frontotemporal Dementia. Brain Pathol. 2016;26:82-94 pubmed publisher
western blot; rat; 1:1000; fig 1	Li R, Xu D, Ma T. Lovastatin suppresses the aberrant tau phosphorylation from FTDP-17 mutation and okadaic acid-induction in rat primary neurons. Neuroscience. 2015;294:14-20 pubmed publisher
western blot; mouse	Mouton Liger F, Rebillat A, Gourmaud S, Paquet C, Leguen A, Dumurgier J, et al. PKR downregulation prevents neurodegeneration and Î²-amyloid production in a thiamine-deficient model. Cell Death Dis. 2015;6:e1594 pubmed publisher
immunohistochemistry - frozen section; mouse; 1:100 western blot; mouse; 1:1000	HÃ¶llerhage M, Deck R, de Andrade A, Respondek G, Xu H, RÃ¶sler T, et al. Piericidin A aggravates Tau pathology in P301S transgenic mice. PLoS ONE. 2014;9:e113557 pubmed publisher
immunohistochemistry - paraffin section; human; 1:500; fig 2 western blot; human; 1:1000; fig 4	Ohia Nwoko O, Montazari S, Lau Y, Eriksen J. Long-term treadmill exercise attenuates tau pathology in P301S tau transgenic mice. Mol Neurodegener. 2014;9:54 pubmed publisher
immunocytochemistry; human; 1:1000; fig 5	Falcon B, Cavallini A, Angers R, Glover S, Murray T, Barnham L, et al. Conformation determines the seeding potencies of native and recombinant Tau aggregates. J Biol Chem. 2015;290:1049-65 pubmed publisher
western blot; mouse; fig 2	Castro Alvarez J, Uribe Arias S, Kosik K, Cardona GÃ³mez G. Long- and short-term CDK5 knockdown prevents spatial memory dysfunction and tau pathology of triple transgenic Alzheimer's mice. Front Aging Neurosci. 2014;6:243 pubmed publisher
immunohistochemistry - free floating section; rat; 1:70	Forny Germano L, Lyra e Silva N, Batista A, Brito Moreira J, Gralle M, Boehnke S, et al. Alzheimer's disease-like pathology induced by amyloid-Î² oligomers in nonhuman primates. J Neurosci. 2014;34:13629-43 pubmed publisher
western blot; human; fig 4	Dunn H, Ager R, Baglietto Vargas D, Cheng D, Kitazawa M, Cribbs D, et al. Restoration of lipoxin A4 signaling reduces Alzheimer's disease-like pathology in the 3xTg-AD mouse model. J Alzheimers Dis. 2015;43:893-903 pubmed publisher
immunocytochemistry; human; 1:250	Kohler C, Dinekov M, Götz J. Granulovacuolar degeneration and unfolded protein response in mouse models of tauopathy and A? amyloidosis. Neurobiol Dis. 2014;71:169-79 pubmed publisher
immunohistochemistry - paraffin section; mouse; fig 1 western blot; mouse; fig 1	Ittner A, Bertz J, Suh L, Stevens C, Götz J, Ittner L. Tau-targeting passive immunization modulates aspects of pathology in tau transgenic mice. J Neurochem. 2015;132:135-45 pubmed publisher
western blot; mouse	Rao M, McBrayer M, Campbell J, Kumar A, Hashim A, Sershen H, et al. Specific calpain inhibition by calpastatin prevents tauopathy and neurodegeneration and restores normal lifespan in tau P301L mice. J Neurosci. 2014;34:9222-34 pubmed publisher
western blot; human; 1:1000	Jiang T, Yu J, Zhu X, Zhang Q, Cao L, Wang H, et al. Temsirolimus attenuates tauopathy in vitro and in vivo by targeting tau hyperphosphorylation and autophagic clearance. Neuropharmacology. 2014;85:121-30 pubmed publisher
immunohistochemistry; mouse; 1:50	Inoue H, Hiradate Y, Shirakata Y, Kanai K, Kosaka K, Gotoh A, et al. Site-specific phosphorylation of Tau protein is associated with deacetylation of microtubules in mouse spermatogenic cells during meiosis. FEBS Lett. 2014;588:2003-8 pubmed publisher
immunohistochemistry; mouse; 1:1000 western blot; mouse; 1:1000	Castillo Carranza D, Sengupta U, Guerrero Muñoz M, Lasagna Reeves C, Gerson J, Singh G, et al. Passive immunization with Tau oligomer monoclonal antibody reverses tauopathy phenotypes without affecting hyperphosphorylated neurofibrillary tangles. J Neurosci. 2014;34:4260-72 pubmed publisher
immunohistochemistry - free floating section; human; fig 1	Stancu I, Ris L, Vasconcelos B, Marinangeli C, Goeminne L, Laporte V, et al. Tauopathy contributes to synaptic and cognitive deficits in a murine model for Alzheimer's disease. FASEB J. 2014;28:2620-31 pubmed publisher
immunohistochemistry; rat; 1:400	Dujardin S, Lécolle K, Caillierez R, Bégard S, Zommer N, Lachaud C, et al. Neuron-to-neuron wild-type Tau protein transfer through a trans-synaptic mechanism: relevance to sporadic tauopathies. Acta Neuropathol Commun. 2014;2:14 pubmed publisher
western blot; mouse; 1:1000	Abbondante S, Baglietto Vargas D, Rodriguez Ortiz C, Estrada Hernandez T, Medeiros R, LaFerla F. Genetic ablation of tau mitigates cognitive impairment induced by type 1 diabetes. Am J Pathol. 2014;184:819-26 pubmed publisher
immunohistochemistry; mouse; 1:100	Yamada E, Respondek G, Müssner S, de Andrade A, Höllerhage M, Depienne C, et al. Annonacin, a natural lipophilic mitochondrial complex I inhibitor, increases phosphorylation of tau in the brain of FTDP-17 transgenic mice. Exp Neurol. 2014;253:113-25 pubmed publisher
immunohistochemistry; mouse; 1:200	Hoffmann N, Dorostkar M, Blumenstock S, Goedert M, Herms J. Impaired plasticity of cortical dendritic spines in P301S tau transgenic mice. Acta Neuropathol Commun. 2013;1:82 pubmed publisher
immunohistochemistry; human; 1:1000	Notter T, Knuesel I. Reelin immunoreactivity in neuritic varicosities in the human hippocampal formation of non-demented subjects and Alzheimer's disease patients. Acta Neuropathol Commun. 2013;1:27 pubmed publisher
western blot; human; 1:1000	Baglietto Vargas D, Kitazawa M, Le E, Estrada Hernandez T, Rodriguez Ortiz C, Medeiros R, et al. Endogenous murine tau promotes neurofibrillary tangles in 3xTg-AD mice without affecting cognition. Neurobiol Dis. 2014;62:407-15 pubmed publisher
immunohistochemistry; human western blot; human	Ozcelik S, Fraser G, Castets P, Schaeffer V, Skachokova Z, Breu K, et al. Rapamycin attenuates the progression of tau pathology in P301S tau transgenic mice. PLoS ONE. 2013;8:e62459 pubmed publisher
immunohistochemistry - paraffin section; mouse; fig 4	Clippinger A, D Alton S, Lin W, Gendron T, Howard J, Borchelt D, et al. Robust cytoplasmic accumulation of phosphorylated TDP-43 in transgenic models of tauopathy. Acta Neuropathol. 2013;126:39-50 pubmed publisher
western blot; human; 1:1000 immunohistochemistry; rat; 1:400	Caillierez R, Bégard S, Lécolle K, Deramecourt V, Zommer N, Dujardin S, et al. Lentiviral delivery of the human wild-type tau protein mediates a slow and progressive neurodegenerative tau pathology in the rat brain. Mol Ther. 2013;21:1358-68 pubmed publisher
western blot; human	Ozdemir A, Rom I, Kovalevich J, Yen W, Adiga R, Dave R, et al. PINCH in the cellular stress response to tau-hyperphosphorylation. PLoS ONE. 2013;8:e58232 pubmed publisher
western blot; mouse; 1:1000	Alonso E, Vale C, Vieytes M, Botana L. Translocation of PKC by yessotoxin in an in vitro model of Alzheimer's disease with improvement of tau and ?-amyloid pathology. ACS Chem Neurosci. 2013;4:1062-70 pubmed publisher
immunocytochemistry; fruit fly ; fig s4	Wu T, Lu Y, Chuang C, Wu C, Chiang A, Krantz D, et al. Loss of vesicular dopamine release precedes tauopathy in degenerative dopaminergic neurons in a Drosophila model expressing human tau. Acta Neuropathol. 2013;125:711-25 pubmed publisher
immunohistochemistry; human; 1:100	Klingstedt T, Blechschmidt C, Nogalska A, Prokop S, Häggqvist B, Danielsson O, et al. Luminescent conjugated oligothiophenes for sensitive fluorescent assignment of protein inclusion bodies. Chembiochem. 2013;14:607-16 pubmed publisher
immunohistochemistry; mouse	Garringer H, Murrell J, Sammeta N, Gnezda A, Ghetti B, Vidal R. Increased tau phosphorylation and tau truncation, and decreased synaptophysin levels in mutant BRI2/tau transgenic mice. PLoS ONE. 2013;8:e56426 pubmed publisher
western blot; mouse; 1:2000	Desrumaux C, Pisoni A, Meunier J, Deckert V, Athias A, Perrier V, et al. Increased amyloid-? peptide-induced memory deficits in phospholipid transfer protein (PLTP) gene knockout mice. Neuropsychopharmacology. 2013;38:817-25 pubmed publisher
western blot; rat; 1:3000	Zussy C, Brureau A, Keller E, Marchal S, Blayo C, Delair B, et al. Alzheimer's disease related markers, cellular toxicity and behavioral deficits induced six weeks after oligomeric amyloid-? peptide injection in rats. PLoS ONE. 2013;8:e53117 pubmed publisher
immunohistochemistry; human; 1:200	Schön C, Hoffmann N, Ochs S, Burgold S, Filser S, Steinbach S, et al. Long-term in vivo imaging of fibrillar tau in the retina of P301S transgenic mice. PLoS ONE. 2012;7:e53547 pubmed publisher
immunohistochemistry; human; 1:100 western blot; human; 1:1000 immunohistochemistry; mouse; 1:250; loading ...; fig 5a	Kohler C, Dinekov M, Götz J. Active glycogen synthase kinase-3 and tau pathology-related tyrosine phosphorylation in pR5 human tau transgenic mice. Neurobiol Aging. 2013;34:1369-79 pubmed publisher
western blot; mouse	Leboucher A, Laurent C, Fernandez Gomez F, Burnouf S, Troquier L, Eddarkaoui S, et al. Detrimental effects of diet-induced obesity on ? pathology are independent of insulin resistance in ? transgenic mice. Diabetes. 2013;62:1681-8 pubmed publisher
western blot; rat; 1:1000	Rahman A, Khan K, Al Khaledi G, Khan I, Attur S. Early postnatal lead exposure induces tau phosphorylation in the brain of young rats. Acta Biol Hung. 2012;63:411-25 pubmed publisher
immunohistochemistry; mouse; 1:1000	Burnouf S, Martire A, Derisbourg M, Laurent C, Belarbi K, Leboucher A, et al. NMDA receptor dysfunction contributes to impaired brain-derived neurotrophic factor-induced facilitation of hippocampal synaptic transmission in a Tau transgenic model. Aging Cell. 2013;12:11-23 pubmed publisher
immunohistochemistry - paraffin section; leopard cat; 1:100; fig 6	Chambers J, Uchida K, Harada T, Tsuboi M, Sato M, Kubo M, et al. Neurofibrillary tangles and the deposition of a beta amyloid peptide with a novel N-terminal epitope in the brains of wild Tsushima leopard cats. PLoS ONE. 2012;7:e46452 pubmed publisher
immunohistochemistry; mouse	Inoue K, Rispoli J, Kaphzan H, Klann E, Chen E, Kim J, et al. Macroautophagy deficiency mediates age-dependent neurodegeneration through a phospho-tau pathway. Mol Neurodegener. 2012;7:48 pubmed publisher
immunohistochemistry; human; 1:100	Collins M, Riascos D, Kovalik T, An J, Krupa K, Krupa K, et al. The RNA-binding motif 45 (RBM45) protein accumulates in inclusion bodies in amyotrophic lateral sclerosis (ALS) and frontotemporal lobar degeneration with TDP-43 inclusions (FTLD-TDP) patients. Acta Neuropathol. 2012;124:717-32 pubmed publisher
immunocytochemistry; human; 1:100	Mondragón Rodríguez S, Trillaud Doppia E, Dudilot A, Bourgeois C, Lauzon M, Leclerc N, et al. Interaction of endogenous tau protein with synaptic proteins is regulated by N-methyl-D-aspartate receptor-dependent tau phosphorylation. J Biol Chem. 2012;287:32040-53 pubmed publisher
western blot; human; 1:1000	Bretteville A, Marcouiller F, Julien C, El Khoury N, Petry F, Poitras I, et al. Hypothermia-induced hyperphosphorylation: a new model to study tau kinase inhibitors. Sci Rep. 2012;2:480 pubmed publisher
western blot; mouse; 1:1000	Krstic D, Madhusudan A, Doehner J, Vogel P, Notter T, Imhof C, et al. Systemic immune challenges trigger and drive Alzheimer-like neuropathology in mice. J Neuroinflammation. 2012;9:151 pubmed publisher
immunohistochemistry; human; 1:400	Deramecourt V, Lebert F, Maurage C, Fernandez Gomez F, Dujardin S, Colin M, et al. Clinical, neuropathological, and biochemical characterization of the novel tau mutation P332S. J Alzheimers Dis. 2012;31:741-9 pubmed publisher
western blot; mouse; 1:500	Cancino G, Miller F, Kaplan D. p73 haploinsufficiency causes tau hyperphosphorylation and tau kinase dysregulation in mouse models of aging and Alzheimer's disease. Neurobiol Aging. 2013;34:387-99 pubmed publisher
western blot; mouse	Fine J, Baillargeon A, Renner D, Hoerster N, Tokarev J, Colton S, et al. Intranasal deferoxamine improves performance in radial arm water maze, stabilizes HIF-1?, and phosphorylates GSK3? in P301L tau transgenic mice. Exp Brain Res. 2012;219:381-90 pubmed publisher
immunohistochemistry; mouse	Vidal R, Sammeta N, Garringer H, Sambamurti K, Miravalle L, Lamb B, et al. The Psen1-L166P-knock-in mutation leads to amyloid deposition in human wild-type amyloid precursor protein YAC transgenic mice. FASEB J. 2012;26:2899-910 pubmed publisher
western blot; rat; 1:1000	Rahman A, Khan K, Al Khaledi G, Khan I, Al Shemary T. Over activation of hippocampal serine/threonine protein phosphatases PP1 and PP2A is involved in lead-induced deficits in learning and memory in young rats. Neurotoxicology. 2012;33:370-83 pubmed publisher
western blot; human	Kawakami F, Yabata T, Ohta E, Maekawa T, Shimada N, Suzuki M, et al. LRRK2 phosphorylates tubulin-associated tau but not the free molecule: LRRK2-mediated regulation of the tau-tubulin association and neurite outgrowth. PLoS ONE. 2012;7:e30834 pubmed publisher
immunohistochemistry; mouse; 1:400	Troquier L, Caillierez R, Burnouf S, Fernandez Gomez F, Grosjean M, Zommer N, et al. Targeting phospho-Ser422 by active Tau Immunotherapy in the THYTau22 mouse model: a suitable therapeutic approach. Curr Alzheimer Res. 2012;9:397-405 pubmed
immunohistochemistry; mouse; 1:6400	Nijholt D, van Haastert E, Rozemuller A, Scheper W, Hoozemans J. The unfolded protein response is associated with early tau pathology in the hippocampus of tauopathies. J Pathol. 2012;226:693-702 pubmed publisher
immunohistochemistry; mouse	Ohmi K, Zhao H, Neufeld E. Defects in the medial entorhinal cortex and dentate gyrus in the mouse model of Sanfilippo syndrome type B. PLoS ONE. 2011;6:e27461 pubmed publisher
immunohistochemistry; human; 1:2000 western blot; human	Kitazawa M, Cheng D, Tsukamoto M, Koike M, Wes P, Vasilevko V, et al. Blocking IL-1 signaling rescues cognition, attenuates tau pathology, and restores neuronal ?-catenin pathway function in an Alzheimer's disease model. J Immunol. 2011;187:6539-49 pubmed publisher
western blot; human; 1:1000	Alonso E, Vale C, Vieytes M, LaFerla F, Gimenez Llort L, Botana L. 13-Desmethyl spirolide-C is neuroprotective and reduces intracellular A? and hyperphosphorylated tau in vitro. Neurochem Int. 2011;59:1056-65 pubmed publisher
immunohistochemistry; mouse	Emmer K, Waxman E, Covy J, Giasson B. E46K human alpha-synuclein transgenic mice develop Lewy-like and tau pathology associated with age-dependent, detrimental motor impairment. J Biol Chem. 2011;286:35104-18 pubmed publisher
western blot; human; 1:1000	Tran H, LaFerla F, Holtzman D, Brody D. Controlled cortical impact traumatic brain injury in 3xTg-AD mice causes acute intra-axonal amyloid-? accumulation and independently accelerates the development of tau abnormalities. J Neurosci. 2011;31:9513-25 pubmed publisher
immunohistochemistry; human; 1:400	Belarbi K, Burnouf S, Fernandez Gomez F, Laurent C, Lestavel S, Figeac M, et al. Beneficial effects of exercise in a transgenic mouse model of Alzheimer's disease-like Tau pathology. Neurobiol Dis. 2011;43:486-94 pubmed publisher
immunohistochemistry; human; 1:200 western blot; human; 1:200	Kovacs G, Molnár K, Laszlo L, Strobel T, Botond G, Hönigschnabl S, et al. A peculiar constellation of tau pathology defines a subset of dementia in the elderly. Acta Neuropathol. 2011;122:205-22 pubmed publisher
western blot; mouse; 1:1,000	Koike M, Garcia F, Kitazawa M, Green K, LaFerla F. Long term changes in phospho-APP and tau aggregation in the 3xTg-AD mice following cerebral ischemia. Neurosci Lett. 2011;495:55-9 pubmed publisher
immunohistochemistry; mouse; 1:200	Kudo L, Parfenova L, Ren G, Vi N, Hui M, Ma Z, et al. Puromycin-sensitive aminopeptidase (PSA/NPEPPS) impedes development of neuropathology in hPSA/TAU(P301L) double-transgenic mice. Hum Mol Genet. 2011;20:1820-33 pubmed publisher
western blot; hamsters; 1:500	Stieler J, Bullmann T, Kohl F, Tøien Ø, Brückner M, Hartig W, et al. The physiological link between metabolic rate depression and tau phosphorylation in mammalian hibernation. PLoS ONE. 2011;6:e14530 pubmed publisher
immunohistochemistry; mouse; 0.02 ug/mL	Fonseca M, Chu S, Berci A, Benoit M, Peters D, Kimura Y, et al. Contribution of complement activation pathways to neuropathology differs among mouse models of Alzheimer's disease. J Neuroinflammation. 2011;8:4 pubmed publisher
immunohistochemistry; rat western blot; rat	Filipcik P, Zilka N, Bugos O, Kučerák J, Koson P, Novak P, et al. First transgenic rat model developing progressive cortical neurofibrillary tangles. Neurobiol Aging. 2012;33:1448-56 pubmed publisher
immunohistochemistry; human western blot; human immunohistochemistry; mouse western blot; mouse	Van der Jeugd A, Ahmed T, Burnouf S, Belarbi K, Hamdame M, Grosjean M, et al. Hippocampal tauopathy in tau transgenic mice coincides with impaired hippocampus-dependent learning and memory, and attenuated late-phase long-term depression of synaptic transmission. Neurobiol Learn Mem. 2011;95:296-304 pubmed publisher
immunohistochemistry; human; 1:1000 western blot; human; 1:1000	Colodner K, Feany M. Glial fibrillary tangles and JAK/STAT-mediated glial and neuronal cell death in a Drosophila model of glial tauopathy. J Neurosci. 2010;30:16102-13 pubmed publisher
immunohistochemistry; human western blot; human	Bose A, Mouton Liger F, Paquet C, Mazot P, Vigny M, Gray F, et al. Modulation of tau phosphorylation by the kinase PKR: implications in Alzheimer's disease. Brain Pathol. 2011;21:189-200 pubmed publisher
immunohistochemistry; fruit fly western blot; fruit fly	Lin C, Tsai P, Wu R, Chien C. LRRK2 G2019S mutation induces dendrite degeneration through mislocalization and phosphorylation of tau by recruiting autoactivated GSK3ß. J Neurosci. 2010;30:13138-49 pubmed publisher
immunohistochemistry; human; 1:3,000	Seidel K, den Dunnen W, Schultz C, Paulson H, Frank S, de Vos R, et al. Axonal inclusions in spinocerebellar ataxia type 3. Acta Neuropathol. 2010;120:449-60 pubmed publisher
immunocytochemistry; rat; 1:10	Bertrand J, Sénéchal P, Zummo Soucy M, Plouffe V, Leclerc N. The formation of tau pathological phospho-epitopes in the axon is prevented by the dephosphorylation of selective sites in primary hippocampal neurons over-expressing human tau. J Neurochem. 2010;114:1353-67 pubmed publisher
western blot; human; 1:1000	Koike M, Green K, Blurton Jones M, LaFerla F. Oligemic hypoperfusion differentially affects tau and amyloid-{beta}. Am J Pathol. 2010;177:300-10 pubmed publisher
immunohistochemistry; human; 1:5000 western blot; human; 1:1000	Martinez Coria H, Green K, Billings L, Kitazawa M, Albrecht M, Rammes G, et al. Memantine improves cognition and reduces Alzheimer's-like neuropathology in transgenic mice. Am J Pathol. 2010;176:870-80 pubmed publisher
immunocytochemistry; human; 1:100 western blot; human immunocytochemistry; mouse; 1:100 western blot; mouse	Vale C, Alonso E, Rubiolo J, Vieytes M, LaFerla F, Gimenez Llort L, et al. Profile for amyloid-beta and tau expression in primary cortical cultures from 3xTg-AD mice. Cell Mol Neurobiol. 2010;30:577-90 pubmed publisher
western blot; human; 1:1000	van Eersel J, Bi M, Ke Y, Hodges J, Xuereb J, Gregory G, et al. Phosphorylation of soluble tau differs in Pick's disease and Alzheimer's disease brains. J Neural Transm (Vienna). 2009;116:1243-51 pubmed publisher
western blot; human	Rahman A, Ting K, Cullen K, Braidy N, Brew B, Guillemin G. The excitotoxin quinolinic acid induces tau phosphorylation in human neurons. PLoS ONE. 2009;4:e6344 pubmed publisher
immunocytochemistry; human; 1:1000	Nogalska A, Terracciano C, D Agostino C, King Engel W, Askanas V. p62/SQSTM1 is overexpressed and prominently accumulated in inclusions of sporadic inclusion-body myositis muscle fibers, and can help differentiating it from polymyositis and dermatomyositis. Acta Neuropathol. 2009;118:407-13 pubmed publisher
immunohistochemistry; human; 1:1000 western blot; human; 1:200	Clavaguera F, Bolmont T, Crowther R, Abramowski D, Frank S, Probst A, et al. Transmission and spreading of tauopathy in transgenic mouse brain. Nat Cell Biol. 2009;11:909-13 pubmed publisher
western blot; mouse	Ittner L, Ke Y, Götz J. Phosphorylated Tau interacts with c-Jun N-terminal kinase-interacting protein 1 (JIP1) in Alzheimer disease. J Biol Chem. 2009;284:20909-16 pubmed publisher
immunohistochemistry; mouse	Ohmi K, Kudo L, Ryazantsev S, Zhao H, Karsten S, Neufeld E. Sanfilippo syndrome type B, a lysosomal storage disease, is also a tauopathy. Proc Natl Acad Sci U S A. 2009;106:8332-7 pubmed publisher
immunohistochemistry; mouse; 1:10	Capsoni S, Covaceuszach S, Ugolini G, Spirito F, Vignone D, Stefanini B, et al. Delivery of NGF to the brain: intranasal versus ocular administration in anti-NGF transgenic mice. J Alzheimers Dis. 2009;16:371-88 pubmed publisher
western blot; fruit fly ; 1:2,000	Chatterjee S, Sang T, Lawless G, Jackson G. Dissociation of tau toxicity and phosphorylation: role of GSK-3beta, MARK and Cdk5 in a Drosophila model. Hum Mol Genet. 2009;18:164-77 pubmed publisher
immunocytochemistry; human; 1:100	Rossi G, Dalprà L, Crosti F, Lissoni S, Sciacca F, Catania M, et al. A new function of microtubule-associated protein tau: involvement in chromosome stability. Cell Cycle. 2008;7:1788-94 pubmed
immunocytochemistry; human	Fein J, Sokolow S, Miller C, Vinters H, Yang F, Cole G, et al. Co-localization of amyloid beta and tau pathology in Alzheimer's disease synaptosomes. Am J Pathol. 2008;172:1683-92 pubmed publisher
western blot; fruit fly ; 1:100,000	Steinhilb M, Dias Santagata D, Fulga T, Felch D, Feany M. Tau phosphorylation sites work in concert to promote neurotoxicity in vivo. Mol Biol Cell. 2007;18:5060-8 pubmed
immunohistochemistry; human; fig 4A western blot; human; fig 1	Wiedau Pazos M, Wong E, Solomon E, Alarcon M, Geschwind D. Wnt-pathway activation during the early stage of neurodegeneration in FTDP-17 mice. Neurobiol Aging. 2009;30:14-21 pubmed
western blot; rat	Luo W, Dou F, Rodina A, Chip S, Kim J, Zhao Q, et al. Roles of heat-shock protein 90 in maintaining and facilitating the neurodegenerative phenotype in tauopathies. Proc Natl Acad Sci U S A. 2007;104:9511-6 pubmed
immunohistochemistry; mouse western blot; mouse	Caccamo A, Oddo S, Tran L, LaFerla F. Lithium reduces tau phosphorylation but not A beta or working memory deficits in a transgenic model with both plaques and tangles. Am J Pathol. 2007;170:1669-75 pubmed
western blot; human; 1:1,000	Green K, Martinez Coria H, Khashwji H, Hall E, Yurko Mauro K, Ellis L, et al. Dietary docosahexaenoic acid and docosapentaenoic acid ameliorate amyloid-beta and tau pathology via a mechanism involving presenilin 1 levels. J Neurosci. 2007;27:4385-95 pubmed
western blot; fruit fly ; 1:250; fig 2	Grammenoudi S, Kosmidis S, Skoulakis E. Cell type-specific processing of human Tau proteins in Drosophila. FEBS Lett. 2006;580:4602-6 pubmed
	Pradella D, Deflorian G, Pezzotta A, di Matteo A, Belloni E, Campolungo D, et al. A ligand-insensitive UNC5B splicing isoform regulates angiogenesis by promoting apoptosis. Nat Commun. 2021;12:4872 pubmed publisher
	Park J, Yoon J, Kwon D, Han M, Choi S, Park S, et al. Enhanced genome editing efficiency of CRISPR PLUS: Cas9 chimeric fusion proteins. Sci Rep. 2021;11:16199 pubmed publisher
	Mazzola S, Colombani C, Pizzamiglio G, Cannas S, Palestrini C, Costa E, et al. Do You Think I Am Living Well? A Four-Season Hair Cortisol Analysis on Leisure Horses in Different Housing and Management Conditions. Animals (Basel). 2021;11: pubmed publisher
	Villanueva Saz S, Giner J, Fernandez A, Lacasta D, Ortin A, Ramos J, et al. Absence of SARS-CoV-2 Antibodies in Natural Environment Exposure in Sheep in Close Contact with Humans. Animals (Basel). 2021;11: pubmed publisher
	Jeong S, Jung J, Kim M, de Groot A, Blanchard L, Ryu S, et al. Atypical Bacilliredoxin AbxC Plays a Role in Responding to Oxidative Stress in Radiation-Resistant Bacterium Deinococcus radiodurans. Antioxidants (Basel). 2021;10: pubmed publisher
	Lai Q, Guo M, Wu K, Liao Z, Guan D, Dong T, et al. Edible Bird's Nest, an Asian Health Food Supplement, Possesses Moisturizing Effect by Regulating Expression of Filaggrin in Skin Keratinocyte. Front Pharmacol. 2021;12:685982 pubmed publisher
	Holzner S, Bromberger S, Wenzina J, Neumüller K, Holper T, Petzelbauer P, et al. Phosphorylated cingulin localises GEF-H1 at tight junctions to protect vascular barriers in blood endothelial cells. J Cell Sci. 2021;: pubmed publisher
	Prelli Bozzo C, Nchioua R, Volcic M, Koepke L, Krüger J, Schütz D, et al. IFITM proteins promote SARS-CoV-2 infection and are targets for virus inhibition in vitro. Nat Commun. 2021;12:4584 pubmed publisher
	Tan Q, Li Y, Guo Y. Exercise Training Improves Functions of Endothelial Progenitor Cells in Patients with Metabolic Syndrome. Arq Bras Cardiol. 2021;117:108-117 pubmed publisher
	Song Z, Wang K, Sun Q, Zhang L, Li J, Li D, et al. High-Performance Ammonium Cobalt Phosphate Nanosheet Electrocatalyst for Alkaline Saline Water Oxidation. Adv Sci (Weinh). 2021;8:2100498 pubmed publisher
	Isiaku A, Zhang Z, Pazhakh V, Manley H, Thompson E, Fox L, et al. Transient, flexible gene editing in zebrafish neutrophils and macrophages for determination of cell-autonomous functions. Dis Model Mech. 2021;14: pubmed publisher
	Schroeder C, Tomlin S, Mejia Natividad I, Valenzuela J, Young J, Malik H. An actin-related protein that is most highly expressed in Drosophila testes is critical for embryonic development. elife. 2021;10: pubmed publisher
	Shaghaghi H, Cuevas Mora K, Para R, Tran C, Roque W, Robertson M, et al. A model of the aged lung epithelium in idiopathic pulmonary fibrosis. Aging (Albany NY). 2021;13:16922-16937 pubmed publisher
	Boehm V, Kueckelmann S, Gerbracht J, Kallabis S, Britto Borges T, Altmuller J, et al. SMG5-SMG7 authorize nonsense-mediated mRNA decay by enabling SMG6 endonucleolytic activity. Nat Commun. 2021;12:3965 pubmed publisher
	Kychygina A, Dall Osto M, Allen J, Cadoret J, Piras V, Pickett H, et al. Progerin impairs 3D genome organization and induces fragile telomeres by limiting the dNTP pools. Sci Rep. 2021;11:13195 pubmed publisher
	Garcia L, Tenev T, Newman R, Haich R, Liccardi G, John S, et al. Ubiquitylation of MLKL at lysine 219 positively regulates necroptosis-induced tissue injury and pathogen clearance. Nat Commun. 2021;12:3364 pubmed publisher
	Wang C, Rabadan Ros R, Martínez Redondo P, Ma Z, Shi L, Xue Y, et al. In vivo partial reprogramming of myofibers promotes muscle regeneration by remodeling the stem cell niche. Nat Commun. 2021;12:3094 pubmed publisher
	Wu D, Harrison D, Szasz T, Yeh C, Shentu T, Meliton A, et al. Single-cell metabolic imaging reveals a SLC2A3-dependent glycolytic burst in motile endothelial cells. Nat Metab. 2021;3:714-727 pubmed publisher
	Yan D, Franzini A, Pomicter A, Halverson B, Antelope O, Mason C, et al. SIRT5 IS A DRUGGABLE METABOLIC VULNERABILITY IN ACUTE MYELOID LEUKEMIA. Blood Cancer Discov. 2021;2:266-287 pubmed publisher
	Li D, Lin M, Rawle D, Jin H, Wu Z, Wang L, et al. Dengue virus-free defective interfering particles have potent and broad anti-dengue virus activity. Commun Biol. 2021;4:557 pubmed publisher
	Liu D, Song A, Qi X, van Vliet P, Xiao J, Xiong F, et al. Cohesin-protein Shugoshin-1 controls cardiac automaticity via HCN4 pacemaker channel. Nat Commun. 2021;12:2551 pubmed publisher
	Metwally D, Al Turaiki I, Altwaijry N, Alghamdi S, Alanazi A. Molecular Identification of Trypanosoma evansi Isolated from Arabian Camels (Camelus dromedarius) in Riyadh and Al-Qassim, Saudi Arabia. Animals (Basel). 2021;11: pubmed publisher
	Sun X, Zhang X, Ren X, Sun H, Wu L, Wang C, et al. Multiscale Co-reconstruction of Lung Architectures and Inhalable Materials Spatial Distribution. Adv Sci (Weinh). 2021;8:2003941 pubmed publisher
	LaMothe J, Khurana S, Tharmalingam S, Williamson C, Byrne C, Lees S, et al. Oxidative Stress Mediates the Fetal Programming of Hypertension by Glucocorticoids. Antioxidants (Basel). 2021;10: pubmed publisher
	Flees J, Emami N, GREENE E, Ganguly B, Dridi S. Phytogenic Water Additives Improve Broiler Growth Performance via Modulation of Intermediary Metabolism-Related Signaling Pathways. Animals (Basel). 2021;11: pubmed publisher
	Giner J, Villanueva Saz S, Tobajas A, Pérez M, Gonzalez A, Verde M, et al. SARS-CoV-2 Seroprevalence in Household Domestic Ferrets (Mustela putorius furo). Animals (Basel). 2021;11: pubmed publisher
	Lay A, Hale L, Stowell Connolly H, Pope R, Nair V, Ju W, et al. IGFBP-1 expression is reduced in human type 2 diabetic glomeruli and modulates β1-integrin/FAK signalling in human podocytes. Diabetologia. 2021;64:1690-1702 pubmed publisher
	Goldfarb A, Freeman K, Sahu R, Elagib K, Holy M, Arneja A, et al. Iron control of erythroid microtubule cytoskeleton as a potential target in treatment of iron-restricted anemia. Nat Commun. 2021;12:1645 pubmed publisher
	Miller L, Mukadam A, Durrant C, Vaysburd M, Katsinelos T, Tuck B, et al. Tau assemblies do not behave like independently acting prion-like particles in mouse neural tissue. Acta Neuropathol Commun. 2021;9:41 pubmed publisher
	McMurray L, Macdonald J, Ramakrishnan N, Zhao Y, Williamson D, Tietz O, et al. Synthesis and Assessment of Novel Probes for Imaging Tau Pathology in Transgenic Mouse and Rat Models. ACS Chem Neurosci. 2021;12:1885-1893 pubmed publisher
	Daniloski Z, Jordan T, Ilmain J, Guo X, Bhabha G, tenOever B, et al. The Spike D614G mutation increases SARS-CoV-2 infection of multiple human cell types. elife. 2021;10: pubmed publisher
	Laureau R, Dyatel A, Dursuk G, Brown S, Adeoye H, Yue J, et al. Meiotic Cells Counteract Programmed Retrotransposon Activation via RNA-Binding Translational Repressor Assemblies. Dev Cell. 2021;56:22-35.e7 pubmed publisher
	Kosek D, Hickman A, Ghirlando R, He S, Dyda F. Structures of ISCth4 transpososomes reveal the role of asymmetry in copy-out/paste-in DNA transposition. EMBO J. 2021;40:e105666 pubmed publisher
	Das R, Balmik A, Chinnathambi S. Melatonin Reduces GSK3β-Mediated Tau Phosphorylation, Enhances Nrf2 Nuclear Translocation and Anti-Inflammation. ASN Neuro. 2020;12:1759091420981204 pubmed publisher
	Patra T, Meyer K, Geerling L, Isbell T, Hoft D, Brien J, et al. SARS-CoV-2 spike protein promotes IL-6 trans-signaling by activation of angiotensin II receptor signaling in epithelial cells. PLoS Pathog. 2020;16:e1009128 pubmed publisher
	Salahudeen A, Choi S, Rustagi A, Zhu J, van Unen V, de la O S, et al. Progenitor identification and SARS-CoV-2 infection in human distal lung organoids. Nature. 2020;588:670-675 pubmed publisher
	Ma H, Jeppesen J, Jaenisch R. Human T Cells Expressing a CD19 CAR-T Receptor Provide Insights into Mechanisms of Human CD19-Positive β Cell Destruction. Cell Rep Med. 2020;1:100097 pubmed publisher
	Mao X, Tey S, Yeung C, Kwong E, Fung Y, Chung C, et al. Nidogen 1-Enriched Extracellular Vesicles Facilitate Extrahepatic Metastasis of Liver Cancer by Activating Pulmonary Fibroblasts to Secrete Tumor Necrosis Factor Receptor 1. Adv Sci (Weinh). 2020;7:2002157 pubmed publisher
	Massella E, Reid C, Cummins M, Anantanawat K, Zingali T, Serraino A, et al. Snapshot Study of Whole Genome Sequences of Escherichia coli from Healthy Companion Animals, Livestock, Wildlife, Humans and Food in Italy. Antibiotics (Basel). 2020;9: pubmed publisher
	Lee N, Kim S, Yu D, Woo E, Kim M, Seong G, et al. Aglycosylated antibody-producing mice for aglycosylated antibody-lectin coupled immunoassay for the quantification of tumor markers (ALIQUAT). Commun Biol. 2020;3:636 pubmed publisher
	Ni R, Chen Z, Gerez J, Shi G, Zhou Q, Riek R, et al. Detection of cerebral tauopathy in P301L mice using high-resolution large-field multifocal illumination fluorescence microscopy. Biomed Opt Express. 2020;11:4989-5002 pubmed publisher
	Asai Y, Matsumura R, Hasumi Y, Susumu H, Nagata K, Watanabe Y, et al. SET/TAF1 forms a distance-dependent feedback loop with Aurora B and Bub1 as a tension sensor at centromeres. Sci Rep. 2020;10:15653 pubmed publisher
	Costa G, Bradbury J, Tarannum N, Herbert S. RAB13 mRNA compartmentalisation spatially orients tissue morphogenesis. EMBO J. 2020;39:e106003 pubmed publisher
	Ramadhin J, Silva Moraes V, Norberg T, Harn D. Monoclonal Antibodies Generated against Glycoconjugates Recognize Chemical Linkers. Antibodies (Basel). 2020;9: pubmed publisher
	Bernard E, Fearns A, Bussi C, Santucci P, Peddie C, Lai R, et al. M. tuberculosis infection of human iPSC-derived macrophages reveals complex membrane dynamics during xenophagy evasion. J Cell Sci. 2020;134: pubmed publisher
	Al Jubury A, Kania P, Bygum A, Buchmann K. Temperature and light effects on Trichobilharzia szidati cercariae with implications for a risk analysis. Acta Vet Scand. 2020;62:54 pubmed publisher
	Rubab M, Oh D. Virulence Characteristics and Antibiotic Resistance Profiles of Shiga Toxin-Producing Escherichia coli Isolates from Diverse Sources. Antibiotics (Basel). 2020;9: pubmed publisher
	Hassebroek V, Park H, Pandey N, Lerbakken B, Aksenova V, Arnaoutov A, et al. PICH regulates the abundance and localization of SUMOylated proteins on mitotic chromosomes. Mol Biol Cell. 2020;31:2537-2556 pubmed publisher
	Pradal I, Esteban J, Mediero A, García Coca M, Aguilera Correa J. Contact Effect of a Methylobacteriumsp. Extract on Biofilm of a Mycobacteriumchimaera Strain Isolated from a 3T Heater-Cooler System. Antibiotics (Basel). 2020;9: pubmed publisher
	Salahudeen A, Choi S, Rustagi A, Zhu J, de la O S, Flynn R, et al. Progenitor identification and SARS-CoV-2 infection in long-term human distal lung organoid cultures. bioRxiv. 2020;: pubmed publisher
	Dominguez Meijide A, Vasili E, König A, Cima Omori M, Ibañez de Opakua A, Leonov A, et al. Effects of pharmacological modulators of α-synuclein and tau aggregation and internalization. Sci Rep. 2020;10:12827 pubmed publisher
	Valdés García A, Juárez Serrano N, Beltrán Sanahuja A, Garrigós M. Novel Antioxidant Packaging Films Based on Poly(ε-Caprolactone) and Almond Skin Extract: Development and Effect on the Oxidative Stability of Fried Almonds. Antioxidants (Basel). 2020;9: pubmed publisher
	Choi K, Koo B, Yoon B, Jung M, Yun H, Jeon B, et al. Overexpressed p32 localized in the endoplasmic reticulum and mitochondria negatively regulates calcium‑dependent endothelial nitric oxide synthase activit. Mol Med Rep. 2020;22:2395-2403 pubmed publisher
	Abdul Hamid N, Sadiq M, Ramanoon S, Mansor R, Watanabe M, Md Isa N, et al. Seroprevalence and Risk Factors of Toxoplasma gondii in Ruminant Meats from Wet Markets in Klang Valley and Abattoirs in Selangor, Malaysia. Animals (Basel). 2020;10: pubmed publisher
	Inde Z, Forcina G, Denton K, Dixon S. Kinetic Heterogeneity of Cancer Cell Fractional Killing. Cell Rep. 2020;32:107845 pubmed publisher
	Zhou T, Damsky W, Weizman O, McGeary M, Hartmann K, Rosen C, et al. IL-18BP is a secreted immune checkpoint and barrier to IL-18 immunotherapy. Nature. 2020;583:609-614 pubmed publisher
	Robinson K, Narasipura S, Wallace J, Ritz E, Al Harthi L. β-Catenin and TCFs/LEF signaling discordantly regulate IL-6 expression in astrocytes. Cell Commun Signal. 2020;18:93 pubmed publisher
	Humeau J, Leduc M, Cerrato G, Loos F, Kepp O, Kroemer G. Phosphorylation of eukaryotic initiation factor-2α (eIF2α) in autophagy. Cell Death Dis. 2020;11:433 pubmed publisher
	Roderer D, Bröcker F, Sitsel O, Kaplonek P, Leidreiter F, Seeberger P, et al. Glycan-dependent cell adhesion mechanism of Tc toxins. Nat Commun. 2020;11:2694 pubmed publisher
	Zhu G, Zhang L, Dan J, Zhu Q. Differential effects and mechanisms of local anesthetics on esophageal carcinoma cell migration, growth, survival and chemosensitivity. BMC Anesthesiol. 2020;20:126 pubmed publisher
	Dubey R, van Kerkhof P, Jordens I, Malinauskas T, Pusapati G, McKenna J, et al. R-spondins engage heparan sulfate proteoglycans to potentiate WNT signaling. elife. 2020;9: pubmed publisher
	Joshi V, Newman R, Pack M, Power K, Munro J, Okawa K, et al. Gp41-targeted antibodies restore infectivity of a fusion-deficient HIV-1 envelope glycoprotein. PLoS Pathog. 2020;16:e1008577 pubmed publisher
	Wang J, Wang Z, Yuan J, Wang J, Shen X. The positive feedback between ACSL4 expression and O-GlcNAcylation contributes to the growth and survival of hepatocellular carcinoma. Aging (Albany NY). 2020;12:7786-7800 pubmed publisher
	Humeau J, Sauvat A, Cerrato G, Xie W, Loos F, Iannantuoni F, et al. Inhibition of transcription by dactinomycin reveals a new characteristic of immunogenic cell stress. EMBO Mol Med. 2020;12:e11622 pubmed publisher
	Ghosh A, Rao V, Wisniewski V, Zigrossi A, Floss J, Koulen P, et al. Differential Activation of Glioprotective Intracellular Signaling Pathways in Primary Optic Nerve Head Astrocytes after Treatment with Different Classes of Antioxidants. Antioxidants (Basel). 2020;9: pubmed publisher
	Perli T, Moonen D, van den Broek M, Pronk J, Daran J. Adaptive Laboratory Evolution and Reverse Engineering of Single-Vitamin Prototrophies in Saccharomyces cerevisiae. Appl Environ Microbiol. 2020;86: pubmed publisher
	Jones M, Khodaverdian A, Quinn J, Chan M, Hussmann J, Wang R, et al. Inference of single-cell phylogenies from lineage tracing data using Cassiopeia. Genome Biol. 2020;21:92 pubmed publisher
	Samanas N, Engelhart E, Hoppins S. Defective nucleotide-dependent assembly and membrane fusion in Mfn2 CMT2A variants improved by Bax. Life Sci Alliance. 2020;3: pubmed publisher
	Vishnoi N, Dhanasekeran K, Chalfant M, Surovstev I, Khokha M, Lusk C. Differential turnover of Nup188 controls its levels at centrosomes and role in centriole duplication. J Cell Biol. 2020;219: pubmed publisher
	Rathore A, Iketani S, Wang P, Jia M, Sahi V, Ho D. CRISPR-based gene knockout screens reveal deubiquitinases involved in HIV-1 latency in two Jurkat cell models. Sci Rep. 2020;10:5350 pubmed publisher
	Pein M, Insua Rodríguez J, Hongu T, Riedel A, Meier J, Wiedmann L, et al. Metastasis-initiating cells induce and exploit a fibroblast niche to fuel malignant colonization of the lungs. Nat Commun. 2020;11:1494 pubmed publisher
	Adusumilli L, Facchinello N, Teh C, Busolin G, Le M, Yang H, et al. miR-7 Controls the Dopaminergic/Oligodendroglial Fate through Wnt/β-catenin Signaling Regulation. Cells. 2020;9: pubmed publisher
	Gasilina A, Premnauth G, Gurjar P, Biesiada J, Hegde S, Milewski D, et al. IODVA1, a guanidinobenzimidazole derivative, targets Rac activity and Ras-driven cancer models. PLoS ONE. 2020;15:e0229801 pubmed publisher
	Burton L, Scaife P, Paine S, Mellor H, Abernethy L, Littlewood P, et al. Hydrostatic pressure regulates CYP1A2 expression in human hepatocytes via a mechanosensitive aryl hydrocarbon receptor-dependent pathway. Am J Physiol Cell Physiol. 2020;318:C889-C902 pubmed publisher
	Castelli V, d Angelo M, Lombardi F, Alfonsetti M, Antonosante A, Catanesi M, et al. Effects of the probiotic formulation SLAB51 in in vitro and in vivo Parkinson's disease models. Aging (Albany NY). 2020;12:4641-4659 pubmed publisher
	Yang S, Adaway M, Du J, Huang S, Sun J, Bidwell J, et al. NMP4 regulates the innate immune response to influenza A virus infection. Mucosal Immunol. 2020;: pubmed publisher
	Ray J, de Boer C, Fulco C, Lareau C, Kanai M, Ulirsch J, et al. Prioritizing disease and trait causal variants at the TNFAIP3 locus using functional and genomic features. Nat Commun. 2020;11:1237 pubmed publisher
	Oda Y, Sugawara T, Fukata Y, Izumi Y, Otani T, Higashi T, et al. The extracellular domain of angulin-1 and palmitoylation of its cytoplasmic region are required for angulin-1 assembly at tricellular contacts. J Biol Chem. 2020;295:4289-4302 pubmed publisher
	Wang C, Qiao X, Zhang Z, Li C. MiR-128 promotes osteogenic differentiation of bone marrow mesenchymal stem cells in rat by targeting DKK2. Biosci Rep. 2020;40: pubmed publisher
	Tanaka H, Homma H, Fujita K, Kondo K, Yamada S, Jin X, et al. YAP-dependent necrosis occurs in early stages of Alzheimer's disease and regulates mouse model pathology. Nat Commun. 2020;11:507 pubmed publisher
	Jones S, King P, Antonescu C, Sugiyama M, Bhamra A, Surinova S, et al. Targeting of EGFR by a combination of antibodies mediates unconventional EGFR trafficking and degradation. Sci Rep. 2020;10:663 pubmed publisher
	Mandracchia B, Hua X, Guo C, Son J, Urner T, Jia S. Fast and accurate sCMOS noise correction for fluorescence microscopy. Nat Commun. 2020;11:94 pubmed publisher
	Lovejoy C, Takai K, Huh M, Picketts D, de Lange T. ATRX affects the repair of telomeric DSBs by promoting cohesion and a DAXX-dependent activity. PLoS Biol. 2020;18:e3000594 pubmed publisher
	Bosch J, Knight S, Kanca O, ZIRIN J, Yang Zhou D, Hu Y, et al. Use of the CRISPR-Cas9 System in Drosophila Cultured Cells to Introduce Fluorescent Tags into Endogenous Genes. Curr Protoc Mol Biol. 2020;130:e112 pubmed publisher
	Nguyen L, Montrasio F, Pattamatta A, Tusi S, Bardhi O, Meyer K, et al. Antibody Therapy Targeting RAN Proteins Rescues C9 ALS/FTD Phenotypes in C9orf72 Mouse Model. Neuron. 2020;105:645-662.e11 pubmed publisher
	Nogueira Lopez G, Padilla Arizmendi F, Inwood S, Lyne S, Steyaert J, Nieto Jacobo M, et al. TrichoGate: An Improved Vector System for a Large Scale of Functional Analysis of Trichoderma Genes. Front Microbiol. 2019;10:2794 pubmed publisher
	Chumarina M, Russ K, Azevedo C, Heuer A, Pihl M, Collin A, et al. Cellular alterations identified in pluripotent stem cell-derived midbrain spheroids generated from a female patient with progressive external ophthalmoplegia and parkinsonism who carries a novel variation (p.Q811R) in the POLG1 gene. Acta Neuropathol Commun. 2019;7:208 pubmed publisher
	Lund P, Chatterjee S, Daher M, Walter N. Protein unties the pseudoknot: S1-mediated unfolding of RNA higher order structure. Nucleic Acids Res. 2019;: pubmed publisher
	Shu C, Kaxon Rupp A, Collado J, Damoiseaux R, Crosbie R. Development of a high-throughput screen to identify small molecule enhancers of sarcospan for the treatment of Duchenne muscular dystrophy. Skelet Muscle. 2019;9:32 pubmed publisher
	Klingstedt T, Ghetti B, Holton J, Ling H, Nilsson K, Goedert M. Luminescent conjugated oligothiophenes distinguish between α-synuclein assemblies of Parkinson's disease and multiple system atrophy. Acta Neuropathol Commun. 2019;7:193 pubmed publisher
	Wang D, Zhang Q, Li F, Wang C, Yang C, Yu H. β-TrCP-mediated ubiquitination and degradation of Dlg5 regulates hepatocellular carcinoma cell proliferation. Cancer Cell Int. 2019;19:298 pubmed publisher
	Ma C, Wang X, Xu T, Yu X, Zhang S, Liu S, et al. Qingkailing injection ameliorates cerebral ischemia-reperfusion injury and modulates the AMPK/NLRP3 Inflammasome Signalling pathway. BMC Complement Altern Med. 2019;19:320 pubmed publisher
	Schwab N, Grenier K, Hazrati L. DNA repair deficiency and senescence in concussed professional athletes involved in contact sports. Acta Neuropathol Commun. 2019;7:182 pubmed publisher
	Schlegel K, Awwad K, Heym R, Holzinger D, Doell A, Barghorn S, et al. N368-Tau fragments generated by legumain are detected only in trace amount in the insoluble Tau aggregates isolated from AD brain. Acta Neuropathol Commun. 2019;7:177 pubmed publisher
	Ruan H, Liao Y, Ren Z, Mao L, Yao F, Yu P, et al. Single-cell reconstruction of differentiation trajectory reveals a critical role of ETS1 in human cardiac lineage commitment. BMC Biol. 2019;17:89 pubmed publisher
	Ziegler C, Dang L, Eisenhauer P, Kelly J, King B, Klaus J, et al. NEDD4 family ubiquitin ligases associate with LCMV Z's PPXY domain and are required for virus budding, but not via direct ubiquitination of Z. PLoS Pathog. 2019;15:e1008100 pubmed publisher
	Farmer J, Allard Chamard H, Sun N, Ahmad M, Bertocchi A, Mahajan V, et al. Induction of metabolic quiescence defines the transitional to follicular B cell switch. Sci Signal. 2019;12: pubmed publisher
	Freije C, Myhrvold C, Boehm C, Lin A, Welch N, Carter A, et al. Programmable Inhibition and Detection of RNA Viruses Using Cas13. Mol Cell. 2019;76:826-837.e11 pubmed publisher
	Bryan M, O Brien M, Nordham K, Rose D, Foshage A, Joshi P, et al. Acute manganese treatment restores defective autophagic cargo loading in Huntington's disease cell lines. Hum Mol Genet. 2019;28:3825-3841 pubmed publisher
	Buchwalter A, Schulte R, Tsai H, Capitanio J, Hetzer M. Selective clearance of the inner nuclear membrane protein emerin by vesicular transport during ER stress. elife. 2019;8: pubmed publisher
	Nagaraja S, Quezada M, Gillespie S, Arzt M, Lennon J, Woo P, et al. Histone Variant and Cell Context Determine H3K27M Reprogramming of the Enhancer Landscape and Oncogenic State. Mol Cell. 2019;76:965-980.e12 pubmed publisher
	Rimbault C, Maruthi K, Breillat C, Genuer C, Crespillo S, Puente Muñoz V, et al. Engineering selective competitors for the discrimination of highly conserved protein-protein interaction modules. Nat Commun. 2019;10:4521 pubmed publisher
	Neumann B, Baror R, Zhao C, SEGEL M, Dietmann S, Rawji K, et al. Metformin Restores CNS Remyelination Capacity by Rejuvenating Aged Stem Cells. Cell Stem Cell. 2019;25:473-485.e8 pubmed publisher
	Li T, Coan J, Krajewski K, Zhang L, Elias J, Strahl B, et al. Binding to medium and long chain fatty acyls is a common property of HEAT and ARM repeat modules. Sci Rep. 2019;9:14226 pubmed publisher
	Diprima M, Wang D, Tröster A, Maric D, Terrades García N, Ha T, et al. Identification of Eph receptor signaling as a regulator of autophagy and a therapeutic target in colorectal carcinoma. Mol Oncol. 2019;13:2441-2459 pubmed publisher
	Montalbano M, McAllen S, Sengupta U, Puangmalai N, Bhatt N, Ellsworth A, et al. Tau oligomers mediate aggregation of RNA-binding proteins Musashi1 and Musashi2 inducing Lamin alteration. Aging Cell. 2019;18:e13035 pubmed publisher
	Mancuso R, Fryatt G, Cleal M, Obst J, Pipi E, Monzón Sandoval J, et al. CSF1R inhibitor JNJ-40346527 attenuates microglial proliferation and neurodegeneration in P301S mice. Brain. 2019;142:3243-3264 pubmed publisher
	Panier S, Maric M, Hewitt G, Mason Osann E, Gali H, Dai A, et al. SLX4IP Antagonizes Promiscuous BLM Activity during ALT Maintenance. Mol Cell. 2019;76:27-43.e11 pubmed publisher
	Stavreva D, Garcia D, Fettweis G, Gudla P, Zaki G, Soni V, et al. Transcriptional Bursting and Co-bursting Regulation by Steroid Hormone Release Pattern and Transcription Factor Mobility. Mol Cell. 2019;75:1161-1177.e11 pubmed publisher
	Frikstad K, Molinari E, Thoresen M, Ramsbottom S, Hughes F, Letteboer S, et al. A CEP104-CSPP1 Complex Is Required for Formation of Primary Cilia Competent in Hedgehog Signaling. Cell Rep. 2019;28:1907-1922.e6 pubmed publisher
	Mendoza Elizalde S, Cortés Márquez A, Zúñiga G, Cerritos R, Valencia Mayoral P, Sánchez A, et al. Inference from the analysis of genetic structure of Helicobacter pylori strains isolates from two paediatric patients with recurrent infection. BMC Microbiol. 2019;19:184 pubmed publisher
	Rojas J, Reynolds N, Pike B, Espinoza N, Kuroiwa J, Jani V, et al. Distribution of Capsular Types of Campylobacter jejuni Isolates from Symptomatic and Asymptomatic Children in Peru. Am J Trop Med Hyg. 2019;101:541-548 pubmed publisher
	James C, Prabhakar A, Otoa R, Evans M, Wang X, Bristol M, et al. SAMHD1 Regulates Human Papillomavirus 16-Induced Cell Proliferation and Viral Replication during Differentiation of Keratinocytes. mSphere. 2019;4: pubmed publisher
	Kim D, Jung I, Kim D, Park S. Knockout of longevity gene Sirt1 in zebrafish leads to oxidative injury, chronic inflammation, and reduced life span. PLoS ONE. 2019;14:e0220581 pubmed publisher
	Min Z, Xiaomeng L, Zheng L, Yangge D, Xuejiao L, Longwei L, et al. Asymmetrical methyltransferase PRMT3 regulates human mesenchymal stem cell osteogenesis via miR-3648. Cell Death Dis. 2019;10:581 pubmed publisher
	Lee C, Shin H, Kimble J. Dynamics of Notch-Dependent Transcriptional Bursting in Its Native Context. Dev Cell. 2019;50:426-435.e4 pubmed publisher
	Ramos I, Smith G, Ruf Zamojski F, Martínez Romero C, Fribourg M, Carbajal E, et al. Innate Immune Response to Influenza Virus at Single-Cell Resolution in Human Epithelial Cells Revealed Paracrine Induction of Interferon Lambda 1. J Virol. 2019;93: pubmed publisher
	Kumar A, Birnbaum M, Moorthy B, Singh J, Palovcak A, Patel D, et al. Insertion/deletion-activated frame-shift fluorescence protein is a sensitive reporter for genomic DNA editing. BMC Genomics. 2019;20:609 pubmed publisher
	Gu W, Nowak W, Xie Y, Le Bras A, Hu Y, Deng J, et al. Single-Cell RNA-Sequencing and Metabolomics Analyses Reveal the Contribution of Perivascular Adipose Tissue Stem Cells to Vascular Remodeling. Arterioscler Thromb Vasc Biol. 2019;39:2049-2066 pubmed publisher
	Karges J, Jakubaszek M, Mari C, Zarschler K, Goud B, Stephan H, et al. Synthesis and Characterization of an Epidermal Growth Factor Receptor-Selective RuII Polypyridyl-Nanobody Conjugate as a Photosensitizer for Photodynamic Therapy. Chembiochem. 2019;: pubmed publisher
	Matsuda Lennikov M, Biancalana M, Zou J, Ravell J, Zheng L, Kanellopoulou C, et al. Magnesium transporter 1 (MAGT1) deficiency causes selective defects in N-linked glycosylation and expression of immune-response genes. J Biol Chem. 2019;294:13638-13656 pubmed publisher
	Wei Y, Zhou J, Wu J, Huang J. ERβ promotes Aβ degradation via the modulation of autophagy. Cell Death Dis. 2019;10:565 pubmed publisher
	Bhogaraju S, Bonn F, Mukherjee R, Adams M, Pfleiderer M, Galej W, et al. Inhibition of bacterial ubiquitin ligases by SidJ-calmodulin catalysed glutamylation. Nature. 2019;572:382-386 pubmed publisher
	Gan Q, Yao H, Na H, Ballance H, Tao Q, Leung L, et al. Effects of Amylin Against Amyloid-β-Induced Tauopathy and Synapse Loss in Primary Neurons. J Alzheimers Dis. 2019;70:1025-1040 pubmed publisher
	Grisard E, Coan M, Cesaratto L, Rigo I, Zandonà L, Paulitti A, et al. Sleeping beauty genetic screen identifies miR-23b::BTBD7 gene interaction as crucial for colorectal cancer metastasis. EBioMedicine. 2019;46:79-93 pubmed publisher
	Wang M, Fer N, Galeas J, Collisson E, Kim S, Sharib J, et al. Blockade of leukemia inhibitory factor as a therapeutic approach to KRAS driven pancreatic cancer. Nat Commun. 2019;10:3055 pubmed publisher
	Zhao N, Kamijo K, Fox P, Oda H, Morisaki T, Sato Y, et al. A genetically encoded probe for imaging nascent and mature HA-tagged proteins in vivo. Nat Commun. 2019;10:2947 pubmed publisher
	Neumann U, Derwenskus F, Flaiz Flister V, Schmid Staiger U, Hirth T, Bischoff S. Fucoxanthin, A Carotenoid Derived from Phaeodactylum tricornutum Exerts Antiproliferative and Antioxidant Activities In Vitro. Antioxidants (Basel). 2019;8: pubmed publisher
	El Bakkouri M, Kouidmi I, Wernimont A, Amani M, Hutchinson A, Loppnau P, et al. Structures of the cGMP-dependent protein kinase in malaria parasites reveal a unique structural relay mechanism for activation. Proc Natl Acad Sci U S A. 2019;116:14164-14173 pubmed publisher
	Hernández Díaz I, Pan J, Ricciardi C, Bai X, Ke J, White K, et al. Overexpression of Circulating Soluble Nogo-B Improves Diabetic Kidney Disease by Protecting the Vasculature. Diabetes. 2019;: pubmed publisher
	Phung B, Ciesla M, Sanna A, Guzzi N, Beneventi G, Cao Thi Ngoc P, et al. The X-Linked DDX3X RNA Helicase Dictates Translation Reprogramming and Metastasis in Melanoma. Cell Rep. 2019;27:3573-3586.e7 pubmed publisher
	Sloat S, Whitley B, Engelhart E, Hoppins S. Identification of a Mitofusin specificity region that confers unique activities to Mfn1 and Mfn2. Mol Biol Cell. 2019;:mbcE19050291 pubmed publisher
	Bing T, Shen L, Wang J, Wang L, Liu X, Zhang N, et al. Aptameric Probe Specifically Binding Protein Heterodimer Rather Than Monomers. Adv Sci (Weinh). 2019;6:1900143 pubmed publisher
	Zhang S, Zhao J, Zhang Y, Zhang Y, Cai F, Wang L, et al. Upregulation of MIF as a defense mechanism and a biomarker of Alzheimer's disease. Alzheimers Res Ther. 2019;11:54 pubmed publisher
	Verschuuren M, Verstraelen P, Garcia Díaz Barriga G, Cilissen I, Coninx E, Verslegers M, et al. High-throughput microscopy exposes a pharmacological window in which dual leucine zipper kinase inhibition preserves neuronal network connectivity. Acta Neuropathol Commun. 2019;7:6 pubmed publisher
	Matsumoto S, Cavadini S, Bunker R, Grand R, Potenza A, Rabl J, et al. DNA damage detection in nucleosomes involves DNA register shifting. Nature. 2019;: pubmed publisher
	Muniraju M, Mutsvunguma L, Foley J, Escalante G, Rodriguez E, Nabiee R, et al. Kaposi Sarcoma-associated Herpesvirus Glycoprotein H is Indispensable for Infection of Epithelial, Endothelial, and Fibroblast Cell Types. J Virol. 2019;: pubmed publisher
	Silva B, Pentz R, Figueira A, Arora R, Lee Y, Hodson C, et al. FANCM limits ALT activity by restricting telomeric replication stress induced by deregulated BLM and R-loops. Nat Commun. 2019;10:2253 pubmed publisher
	Rawlinson T, Barber N, Mohring F, Cho J, Kosaisavee V, Gerard S, et al. Structural basis for inhibition of Plasmodium vivax invasion by a broadly neutralizing vaccine-induced human antibody. Nat Microbiol. 2019;: pubmed publisher
	Terreros Roncal J, Flor García M, Moreno Jiménez E, Pallas Bazarra N, Rabano A, Sah N, et al. Activity-dependent reconnection of adult-born dentate granule cells in a mouse model of frontotemporal dementia. J Neurosci. 2019;: pubmed publisher
	García Rodríguez F, Neira J, Marcia M, Molina Sánchez M, Toro N. A group II intron-encoded protein interacts with the cellular replicative machinery through the β-sliding clamp. Nucleic Acids Res. 2019;47:7605-7617 pubmed publisher
	Zavodszky E, Hegde R. Misfolded GPI-anchored proteins are escorted through the secretory pathway by ER-derived factors. elife. 2019;8: pubmed publisher
	Du Y, Duc N, Rasmussen S, Hilger D, Kubiak X, Wang L, et al. Assembly of a GPCR-G Protein Complex. Cell. 2019;177:1232-1242.e11 pubmed publisher
	Soday L, Lu Y, Albarnaz J, Davies C, Antrobus R, Smith G, et al. Quantitative Temporal Proteomic Analysis of Vaccinia Virus Infection Reveals Regulation of Histone Deacetylases by an Interferon Antagonist. Cell Rep. 2019;27:1920-1933.e7 pubmed publisher
	Nagamura R, Fukuda M, Kawamoto A, Matoba K, Dohmae N, Ishitani R, et al. Structural basis for oligomerization of the prokaryotic peptide transporter PepTSo2. Acta Crystallogr F Struct Biol Commun. 2019;75:348-358 pubmed publisher
	Mclaurin J, Weiner O. Multiple sources of signal amplification within the B-cell Ras/MAPK pathway. Mol Biol Cell. 2019;30:1610-1620 pubmed publisher
	Teixeira L, Fujiki R, Souza C, Souza C, Mismetti M, Artigiane Neto R, et al. Oxidative stress assessment in intestine of newborn rats submitted to hypoxia and reoxygenation with tadalafil. Acta Cir Bras. 2019;34:e201900407 pubmed publisher
	Zhao X, Tsuji K, Hymel D, Burke T. Development of Highly Selective 1,2,3-Triazole-containing Peptidic Polo-like Kinase 1 Polo-box Domain-binding Inhibitors. Molecules. 2019;24: pubmed publisher
	Madrigal Carrillo E, Díaz Tufinio C, Santamaría Suárez H, Arciniega M, Torres Larios A. A screening platform to monitor RNA processing and protein-RNA interactions in ribonuclease P uncovers a small molecule inhibitor. Nucleic Acids Res. 2019;47:6425-6438 pubmed publisher
	Shi Y, Gao W, Lytle N, Huang P, Yuan X, Dann A, et al. Targeting LIF-mediated paracrine interaction for pancreatic cancer therapy and monitoring. Nature. 2019;569:131-135 pubmed publisher
	Huang X, Xue H, Ma J, Zhang Y, Zhang J, Liu Y, et al. Salidroside ameliorates Adriamycin nephropathy in mice by inhibiting β-catenin activity. J Cell Mol Med. 2019;23:4443-4453 pubmed publisher
	McHugh B, Wang R, Li H, Beaumont P, Kells R, Stevens H, et al. Cathelicidin is a "fire alarm", generating protective NLRP3-dependent airway epithelial cell inflammatory responses during infection with Pseudomonas aeruginosa. PLoS Pathog. 2019;15:e1007694 pubmed publisher
	Regalado Reyes M, Furcila D, Hernandez F, Avila J, DeFelipe J, León Espinosa G. Phospho-Tau Changes in the Human CA1 During Alzheimer's Disease Progression. J Alzheimers Dis. 2019;69:277-288 pubmed publisher
	Lytle N, Ferguson L, Rajbhandari N, Gilroy K, Fox R, Deshpande A, et al. A Multiscale Map of the Stem Cell State in Pancreatic Adenocarcinoma. Cell. 2019;177:572-586.e22 pubmed publisher
	Engelhart E, Hoppins S. A catalytic domain variant of mitofusin requiring a wildtype paralog for function uncouples mitochondrial outer-membrane tethering and fusion. J Biol Chem. 2019;294:8001-8014 pubmed publisher
	Colin York H, Javanmardi Y, Skamrahl M, Kumari S, Chang V, Khuon S, et al. Cytoskeletal Control of Antigen-Dependent T Cell Activation. Cell Rep. 2019;26:3369-3379.e5 pubmed publisher
	Shapson Coe A, Valeiras B, Wall C, Rada C. Aicardi-Goutières Syndrome associated mutations of RNase H2B impair its interaction with ZMYM3 and the CoREST histone-modifying complex. PLoS ONE. 2019;14:e0213553 pubmed publisher
	Al Salam S, Aburawi E, Al Hammadi S, Dhanasekaran S, Shafiuallah M, Yasin J, et al. Cellular and Immunohistochemical Changes in Anaphylactic Shock Induced in the Ovalbumin-Sensitized Wistar Rat Model. Biomolecules. 2019;9: pubmed publisher
	Marcandalli J, Fiala B, Ols S, Perotti M, De van der Schueren W, Snijder J, et al. Induction of Potent Neutralizing Antibody Responses by a Designed Protein Nanoparticle Vaccine for Respiratory Syncytial Virus. Cell. 2019;176:1420-1431.e17 pubmed publisher
	Unterhauser K, Pöltl L, Schneditz G, Kienesberger S, Glabonjat R, Kitsera M, et al. Klebsiella oxytoca enterotoxins tilimycin and tilivalline have distinct host DNA-damaging and microtubule-stabilizing activities. Proc Natl Acad Sci U S A. 2019;116:3774-3783 pubmed publisher
	Nakamura K, Saredi G, Becker J, Foster B, Nguyen N, Beyer T, et al. H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids. Nat Cell Biol. 2019;21:311-318 pubmed publisher
	Trouillet A, Keller M, Weiss J, Leinders Zufall T, Birnbaumer L, Zufall F, et al. Central role of G protein Gαi2 and Gαi2+ vomeronasal neurons in balancing territorial and infant-directed aggression of male mice. Proc Natl Acad Sci U S A. 2019;116:5135-5143 pubmed publisher
	Wagner E, Qerqez A, Stevens C, Nguyen A, Delidakis G, Maynard J. Human cytomegalovirus-specific T-cell receptor engineered for high affinity and soluble expression using mammalian cell display. J Biol Chem. 2019;294:5790-5804 pubmed publisher
	Moti N, Yu J, Boncompain G, Perez F, Virshup D. Wnt traffic from endoplasmic reticulum to filopodia. PLoS ONE. 2019;14:e0212711 pubmed publisher
	Dorsey B, Huang L, MONDRAGON A. Structural organization of a Type III-A CRISPR effector subcomplex determined by X-ray crystallography and cryo-EM. Nucleic Acids Res. 2019;47:3765-3783 pubmed publisher
	Herb M, Gluschko A, Wiegmann K, Farid A, Wolf A, Utermöhlen O, et al. Mitochondrial reactive oxygen species enable proinflammatory signaling through disulfide linkage of NEMO. Sci Signal. 2019;12: pubmed publisher
	Foggetti G, Ottaggio L, Russo D, Mazzitelli C, Monti P, Degan P, et al. Autophagy induced by SAHA affects mutant P53 degradation and cancer cell survival. Biosci Rep. 2019;39: pubmed publisher
	Folk W, Kumari A, Iwasaki T, Pyndiah S, Johnson J, Cassimere E, et al. Loss of the tumor suppressor BIN1 enables ATM Ser/Thr kinase activation by the nuclear protein E2F1 and renders cancer cells resistant to cisplatin. J Biol Chem. 2019;294:5700-5719 pubmed publisher
	Bazzone L, King M, Mackay C, Kyawe P, Meraner P, LINDSTROM D, et al. A Disintegrin and Metalloproteinase 9 Domain (ADAM9) Is a Major Susceptibility Factor in the Early Stages of Encephalomyocarditis Virus Infection. MBio. 2019;10: pubmed publisher
	Yin C, Zhu B, Zhang T, Liu T, Chen S, Liu Y, et al. Pharmacological Targeting of STK19 Inhibits Oncogenic NRAS-Driven Melanomagenesis. Cell. 2019;176:1113-1127.e16 pubmed publisher
	Kozminsky M, Fouladdel S, Chung J, Wang Y, Smith D, Alva A, et al. Detection of CTC Clusters and a Dedifferentiated RNA-Expression Survival Signature in Prostate Cancer. Adv Sci (Weinh). 2019;6:1801254 pubmed publisher
	Jiménez M, Urtasun R, Elizalde M, Azkona M, Latasa M, Uriarte I, et al. Splicing events in the control of genome integrity: role of SLU7 and truncated SRSF3 proteins. Nucleic Acids Res. 2019;47:3450-3466 pubmed publisher
	Ueda S, Cordeiro I, Moriyama Y, Nishimori C, Kai K, Yu R, et al. Cux2 refines the forelimb field by controlling expression of Raldh2 and Hox genes. Biol Open. 2019;8: pubmed publisher
	Paonessa F, Evans L, Solanki R, Larrieu D, Wray S, Hardy J, et al. Microtubules Deform the Nuclear Membrane and Disrupt Nucleocytoplasmic Transport in Tau-Mediated Frontotemporal Dementia. Cell Rep. 2019;26:582-593.e5 pubmed publisher
	Meng F, Kassa T, Strader M, Soman J, Olson J, Alayash A. Substitutions in the β subunits of sickle-cell hemoglobin improve oxidative stability and increase the delay time of sickle-cell fiber formation. J Biol Chem. 2019;294:4145-4159 pubmed publisher
	Zhang S, Zhang H, Ghia E, Huang J, Wu L, Zhang J, et al. Inhibition of chemotherapy resistant breast cancer stem cells by a ROR1 specific antibody. Proc Natl Acad Sci U S A. 2019;116:1370-1377 pubmed publisher
	Masiulis S, Desai R, Uchański T, Serna Martin I, Laverty D, Karia D, et al. GABAA receptor signalling mechanisms revealed by structural pharmacology. Nature. 2019;565:454-459 pubmed publisher
	McCaughey J, Stevenson N, Cross S, Stephens D. ER-to-Golgi trafficking of procollagen in the absence of large carriers. J Cell Biol. 2019;218:929-948 pubmed publisher
	Janssen A, Colmenares S, Lee T, Karpen G. Timely double-strand break repair and pathway choice in pericentromeric heterochromatin depend on the histone demethylase dKDM4A. Genes Dev. 2019;33:103-115 pubmed publisher
	Strehlow V, Heyne H, Vlaskamp D, Marwick K, Rudolf G, de Bellescize J, et al. GRIN2A-related disorders: genotype and functional consequence predict phenotype. Brain. 2019;142:80-92 pubmed publisher
	Belfiore R, Rodin A, Ferreira E, Velázquez R, Branca C, Caccamo A, et al. Temporal and regional progression of Alzheimer's disease-like pathology in 3xTg-AD mice. Aging Cell. 2019;18:e12873 pubmed publisher
	Bajzikova M, Kovarova J, Coelho A, Boukalova S, Oh S, Rohlenova K, et al. Reactivation of Dihydroorotate Dehydrogenase-Driven Pyrimidine Biosynthesis Restores Tumor Growth of Respiration-Deficient Cancer Cells. Cell Metab. 2019;29:399-416.e10 pubmed publisher
	Liu N, Luo J, Kuang D, Xu S, Duan Y, Xia Y, et al. Lactate inhibits ATP6V0d2 expression in tumor-associated macrophages to promote HIF-2α-mediated tumor progression. J Clin Invest. 2019;129:631-646 pubmed publisher
	Nam W, Choi Y. In vitro generation of tau aggregates conformationally distinct from parent tau seeds of Alzheimer's brain. Prion. 2019;13:1-12 pubmed publisher
	Godovikova V, Goetting Minesky M, Timm J, Fenno J. Immunotopological Analysis of the Treponema denticola Major Surface Protein (Msp). J Bacteriol. 2019;201: pubmed publisher
	Zeng L, Burne R. Essential Roles of the sppRA Fructose-Phosphate Phosphohydrolase Operon in Carbohydrate Metabolism and Virulence Expression by Streptococcus mutans. J Bacteriol. 2019;201: pubmed publisher
	Goya Grocin A, Serwa R, Morales Sanfrutos J, Ritzefeld M, Tate E. Whole Proteome Profiling of N-Myristoyltransferase Activity and Inhibition Using Sortase A. Mol Cell Proteomics. 2019;18:115-126 pubmed publisher
	Jansing J, Sack M, Augustine S, Fischer R, Bortesi L. CRISPR/Cas9-mediated knockout of six glycosyltransferase genes in Nicotiana benthamiana for the production of recombinant proteins lacking β-1,2-xylose and core α-1,3-fucose. Plant Biotechnol J. 2019;17:350-361 pubmed publisher
	Raikwar S, Thangavel R, Dubova I, Selvakumar G, Ahmed M, Kempuraj D, et al. Targeted Gene Editing of Glia Maturation Factor in Microglia: a Novel Alzheimer's Disease Therapeutic Target. Mol Neurobiol. 2019;56:378-393 pubmed publisher
	Bagheri H, Friedman H, Shao H, Chong Y, Lo C, Emran F, et al. TIE: A Method to Electroporate Long DNA Templates into Preimplantation Embryos for CRISPR-Cas9 Gene Editing. CRISPR J. 2018;1:223-229 pubmed publisher
	Geddes B, Mendoza Suárez M, Poole P. A Bacterial Expression Vector Archive (BEVA) for Flexible Modular Assembly of Golden Gate-Compatible Vectors. Front Microbiol. 2018;9:3345 pubmed publisher
	den Haan J, Morrema T, Verbraak F, de Boer J, Scheltens P, Rozemuller A, et al. Amyloid-beta and phosphorylated tau in post-mortem Alzheimer's disease retinas. Acta Neuropathol Commun. 2018;6:147 pubmed publisher
	Zhou S, Dodia C, Feinstein S, Harper S, Forman H, Speicher D, et al. Oxidation of Peroxiredoxin 6 in the Presence of GSH Increases its Phospholipase A₂ Activity at Cytoplasmic pH. Antioxidants (Basel). 2018;8: pubmed publisher
	Geng R, Furness D, Muraleedharan C, Zhang J, Dabdoub A, Lin V, et al. The microRNA-183/96/182 Cluster is Essential for Stereociliary Bundle Formation and Function of Cochlear Sensory Hair Cells. Sci Rep. 2018;8:18022 pubmed publisher
	Renna L, Stefano G, Slabaugh E, Wormsbaecher C, Sulpizio A, Zienkiewicz K, et al. TGNap1 is required for microtubule-dependent homeostasis of a subpopulation of the plant trans-Golgi network. Nat Commun. 2018;9:5313 pubmed publisher
	Jayathilaka D, Gomes L, Jeewandara C, Jayarathna G, Herath D, Perera P, et al. Role of NS1 antibodies in the pathogenesis of acute secondary dengue infection. Nat Commun. 2018;9:5242 pubmed publisher
	Bracha D, Walls M, Wei M, Zhu L, Kurian M, Avalos J, et al. Mapping Local and Global Liquid Phase Behavior in Living Cells Using Photo-Oligomerizable Seeds. Cell. 2018;175:1467-1480.e13 pubmed publisher
	Romero Molina C, Navarro V, Sanchez Varo R, Jimenez S, Fernandez Valenzuela J, Sanchez Mico M, et al. Distinct Microglial Responses in Two Transgenic Murine Models of TAU Pathology. Front Cell Neurosci. 2018;12:421 pubmed publisher
	Lewis T, Kwon S, Lee A, SHAW R, Polleux F. MFF-dependent mitochondrial fission regulates presynaptic release and axon branching by limiting axonal mitochondria size. Nat Commun. 2018;9:5008 pubmed publisher
	Chen Y, Dolt K, Kriek M, Baker T, Downey P, Drummond N, et al. Engineering synucleinopathy-resistant human dopaminergic neurons by CRISPR-mediated deletion of the SNCA gene. Eur J Neurosci. 2018;: pubmed publisher
	Ebrahim N, Ahmed I, Hussien N, Dessouky A, Farid A, Elshazly A, et al. Mesenchymal Stem Cell-Derived Exosomes Ameliorated Diabetic Nephropathy by Autophagy Induction through the mTOR Signaling Pathway. Cells. 2018;7: pubmed publisher
	Mikaeili H, Sandi M, Bayot A, Al Mahdawi S, Pook M. FAST-1 antisense RNA epigenetically alters FXN expression. Sci Rep. 2018;8:17217 pubmed publisher
	Abdullah A, Zhang M, Frugier T, Bedoui S, Taylor J, Crack P. STING-mediated type-I interferons contribute to the neuroinflammatory process and detrimental effects following traumatic brain injury. J Neuroinflammation. 2018;15:323 pubmed publisher
	Qian Y, Zhang J, Zhou X, Yi R, Mu J, Long X, et al. Lactobacillus plantarum CQPC11 Isolated from Sichuan Pickled Cabbages Antagonizes d-galactose-Induced Oxidation and Aging in Mice. Molecules. 2018;23: pubmed publisher
	Ernst A, Syed S, Zaki O, Bottanelli F, Zheng H, Hacke M, et al. S-Palmitoylation Sorts Membrane Cargo for Anterograde Transport in the Golgi. Dev Cell. 2018;47:479-493.e7 pubmed publisher
	Rosenberg R, Fu M, Lambracht Washington D. Active full-length DNA Aβ42 immunization in 3xTg-AD mice reduces not only amyloid deposition but also tau pathology. Alzheimers Res Ther. 2018;10:115 pubmed publisher
	Dias J, Boulouis C, Gorin J, van den Biggelaar R, Lal K, Gibbs A, et al. The CD4-CD8- MAIT cell subpopulation is a functionally distinct subset developmentally related to the main CD8+ MAIT cell pool. Proc Natl Acad Sci U S A. 2018;115:E11513-E11522 pubmed publisher
	Kang S, Lee S, Kim J, Kim J, Kim S, Son Y, et al. Chronic Treatment with Combined Chemotherapeutic Agents Affects Hippocampal Micromorphometry and Function in Mice, Independently of Neuroinflammation. Exp Neurobiol. 2018;27:419-436 pubmed publisher
	Katanosaka K, Takatsu S, Mizumura K, Naruse K, Katanosaka Y. TRPV2 is required for mechanical nociception and the stretch-evoked response of primary sensory neurons. Sci Rep. 2018;8:16782 pubmed publisher
	Banda N, Desai D, Scheinman R, Pihl R, Sekine H, Fujita T, et al. Targeting of Liver Mannan-Binding Lectin-Associated Serine Protease-3 with RNA Interference Ameliorates Disease in a Mouse Model of Rheumatoid Arthritis. Immunohorizons. 2018;2:274-295 pubmed publisher
	D Alessandro M, Richard M, Stigloher C, Gache V, Boulin T, Richmond J, et al. CRELD1 is an evolutionarily-conserved maturational enhancer of ionotropic acetylcholine receptors. elife. 2018;7: pubmed publisher
	Bernal Sierra Y, Rost B, Pofahl M, Fernandes A, Kopton R, Moser S, et al. Potassium channel-based optogenetic silencing. Nat Commun. 2018;9:4611 pubmed publisher
	Hara H, Seregin S, Yang D, Fukase K, Chamaillard M, Alnemri E, et al. The NLRP6 Inflammasome Recognizes Lipoteichoic Acid and Regulates Gram-Positive Pathogen Infection. Cell. 2018;175:1651-1664.e14 pubmed publisher
	Jayawardena N, Burga L, Easingwood R, Takizawa Y, Wolf M, Bostina M. Structural basis for anthrax toxin receptor 1 recognition by Seneca Valley Virus. Proc Natl Acad Sci U S A. 2018;115:E10934-E10940 pubmed publisher
	Wall J, Williams A, Foster J, Richey T, Stuckey A, Macy S, et al. Bifunctional amyloid-reactive peptide promotes binding of antibody 11-1F4 to diverse amyloid types and enhances therapeutic efficacy. Proc Natl Acad Sci U S A. 2018;115:E10839-E10848 pubmed publisher
	Kirkwood N, Monchen J, Crisp R, Grimaldi G, Bergstein H, du Fossé I, et al. Finding and Fixing Traps in II-VI and III-V Colloidal Quantum Dots: The Importance of Z-Type Ligand Passivation. J Am Chem Soc. 2018;140:15712-15723 pubmed publisher
	Koo B, Hwang H, Yi B, Lim H, Jeon B, Hoe K, et al. Arginase II Contributes to the Ca2+/CaMKII/eNOS Axis by Regulating Ca2+ Concentration Between the Cytosol and Mitochondria in a p32-Dependent Manner. J Am Heart Assoc. 2018;7:e009579 pubmed publisher
	Nunes N, Kim S, Sundby M, Chandran P, Burks S, Paz A, et al. Temporal clinical, proteomic, histological and cellular immune responses of dextran sulfate sodium-induced acute colitis. World J Gastroenterol. 2018;24:4341-4355 pubmed publisher
	Blanco Suarez E, Liu T, Kopelevich A, Allen N. Astrocyte-Secreted Chordin-like 1 Drives Synapse Maturation and Limits Plasticity by Increasing Synaptic GluA2 AMPA Receptors. Neuron. 2018;100:1116-1132.e13 pubmed publisher
	Ganassi M, Badodi S, Ortuste Quiroga H, Zammit P, Hinits Y, Hughes S. Myogenin promotes myocyte fusion to balance fibre number and size. Nat Commun. 2018;9:4232 pubmed publisher
	Abreu Mota T, Hagen K, Cooper K, Jahrling P, Tan G, Wirblich C, et al. Non-neutralizing antibodies elicited by recombinant Lassa-Rabies vaccine are critical for protection against Lassa fever. Nat Commun. 2018;9:4223 pubmed publisher
	Chatterjee S, Cassel R, Schneider Anthony A, Merienne K, Cosquer B, Tzeplaeff L, et al. Reinstating plasticity and memory in a tauopathy mouse model with an acetyltransferase activator. EMBO Mol Med. 2018;10: pubmed publisher
	Kistler K, Trcek T, Hurd T, Chen R, Liang F, Sall J, et al. Phase transitioned nuclear Oskar promotes cell division of Drosophila primordial germ cells. elife. 2018;7: pubmed publisher
	Yan Y, Acevedo M, Mignacca L, Desjardins P, Scott N, Imane R, et al. The sequence features that define efficient and specific hAGO2-dependent miRNA silencing guides. Nucleic Acids Res. 2018;46:8181-8196 pubmed publisher
	Sahenk Z, Yalvac M, Amornvit J, Arnold W, Chen L, Shontz K, et al. Efficacy of exogenous pyruvate in TremblerJ mouse model of Charcot-Marie-Tooth neuropathy. Brain Behav. 2018;8:e01118 pubmed publisher
	Pan H, Palekar R, Hou K, Bacon J, Yan H, Springer L, et al. Anti-JNK2 peptide-siRNA nanostructures improve plaque endothelium and reduce thrombotic risk in atherosclerotic mice. Int J Nanomedicine. 2018;13:5187-5205 pubmed publisher
	Gennaro V, Stanek T, Peck A, Sun Y, Wang F, Qie S, et al. Control of CCND1 ubiquitylation by the catalytic SAGA subunit USP22 is essential for cell cycle progression through G1 in cancer cells. Proc Natl Acad Sci U S A. 2018;115:E9298-E9307 pubmed publisher
	Guo M, Haakonsen D, Zeng W, Schumacher M, Laub M. A Bacterial Chromosome Structuring Protein Binds Overtwisted DNA to Stimulate Type II Topoisomerases and Enable DNA Replication. Cell. 2018;175:583-597.e23 pubmed publisher
	Amilon K, Cortes Araya Y, Moore B, Lee S, Lillico S, Breton A, et al. Generation of Functional Myocytes from Equine Induced Pluripotent Stem Cells. Cell Reprogram. 2018;20:275-281 pubmed publisher
	Razavi P, Chang M, Xu G, Bandlamudi C, Ross D, VASAN N, et al. The Genomic Landscape of Endocrine-Resistant Advanced Breast Cancers. Cancer Cell. 2018;34:427-438.e6 pubmed publisher
	Mahlab Aviv S, Boulos A, Peretz A, Eliyahu T, Carmel L, Sperling R, et al. Small RNA sequences derived from pre-microRNAs in the supraspliceosome. Nucleic Acids Res. 2018;46:11014-11029 pubmed publisher
	Helsen N, Vervoort T, Vandenbossche J, Lenz O, Monshouwer M, Pauwels F, et al. Effect of Plasma Protein Binding on the Anti-Hepatitis B Virus Activity and Pharmacokinetic Properties of NVR 3-778. Antimicrob Agents Chemother. 2018;62: pubmed publisher
	Xu J, Zhu Y. A rapid in vitro method to flip back the double-floxed inverted open reading frame in a plasmid. BMC Biotechnol. 2018;18:52 pubmed publisher
	Correnti J, Gottshall L, Lin A, Williams B, Oranu A, Beck J, et al. Ethanol and C2 ceramide activate fatty acid oxidation in human hepatoma cells. Sci Rep. 2018;8:12923 pubmed publisher
	Wu Q, Lin Y, Gu J, Sigurdsson E. Dynamic assessment of tau immunotherapies in the brains of live animals by two-photon imaging. EBioMedicine. 2018;35:270-278 pubmed publisher
	Chiasson MacKenzie C, Morris Z, Liu C, Bradford W, Koorman T, McClatchey A. Merlin/ERM proteins regulate growth factor-induced macropinocytosis and receptor recycling by organizing the plasma membrane:cytoskeleton interface. Genes Dev. 2018;32:1201-1214 pubmed publisher
	Scott K, Schormans A, Pacoli K, de Oliveira C, Allman B, Schmid S. Altered Auditory Processing, Filtering, and Reactivity in the Cntnap2 Knock-Out Rat Model for Neurodevelopmental Disorders. J Neurosci. 2018;38:8588-8604 pubmed publisher
	Ho J, Hendi A. Recent trends in life expectancy across high income countries: retrospective observational study. BMJ. 2018;362:k2562 pubmed publisher
	Abraham A, Schattauer S, Reichard K, Cohen J, Fontaine H, Song A, et al. Estrogen Regulation of GRK2 Inactivates Kappa Opioid Receptor Signaling Mediating Analgesia, But Not Aversion. J Neurosci. 2018;38:8031-8043 pubmed publisher
	Bocca C, Kane M, Veyrat Durebex C, Chupin S, Alban J, Kouassi Nzoughet J, et al. The Metabolomic Bioenergetic Signature of Opa1-Disrupted Mouse Embryonic Fibroblasts Highlights Aspartate Deficiency. Sci Rep. 2018;8:11528 pubmed publisher
	Liu P, Fu X, Zhu J. Juvenile hormone-regulated alternative splicing of the taiman gene primes the ecdysteroid response in adult mosquitoes. Proc Natl Acad Sci U S A. 2018;115:E7738-E7747 pubmed publisher
	Higgins D, Young M, Tremaine M, Sardi M, Fletcher J, Agnew M, et al. Natural Variation in the Multidrug Efflux Pump SGE1 Underlies Ionic Liquid Tolerance in Yeast. Genetics. 2018;210:219-234 pubmed publisher
	Omsland M, Pise Masison C, Fujikawa D, Galli V, Fenizia C, Parks R, et al. Inhibition of Tunneling Nanotube (TNT) Formation and Human T-cell Leukemia Virus Type 1 (HTLV-1) Transmission by Cytarabine. Sci Rep. 2018;8:11118 pubmed publisher
	Alcaino C, Knutson K, Treichel A, Yildiz G, Strege P, Linden D, et al. A population of gut epithelial enterochromaffin cells is mechanosensitive and requires Piezo2 to convert force into serotonin release. Proc Natl Acad Sci U S A. 2018;115:E7632-E7641 pubmed publisher
	Kim H, Tiwari A, Hwang E, Cho Y, Hwang H, Bak S, et al. FeIn2S4 Nanocrystals: A Ternary Metal Chalcogenide Material for Ambipolar Field-Effect Transistors. Adv Sci (Weinh). 2018;5:1800068 pubmed publisher
	Ruedas J, Arnold C, Palacios G, Connor J. Growth-Adaptive Mutations in the Ebola Virus Makona Glycoprotein Alter Different Steps in the Virus Entry Pathway. J Virol. 2018;92: pubmed publisher
	Hartana C, Ahlén Bergman E, Broome A, Berglund S, Johansson M, Alamdari F, et al. Tissue-resident memory T cells are epigenetically cytotoxic with signs of exhaustion in human urinary bladder cancer. Clin Exp Immunol. 2018;194:39-53 pubmed publisher
	Eriksen A, Eliasen R, Oswald J, Kempen P, Melander F, Andresen T, et al. Multifarious Biologic Loaded Liposomes that Stimulate the Mammalian Target of Rapamycin Signaling Pathway Show Retina Neuroprotection after Retina Damage. ACS Nano. 2018;12:7497-7508 pubmed publisher
	Zhang S, Pei M, Li Z, Li H, Liu Y, Li J. Double-negative feedback interaction between DNA methyltransferase 3A and microRNA-145 in the Warburg effect of ovarian cancer cells. Cancer Sci. 2018;109:2734-2745 pubmed publisher
	Arsène S, Ameta S, Lehman N, Griffiths A, Nghe P. Coupled catabolism and anabolism in autocatalytic RNA sets. Nucleic Acids Res. 2018;46:9660-9666 pubmed publisher
	Maclean A, Kimonis V, Balk J. Pathogenic mutations in NUBPL affect complex I activity and cold tolerance in the yeast model Yarrowia lipolytica. Hum Mol Genet. 2018;27:3697-3709 pubmed publisher
	Busto J, Elting A, Haase D, Spira F, Kuhlman J, Schäfer Herte M, et al. Lateral plasma membrane compartmentalization links protein function and turnover. EMBO J. 2018;37: pubmed publisher
	Wu L, Zhang X, Zhao L. Human ApoE Isoforms Differentially Modulate Brain Glucose and Ketone Body Metabolism: Implications for Alzheimer's Disease Risk Reduction and Early Intervention. J Neurosci. 2018;38:6665-6681 pubmed publisher
	Rodríguez Pulido M, Sánchez Aparicio M, Martinez Salas E, Garcia Sastre A, Sobrino F, Saiz M. Innate immune sensor LGP2 is cleaved by the Leader protease of foot-and-mouth disease virus. PLoS Pathog. 2018;14:e1007135 pubmed publisher
	Lai J, Bartlett E. Masking Differentially Affects Envelope-following Responses in Young and Aged Animals. Neuroscience. 2018;386:150-165 pubmed publisher
	Cutler S, Idris J, Ahmed A, Elelu N. Ornithodoros savignyi, the Tick Vector of "Candidatus Borrelia kalaharica" in Nigeria. J Clin Microbiol. 2018;56: pubmed publisher
	Steenbeek S, Pham T, de Ligt J, Zomer A, Knol J, Piersma S, et al. Cancer cells copy migratory behavior and exchange signaling networks via extracellular vesicles. EMBO J. 2018;37: pubmed publisher
	Zheng W, Yang X, Hu R, Cai R, Hofmann L, Wang Z, et al. Hydrophobic pore gates regulate ion permeation in polycystic kidney disease 2 and 2L1 channels. Nat Commun. 2018;9:2302 pubmed publisher
	Seitz S, Clarke P, Tyler K. Pharmacologic Depletion of Microglia Increases Viral Load in the Brain and Enhances Mortality in Murine Models of Flavivirus-Induced Encephalitis. J Virol. 2018;92: pubmed publisher
	Friggeri L, Hargrove T, Wawrzak Z, Blobaum A, Rachakonda G, Lindsley C, et al. Sterol 14?-Demethylase Structure-Based Design of VNI (( R)- N-(1-(2,4-Dichlorophenyl)-2-(1 H-imidazol-1-yl)ethyl)-4-(5-phenyl-1,3,4-oxadiazol-2-yl)benzamide)) Derivatives To Target Fungal Infections: Synthesis, Biological Evaluation, and Crystallogra. J Med Chem. 2018;61:5679-5691 pubmed publisher
	Bernal Bernal D, Abellón Ruiz J, Iniesta A, Pajares Martínez E, Bastida Martínez E, Fontes M, et al. Multifactorial control of the expression of a CRISPR-Cas system by an extracytoplasmic function σ/anti-σ pair and a global regulatory complex. Nucleic Acids Res. 2018;46:6726-6745 pubmed publisher
	Tosar J, Gámbaro F, Darré L, Pantano S, Westhof E, Cayota A. Dimerization confers increased stability to nucleases in 5' halves from glycine and glutamic acid tRNAs. Nucleic Acids Res. 2018;46:9081-9093 pubmed publisher
	Mishra R, Yadav R, Jones C, Nocadello S, Minasov G, Shuvalova L, et al. Structural and immunological characterization of E. coli derived recombinant CRM197 protein used as carrier in conjugate vaccines. Biosci Rep. 2018;38: pubmed publisher
	Goncalves C, Mulkey D. Bicarbonate directly modulates activity of chemosensitive neurons in the retrotrapezoid nucleus. J Physiol. 2018;596:4033-4042 pubmed publisher
	Patras K, Derieux J, Al Bassam M, Adiletta N, Vrbanac A, Lapek J, et al. Group B Streptococcus Biofilm Regulatory Protein A Contributes to Bacterial Physiology and Innate Immune Resistance. J Infect Dis. 2018;218:1641-1652 pubmed publisher
	Gurevich D, Severn C, Twomey C, Greenhough A, Cash J, Toye A, et al. Live imaging of wound angiogenesis reveals macrophage orchestrated vessel sprouting and regression. EMBO J. 2018;37: pubmed publisher
	Fong L, Yang M, Dos Santos Chaves R, Reyna S, Langness V, Woodruff G, et al. Full-length amyloid precursor protein regulates lipoprotein metabolism and amyloid-β clearance in human astrocytes. J Biol Chem. 2018;293:11341-11357 pubmed publisher
	Razidlo G, Burton K, McNiven M. Interleukin-6 promotes pancreatic cancer cell migration by rapidly activating the small GTPase CDC42. J Biol Chem. 2018;293:11143-11153 pubmed publisher
	Faralla C, Bastounis E, Ortega F, Light S, Rizzuto G, Gao L, et al. Listeria monocytogenes InlP interacts with afadin and facilitates basement membrane crossing. PLoS Pathog. 2018;14:e1007094 pubmed publisher
	Ferrara S, Bourdette D, Scanlan T. Hypothalamic-Pituitary-Thyroid Axis Perturbations in Male Mice by CNS-Penetrating Thyromimetics. Endocrinology. 2018;159:2733-2740 pubmed publisher
	Li Z, Li Y, Tang M, Peng B, Lu X, Yang Q, et al. Destabilization of linker histone H1.2 is essential for ATM activation and DNA damage repair. Cell Res. 2018;28:756-770 pubmed publisher
	Rossow L, Veitl S, Vorlova S, Wax J, Kuhn A, Maltzahn V, et al. LOX-catalyzed collagen stabilization is a proximal cause for intrinsic resistance to chemotherapy. Oncogene. 2018;37:4921-4940 pubmed publisher
	Krukowski K, Feng X, Paladini M, Chou A, Sacramento K, Grue K, et al. Temporary microglia-depletion after cosmic radiation modifies phagocytic activity and prevents cognitive deficits. Sci Rep. 2018;8:7857 pubmed publisher
	Yang T, Sun Y, Mao L, Zhang M, Li Q, Zhang L, et al. Brain ischemic preconditioning protects against ischemic injury and preserves the blood-brain barrier via oxidative signaling and Nrf2 activation. Redox Biol. 2018;17:323-337 pubmed publisher
	Zingue S, Njuh A, Tueche A, Tamsa J, Tchoupang E, Kakene S, et al. In Vitro Cytotoxicity and In Vivo Antimammary Tumor Effects of the Hydroethanolic Extract of Acacia seyal (Mimosaceae) Stem Bark. Biomed Res Int. 2018;2018:2024602 pubmed publisher
	Liu Y, Li Y, Liu S, Adeegbe D, Christensen C, Quinn M, et al. NK Cells Mediate Synergistic Antitumor Effects of Combined Inhibition of HDAC6 and BET in a SCLC Preclinical Model. Cancer Res. 2018;78:3709-3717 pubmed publisher
	Ottaviani S, Stebbing J, Frampton A, Zagorac S, Krell J, de Giorgio A, et al. TGF-β induces miR-100 and miR-125b but blocks let-7a through LIN28B controlling PDAC progression. Nat Commun. 2018;9:1845 pubmed publisher
	Thutupalli S, Geyer D, Singh R, Adhikari R, Stone H. Flow-induced phase separation of active particles is controlled by boundary conditions. Proc Natl Acad Sci U S A. 2018;115:5403-5408 pubmed publisher
	Wang Z, Gong K, Liu X, Zhang Z, Sun X, Wei Z, et al. C/EBPβ regulates delta-secretase expression and mediates pathogenesis in mouse models of Alzheimer's disease. Nat Commun. 2018;9:1784 pubmed publisher
	Schulze M, Hutterer M, Sabo A, Hoja S, Lorenz J, Rothhammer Hampl T, et al. Chronophin regulates active vitamin B6 levels and transcriptomic features of glioblastoma cell lines cultured under non-adherent, serum-free conditions. BMC Cancer. 2018;18:524 pubmed publisher
	Wren M, Lashley T, Arstad E, Sander K. Large inter- and intra-case variability of first generation tau PET ligand binding in neurodegenerative dementias. Acta Neuropathol Commun. 2018;6:34 pubmed publisher
	Klug J, Engelhardt M, Cadman C, Li H, Smith J, Ayala S, et al. Differential inputs to striatal cholinergic and parvalbumin interneurons imply functional distinctions. elife. 2018;7: pubmed publisher
	Clark K, Franco J, Schwizer S, Pang Z, Hawara E, Liebrand T, et al. An effector from the Huanglongbing-associated pathogen targets citrus proteases. Nat Commun. 2018;9:1718 pubmed publisher
	May Zhang L, Yermalitsky V, Huang J, Pleasent T, Borja M, Oda M, et al. Modification by isolevuglandins, highly reactive γ-ketoaldehydes, deleteriously alters high-density lipoprotein structure and function. J Biol Chem. 2018;293:9176-9187 pubmed publisher
	Liu W, Wang S, Zhou J, Pang X, Wang L. RNAi-mediated knockdown of MTNR1B without disrupting the effects of melatonin on apoptosis and cell cycle in bovine granulose cells. Peerj. 2018;6:e4463 pubmed publisher
	Sharma A, Zhang Y, Buikema J, Serpooshan V, Chirikian O, Kosaric N, et al. Stage-specific Effects of Bioactive Lipids on Human iPSC Cardiac Differentiation and Cardiomyocyte Proliferation. Sci Rep. 2018;8:6618 pubmed publisher
	Yang J, Leblanc F, Dighe S, Hamele C, Olson T, Feith D, et al. TRAIL mediates and sustains constitutive NF-?B activation in LGL leukemia. Blood. 2018;: pubmed publisher
	Yeom J, Gao X, Groisman E. Reduction in adaptor amounts establishes degradation hierarchy among protease substrates. Proc Natl Acad Sci U S A. 2018;115:E4483-E4492 pubmed publisher
	Kim C, Gao R, Sei E, Brandt R, Hartman J, Hatschek T, et al. Chemoresistance Evolution in Triple-Negative Breast Cancer Delineated by Single-Cell Sequencing. Cell. 2018;173:879-893.e13 pubmed publisher
	Petti L, Marlatt S, Luo Y, Scheideman E, Shelar A, DiMaio D. Regulation of C-C chemokine receptor 5 (CCR5) stability by Lys197 and by transmembrane protein aptamers that target it for lysosomal degradation. J Biol Chem. 2018;293:8787-8801 pubmed publisher
	Rodríguez Muela N, Parkhitko A, Grass T, Gibbs R, Norabuena E, Perrimon N, et al. Blocking p62-dependent SMN degradation ameliorates spinal muscular atrophy disease phenotypes. J Clin Invest. 2018;128:3008-3023 pubmed publisher
	Ma J, Fan Y, Zhang J, Feng S, Hu Z, Qiu W, et al. Testosterone-Dependent miR-26a-5p and let-7g-5p Act as Signaling Mediators to Regulate Sperm Apoptosis via Targeting PTEN and PMAIP1. Int J Mol Sci. 2018;19: pubmed publisher
	Zheng W, Zhou J, Luan Y, Yang J, Ge Y, Wang M, et al. Spatiotemporal Control of GPR37 Signaling and Its Behavioral Effects by Optogenetics. Front Mol Neurosci. 2018;11:95 pubmed publisher
	Ning J, Zhong Z, Fischer D, Harris G, Watkins S, Ambrose Z, et al. Truncated CPSF6 Forms Higher-Order Complexes That Bind and Disrupt HIV-1 Capsid. J Virol. 2018;92: pubmed publisher
	Park S, Kim K, Kwun M, Lee J, Won R, Han C, et al. Differential Regulation of NF-κB and Nrf2 by Bojungikki-Tang Is Associated with Suppressing Lung Inflammation. Evid Based Complement Alternat Med. 2018;2018:5059469 pubmed publisher
	Bobkov G, Gilbert N, Heun P. Centromere transcription allows CENP-A to transit from chromatin association to stable incorporation. J Cell Biol. 2018;217:1957-1972 pubmed publisher
	Chan C, Kiesel B, MONDRAGON A. Crystal Structure of Human Rpp20/Rpp25 Reveals Quaternary Level Adaptation of the Alba Scaffold as Structural Basis for Single-stranded RNA Binding. J Mol Biol. 2018;430:1403-1416 pubmed publisher
	Jelinek M, Balusikova K, Daniel P, Němcová Fürstová V, Kirubakaran P, Jacek M, et al. Substituents at the C3' and C3'N positions are critical for taxanes to overcome acquired resistance of cancer cells to paclitaxel. Toxicol Appl Pharmacol. 2018;347:79-91 pubmed publisher
	Sauvat A, Chen G, Müller K, Tong M, Aprahamian F, Durand S, et al. Trans-Fats Inhibit Autophagy Induced by Saturated Fatty Acids. EBioMedicine. 2018;30:261-272 pubmed publisher
	Simoni L, Delgado V, Ruer Laventie J, Bouis D, Soley A, Heyer V, et al. Trib1 Is Overexpressed in Systemic Lupus Erythematosus, While It Regulates Immunoglobulin Production in Murine B Cells. Front Immunol. 2018;9:373 pubmed publisher
	Webb M, Miller A, Howard T, Johnson B, Chumakov S, Fofanov Y, et al. Sequential gene regulatory events leading to glucocorticoid-evoked apoptosis of CEM human leukemic cells:interactions of MAPK, MYC and glucocorticoid pathways. Mol Cell Endocrinol. 2018;471:118-130 pubmed publisher
	Scheidel N, Kennedy J, Blacque O. Endosome maturation factors Rabenosyn-5/VPS45 and caveolin-1 regulate ciliary membrane and polycystin-2 homeostasis. EMBO J. 2018;37: pubmed publisher
	Zhang W, Shen J, Gu F, Zhang Y, Wu W, Weng J, et al. Monopolar spindle-one-binder protein 2 regulates the activity of large tumor suppressor/yes-associated protein to inhibit the motility of SMMC-7721 hepatocellular carcinoma cells. Oncol Lett. 2018;15:5375-5383 pubmed publisher
	Savitski M, Zinn N, Faelth Savitski M, Poeckel D, Gade S, Becher I, et al. Multiplexed Proteome Dynamics Profiling Reveals Mechanisms Controlling Protein Homeostasis. Cell. 2018;173:260-274.e25 pubmed publisher
	de Mingo Pulido Á, de Gregorio E, Chandra S, Colell A, Morales A, Kronenberg M, et al. Differential Role of Cathepsins S and B In Hepatic APC-Mediated NKT Cell Activation and Cytokine Secretion. Front Immunol. 2018;9:391 pubmed publisher
	Fassier C, Fréal A, Gasmi L, Delphin C, Ten Martin D, De Gois S, et al. Motor axon navigation relies on Fidgetin-like 1-driven microtubule plus end dynamics. J Cell Biol. 2018;217:1719-1738 pubmed publisher
	Lindsay P, Buell D, Scales D. The efficacy and safety of pre-hospital cooling after out-of-hospital cardiac arrest: a systematic review and meta-analysis. Crit Care. 2018;22:66 pubmed publisher
	Yu K, Davidson C, Wójtowicz A, Lisboa L, Wang T, Airo A, et al. LILRB1 polymorphisms influence posttransplant HCMV susceptibility and ligand interactions. J Clin Invest. 2018;128:1523-1537 pubmed publisher
	Kratzer I, Strazielle N, Saudrais E, MÃ¶nkkÃ¶nen K, Malleval C, Blondel S, et al. Glutathione Conjugation at the Blood-CSF Barrier Efficiently Prevents Exposure of the Developing Brain Fluid Environment to Blood-Borne Reactive Electrophilic Substances. J Neurosci. 2018;38:3466-3479 pubmed publisher
	Augustine V, Gökçe S, Lee S, Wang B, Davidson T, Reimann F, et al. Hierarchical neural architecture underlying thirst regulation. Nature. 2018;555:204-209 pubmed publisher
	González Rosa J, Sharpe M, Field D, Soonpaa M, Field L, BURNS C, et al. Myocardial Polyploidization Creates a Barrier to Heart Regeneration in Zebrafish. Dev Cell. 2018;44:433-446.e7 pubmed publisher
	Wattanapanitch M, Damkham N, Potirat P, Trakarnsanga K, Janan M, U Pratya Y, et al. One-step genetic correction of hemoglobin E/beta-thalassemia patient-derived iPSCs by the CRISPR/Cas9 system. Stem Cell Res Ther. 2018;9:46 pubmed publisher
	Oyarce K, Campos Mora M, Gajardo Carrasco T, Pino Lagos K. Vitamin C Fosters the In Vivo Differentiation of Peripheral CD4+ Foxp3- T Cells into CD4+ Foxp3+ Regulatory T Cells but Impairs Their Ability to Prolong Skin Allograft Survival. Front Immunol. 2018;9:112 pubmed publisher
	Sohn M, Korzeniowski M, Zewe J, Wills R, Hammond G, Humpolickova J, et al. PI(4,5)P2 controls plasma membrane PI4P and PS levels via ORP5/8 recruitment to ER-PM contact sites. J Cell Biol. 2018;217:1797-1813 pubmed publisher
	Hsu F, Spannl S, Ferguson C, Hyman A, Parton R, Zerial M. Rab5 and Alsin regulate stress-activated cytoprotective signaling on mitochondria. elife. 2018;7: pubmed publisher
	Kogut I, McCarthy S, Pavlova M, Astling D, Chen X, Jakimenko A, et al. High-efficiency RNA-based reprogramming of human primary fibroblasts. Nat Commun. 2018;9:745 pubmed publisher
	Kao Y, Chen P, Sun C, Chang Y, Lin Y, Tsai M, et al. Cyclic Mechanical Stretch Up-regulates Hepatoma-Derived Growth Factor Expression in Cultured Rat Aortic Smooth Muscle Cells. Biosci Rep. 2018;: pubmed publisher
	Collin G, Huna A, Warnier M, Flaman J, Bernard D. Transcriptional repression of DNA repair genes is a hallmark and a cause of cellular senescence. Cell Death Dis. 2018;9:259 pubmed publisher
	Warnier M, Flaman J, Chouabe C, Wiel C, Gras B, Griveau A, et al. The SCN9A channel and plasma membrane depolarization promote cellular senescence through Rb pathway. Aging Cell. 2018;17:e12736 pubmed publisher
	Panganiban C, Barth J, Darbelli L, Xing Y, Zhang J, Li H, et al. Noise-Induced Dysregulation of Quaking RNA Binding Proteins Contributes to Auditory Nerve Demyelination and Hearing Loss. J Neurosci. 2018;38:2551-2568 pubmed publisher
	Dirckx N, Tower R, Mercken E, Vangoitsenhoven R, Moreau Triby C, Breugelmans T, et al. Vhl deletion in osteoblasts boosts cellular glycolysis and improves global glucose metabolism. J Clin Invest. 2018;128:1087-1105 pubmed publisher
	Morais S, Figueiredo B, Assis N, Alvarenga D, de Magalhães M, Ferreira R, et al. Schistosoma mansoni SmKI-1 serine protease inhibitor binds to elastase and impairs neutrophil function and inflammation. PLoS Pathog. 2018;14:e1006870 pubmed publisher
	Thomasy S, Raghunathan V, Miyagi H, Evashenk A, Sermeno J, Tripp G, et al. Latrunculin B and substratum stiffness regulate corneal fibroblast to myofibroblast transformation. Exp Eye Res. 2018;170:101-107 pubmed publisher
	Li X, Jiang L. Multiple molecular mechanisms form a positive feedback loop driving amyloid β42 peptide-induced neurotoxicity via activation of the TRPM2 channel in hippocampal neurons. Cell Death Dis. 2018;9:195 pubmed publisher
	Dillenburg A, Ireland G, Holloway R, Davies C, Evans F, Swire M, et al. Activin receptors regulate the oligodendrocyte lineage in health and disease. Acta Neuropathol. 2018;135:887-906 pubmed publisher
	Morellet N, Li X, Wieninger S, Taylor J, Bischerour J, Moriau S, et al. Sequence-specific DNA binding activity of the cross-brace zinc finger motif of the piggyBac transposase. Nucleic Acids Res. 2018;46:2660-2677 pubmed publisher
	McIntyre W, Netzband R, Bonenfant G, Biegel J, Miller C, Fuchs G, et al. Positive-sense RNA viruses reveal the complexity and dynamics of the cellular and viral epitranscriptomes during infection. Nucleic Acids Res. 2018;46:5776-5791 pubmed publisher
	Mishra J, More A, Kumar S. Elevated androgen levels induce hyperinsulinemia through increase in Ins1 transcription in pancreatic beta cells in female rats. Biol Reprod. 2018;98:520-531 pubmed publisher
	Wang H, Yuan Q, Niu M, Zhang W, Wen L, Fu H, et al. Transcriptional regulation of P63 on the apoptosis of male germ cells and three stages of spermatogenesis in mice. Cell Death Dis. 2018;9:76 pubmed publisher
	Goins C, Dajnowicz S, Smith M, Parks J, Ronning D. Mycolyltransferase from Mycobacterium tuberculosis in covalent complex with tetrahydrolipstatin provides insights into antigen 85 catalysis. J Biol Chem. 2018;293:3651-3662 pubmed publisher
	Poirel O, Mella S, Videau C, Ramet L, Davoli M, Herzog E, et al. Moderate decline in select synaptic markers in the prefrontal cortex (BA9) of patients with Alzheimer's disease at various cognitive stages. Sci Rep. 2018;8:938 pubmed publisher
	Carroll B, Otten E, Manni D, Stefanatos R, Menzies F, Smith G, et al. Oxidation of SQSTM1/p62 mediates the link between redox state and protein homeostasis. Nat Commun. 2018;9:256 pubmed publisher
	Kanellopoulos A, Koenig J, Huang H, Pyrski M, Millet Q, Lolignier S, et al. Mapping protein interactions of sodium channel NaV1.7 using epitope-tagged gene-targeted mice. EMBO J. 2018;37:427-445 pubmed publisher
	Freeman S, Vega A, Riedl M, Collins R, Ostrowski P, Woods E, et al. Transmembrane Pickets Connect Cyto- and Pericellular Skeletons Forming Barriers to Receptor Engagement. Cell. 2018;172:305-317.e10 pubmed publisher
	Faraz M, Herdenberg C, Holmlund C, Henriksson R, Hedman H. A protein interaction network centered on leucine-rich repeats and immunoglobulin-like domains 1 (LRIG1) regulates growth factor receptors. J Biol Chem. 2018;293:3421-3435 pubmed publisher
	Jones K, Versteeg L, Damania A, Keegan B, Kendricks A, Pollet J, et al. Vaccine-Linked Chemotherapy Improves Benznidazole Efficacy for Acute Chagas Disease. Infect Immun. 2018;86: pubmed publisher
	Barragán Iglesias P, Lou T, Bhat V, Megat S, Burton M, Price T, et al. Inhibition of Poly(A)-binding protein with a synthetic RNA mimic reduces pain sensitization in mice. Nat Commun. 2018;9:10 pubmed publisher
	Bhome R, Goh R, Bullock M, Pillar N, Thirdborough S, Mellone M, et al. Exosomal microRNAs derived from colorectal cancer-associated fibroblasts: role in driving cancer progression. Aging (Albany NY). 2017;9:2666-2694 pubmed publisher
	Hamilton C, Abney K, Vasauskas A, Alexeyev M, Li N, Honkanen R, et al. Serine/threonine phosphatase 5 (PP5C/PPP5C) regulates the ISOC channel through a PP5C-FKBP51 axis. Pulm Circ. 2018;8:2045893217753156 pubmed publisher
	Falcon B, Noad J, McMahon H, Randow F, Goedert M. Galectin-8-mediated selective autophagy protects against seeded tau aggregation. J Biol Chem. 2018;293:2438-2451 pubmed publisher
	Wu D, Lee S, Luo J, Xia H, Gushchina S, Richardson P, et al. Intraneural Injection of ATP Stimulates Regeneration of Primary Sensory Axons in the Spinal Cord. J Neurosci. 2018;38:1351-1365 pubmed publisher
	Wu C, Zheng A, Jiang L, Rowse M, Stanevich V, Chen H, et al. Methylation-regulated decommissioning of multimeric PP2A complexes. Nat Commun. 2017;8:2272 pubmed publisher
	Blyth J, Makrantoni V, Barton R, Spanos C, Rappsilber J, Marston A. Genes Important for Schizosaccharomyces pombe Meiosis Identified Through a Functional Genomics Screen. Genetics. 2018;208:589-603 pubmed publisher
	Yui S, Azzolin L, Maimets M, Pedersen M, Fordham R, Hansen S, et al. YAP/TAZ-Dependent Reprogramming of Colonic Epithelium Links ECM Remodeling to Tissue Regeneration. Cell Stem Cell. 2018;22:35-49.e7 pubmed publisher
	Rollie C, Graham S, Rouillon C, White M. Prespacer processing and specific integration in a Type I-A CRISPR system. Nucleic Acids Res. 2017;: pubmed publisher
	Welty S, Teng Y, Liang Z, Zhao W, Sanders L, Greenamyre J, et al. RAD52 is required for RNA-templated recombination repair in post-mitotic neurons. J Biol Chem. 2018;293:1353-1362 pubmed publisher
	Huynh T, Liao F, Francis C, Robinson G, Serrano J, Jiang H, et al. Age-Dependent Effects of apoE Reduction Using Antisense Oligonucleotides in a Model of β-amyloidosis. Neuron. 2017;96:1013-1023.e4 pubmed publisher
	Maltby S, Lochrin A, Bartlett B, Tay H, Weaver J, Poulton I, et al. Osteoblasts Are Rapidly Ablated by Virus-Induced Systemic Inflammation following Lymphocytic Choriomeningitis Virus or Pneumonia Virus of Mice Infection in Mice. J Immunol. 2018;200:632-642 pubmed publisher
	Shen N, Ng S, Toepp S, Ljubicic V. Protein arginine methyltransferase expression and activity during myogenesis. Biosci Rep. 2018;38: pubmed publisher
	Prokhorova I, Altman R, Djumagulov M, Shrestha J, Urzhumtsev A, Ferguson A, et al. Aminoglycoside interactions and impacts on the eukaryotic ribosome. Proc Natl Acad Sci U S A. 2017;114:E10899-E10908 pubmed publisher
	Johnson N, Condello C, Guan S, Oehler A, Becker J, Gavidia M, et al. Evidence for sortilin modulating regional accumulation of human tau prions in transgenic mice. Proc Natl Acad Sci U S A. 2017;114:E11029-E11036 pubmed publisher
	Figueroa I, Barnum T, Somasekhar P, Carlström C, Engelbrektson A, Coates J. Metagenomics-guided analysis of microbial chemolithoautotrophic phosphite oxidation yields evidence of a seventh natural CO2 fixation pathway. Proc Natl Acad Sci U S A. 2018;115:E92-E101 pubmed publisher
	O Donnell J, Byrnes L, Cooley R, Sondermann H. A hereditary spastic paraplegia-associated atlastin variant exhibits defective allosteric coupling in the catalytic core. J Biol Chem. 2018;293:687-700 pubmed publisher
	Liu Z, Bryant N, Kumaran R, Beilina A, Abeliovich A, Cookson M, et al. LRRK2 phosphorylates membrane-bound Rabs and is activated by GTP-bound Rab7L1 to promote recruitment to the trans-Golgi network. Hum Mol Genet. 2017;: pubmed publisher
	Alvarez S, Sviderskiy V, Terzi E, Papagiannakopoulos T, Moreira A, Adams S, et al. NFS1 undergoes positive selection in lung tumours and protects cells from ferroptosis. Nature. 2017;551:639-643 pubmed publisher
	Milenkovic I, Stojanovic T, Aronica E, Fülöp L, Bozso Z, Mate Z, et al. GABAA receptor subunit deregulation in the hippocampus of human foetuses with Down syndrome. Brain Struct Funct. 2018;223:1501-1518 pubmed publisher
	Duong T, Ravisankar P, Song Y, Gafranek J, Rydeen A, Dohn T, et al. Nr2f1a balances atrial chamber and atrioventricular canal size via BMP signaling-independent and -dependent mechanisms. Dev Biol. 2018;434:7-14 pubmed publisher
	Wang L, Collings C, Zhao Z, Cozzolino K, Ma Q, Liang K, et al. A cytoplasmic COMPASS is necessary for cell survival and triple-negative breast cancer pathogenesis by regulating metabolism. Genes Dev. 2017;31:2056-2066 pubmed publisher
	Genna A, Lapetina S, Lukic N, Twafra S, Meirson T, Sharma V, et al. Pyk2 and FAK differentially regulate invadopodia formation and function in breast cancer cells. J Cell Biol. 2018;217:375-395 pubmed publisher
	An M, Li S, Yao H, Li C, Wang J, Sun J, et al. BAG3 directly stabilizes Hexokinase 2 mRNA and promotes aerobic glycolysis in pancreatic cancer cells. J Cell Biol. 2017;216:4091-4105 pubmed publisher
	Fuster C, Perrot J, Berthier C, Jacquemond V, Charnet P, Allard B. Na leak with gating pore properties in hypokalemic periodic paralysis V876E mutant muscle Ca channel. J Gen Physiol. 2017;149:1139-1148 pubmed publisher
	Lê V, Riteau B, Alessi M, Couture C, Jandrot Perrus M, Rhéaume C, et al. Protease-activated receptor 1 inhibition protects mice against thrombin-dependent respiratory syncytial virus and human metapneumovirus infections. Br J Pharmacol. 2017;: pubmed publisher
	Ainola M, Porola P, Takakubo Y, Przybyla B, Kouri V, Tolvanen T, et al. Activation of plasmacytoid dendritic cells by apoptotic particles - mechanism for the loss of immunologic tolerance in Sjögren's syndrome. Clin Exp Immunol. 2017;: pubmed publisher
	Yeh H, Lee S, Chang C, Hu C, Jou Y. Pyrimidine metabolic rate limiting enzymes in poorly-differentiated hepatocellular carcinoma are signature genes of cancer stemness and associated with poor prognosis. Oncotarget. 2017;8:77734-77751 pubmed publisher
	Pierce R, Merola J, Lavik J, Kluger M, Huttner A, Khokha M, et al. A p190BRhoGAP mutation and prolonged RhoB activation in fatal systemic capillary leak syndrome. J Exp Med. 2017;214:3497-3505 pubmed publisher
	Kutchukian C, Szentesi P, Allard B, Trochet D, Beuvin M, Berthier C, et al. Impaired excitation-contraction coupling in muscle fibres from the dynamin2R465W mouse model of centronuclear myopathy. J Physiol. 2017;595:7369-7382 pubmed publisher
	Obajemu A, Rao N, Dilley K, Vargas J, Sheikh F, Donnelly R, et al. IFN-Î»4 Attenuates Antiviral Responses by Enhancing Negative Regulation of IFN Signaling. J Immunol. 2017;199:3808-3820 pubmed publisher
	Tosh J, Rickman M, Rhymes E, Norona F, Clayton E, Mucke L, et al. The integration site of the APP transgene in the J20 mouse model of Alzheimer's disease. Wellcome Open Res. 2017;2:84 pubmed publisher
	Gallagher M, Posavi M, Huang P, Unger T, Berlyand Y, Gruenewald A, et al. A Dementia-Associated Risk Variant near TMEM106B Alters Chromatin Architecture and Gene Expression. Am J Hum Genet. 2017;101:643-663 pubmed publisher
	Rodriguez Rodriguez P, Sandebring Matton A, Merino Serrais P, Parrado Fernandez C, Rabano A, Winblad B, et al. Tau hyperphosphorylation induces oligomeric insulin accumulation and insulin resistance in neurons. Brain. 2017;: pubmed publisher
	Nakajima E, Hammond K, Hirata M, Shearer T, Azuma M. Contribution of Calpain and Caspases to Cell Death in Cultured Monkey RPE Cells. Invest Ophthalmol Vis Sci. 2017;58:5412-5420 pubmed publisher
	Lathuilière A, Valdés P, Papin S, Cacquevel M, Maclachlan C, Knott G, et al. Motifs in the tau protein that control binding to microtubules and aggregation determine pathological effects. Sci Rep. 2017;7:13556 pubmed publisher
	Huggins I, Bos T, Gaylord O, Jessen C, Lonquich B, Puranen A, et al. The WNT target SP5 negatively regulates WNT transcriptional programs in human pluripotent stem cells. Nat Commun. 2017;8:1034 pubmed publisher
	Zhang S, Eitan E, Wu T, Mattson M. Intercellular transfer of pathogenic α-synuclein by extracellular vesicles is induced by the lipid peroxidation product 4-hydroxynonenal. Neurobiol Aging. 2018;61:52-65 pubmed publisher
	Anderson S, Mueller B, Lange E, Senes A. Combination of C?-H Hydrogen Bonds and van der Waals Packing Modulates the Stability of GxxxG-Mediated Dimers in Membranes. J Am Chem Soc. 2017;139:15774-15783 pubmed publisher
	Pratt Riccio L, De Souza Perce Da Silva D, Da Costa Lima Junior J, Pratt Riccio E, Ribeiro Alves M, Santos F, et al. Synthetic Antigens Derived from Plasmodium falciparum Sporozoite, Liver, and Blood Stages: Naturally Acquired Immune Response and Human Leukocyte Antigen Associations in Individuals Living in a Brazilian Endemic Area. Am J Trop Med Hyg. 2017;97:1581-1592 pubmed publisher
	Xiao Y, Xie Y, Xu M, Liu S, Jiang C, Zhao F, et al. Development and Evaluation of a Loop-Mediated Isothermal Amplification Assay for the Detection of Treponema pallidum DNA in the Peripheral Blood of Secondary Syphilis Patients. Am J Trop Med Hyg. 2017;: pubmed publisher
	Duncan F, Jasti S, Paulson A, Kelsh J, Fegley B, Gerton J. Age-associated dysregulation of protein metabolism in the mammalian oocyte. Aging Cell. 2017;16:1381-1393 pubmed publisher
	Kniewel R, Murakami H, Liu Y, Ito M, Ohta K, Hollingsworth N, et al. Histone H3 Threonine 11 Phosphorylation Is Catalyzed Directly by the Meiosis-Specific Kinase Mek1 and Provides a Molecular Readout of Mek1 Activity in Vivo. Genetics. 2017;207:1313-1333 pubmed publisher
	Nair J, Attarwala H, Sehgal A, Wang Q, Aluri K, Zhang X, et al. Impact of enhanced metabolic stability on pharmacokinetics and pharmacodynamics of GalNAc-siRNA conjugates. Nucleic Acids Res. 2017;45:10969-10977 pubmed publisher
	Smith Z, Shi J, Gu H, Donaghey J, Clement K, Cacchiarelli D, et al. Epigenetic restriction of extraembryonic lineages mirrors the somatic transition to cancer. Nature. 2017;549:543-547 pubmed publisher
	Yeow I, Howard G, Chadwick J, Mendoza Topaz C, Hansen C, Nichols B, et al. EHD Proteins Cooperate to Generate Caveolar Clusters and to Maintain Caveolae during Repeated Mechanical Stress. Curr Biol. 2017;27:2951-2962.e5 pubmed publisher
	Buxboim A, Irianto J, Swift J, Athirasala A, Shin J, Rehfeldt F, et al. Coordinated increase of nuclear tension and lamin-A with matrix stiffness outcompetes lamin-B receptor that favors soft tissue phenotypes. Mol Biol Cell. 2017;28:3333-3348 pubmed publisher
	Li P, Wuthrick E, Rappaport J, Kraft C, Lin J, Marszalowicz G, et al. GUCY2C Signaling Opposes the Acute Radiation-Induced GI Syndrome. Cancer Res. 2017;77:5095-5106 pubmed publisher
	Zhang Y, Kurupati R, Liu L, Zhou X, Zhang G, Hudaihed A, et al. Enhancing CD8+ T Cell Fatty Acid Catabolism within a Metabolically Challenging Tumor Microenvironment Increases the Efficacy of Melanoma Immunotherapy. Cancer Cell. 2017;32:377-391.e9 pubmed publisher
	Bosse K, Raman P, Zhu Z, Lane M, Martinez D, Heitzeneder S, et al. Identification of GPC2 as an Oncoprotein and Candidate Immunotherapeutic Target in High-Risk Neuroblastoma. Cancer Cell. 2017;32:295-309.e12 pubmed publisher
	Kwon H, Chen H, Mathis D, Benoist C. Different molecular complexes that mediate transcriptional induction and repression by FoxP3. Nat Immunol. 2017;18:1238-1248 pubmed publisher
	Jewett C, Vanderleest T, Miao H, Xie Y, Madhu R, Loerke D, et al. Planar polarized Rab35 functions as an oscillatory ratchet during cell intercalation in the Drosophila epithelium. Nat Commun. 2017;8:476 pubmed publisher
	Fuster C, Perrot J, Berthier C, Jacquemond V, Allard B. Elevated resting H+ current in the R1239H type 1 hypokalaemic periodic paralysis mutated Ca2+ channel. J Physiol. 2017;595:6417-6428 pubmed publisher
	Salerno F, Paolini N, Stark R, von Lindern M, Wolkers M. Distinct PKC-mediated posttranscriptional events set cytokine production kinetics in CD8+ T cells. Proc Natl Acad Sci U S A. 2017;114:9677-9682 pubmed publisher
	Gainullin M, Zhukov I, Zhou X, Mo Y, Astakhova L, Ernberg I, et al. Degradation of cofilin is regulated by Cbl, AIP4 and Syk resulting in increased migration of LMP2A positive nasopharyngeal carcinoma cells. Sci Rep. 2017;7:9012 pubmed publisher
	Khan A, Simms V, Pike J, Thomas S, Morgan N. CRISPR-Cas9 Mediated Labelling Allows for Single Molecule Imaging and Resolution. Sci Rep. 2017;7:8450 pubmed publisher
	Kaspar J, Underhill S, Shields R, Reyes A, Rosenzweig S, Hagen S, et al. Intercellular Communication via the comX-Inducing Peptide (XIP) of Streptococcus mutans. J Bacteriol. 2017;199: pubmed publisher
	Redeker J, Schmitt B, Grigull N, Braun C, Büttner A, Jansson V, et al. Effect of electromagnetic fields on human osteoarthritic and non-osteoarthritic chondrocytes. BMC Complement Altern Med. 2017;17:402 pubmed publisher
	Zhang Y, Sun J, Li F, Grogan T, Vergara J, Luan Q, et al. Salivary extracellular RNA biomarkers for insulin resistance detection in hispanics. Diabetes Res Clin Pract. 2017;132:85-94 pubmed publisher
	Kim S, D Acunto V, Kokona B, Hofmann J, Cunningham N, Bistline E, et al. Sedimentation Velocity Analysis with Fluorescence Detection of Mutant Huntingtin Exon 1 Aggregation in Drosophila melanogaster and Caenorhabditis elegans. Biochemistry. 2017;56:4676-4688 pubmed publisher
	Zhang P, Li K, Yang G, Xia C, Polston J, Li G, et al. Cytotoxic protein from the mushroom Coprinus comatus possesses a unique mode for glycan binding and specificity. Proc Natl Acad Sci U S A. 2017;114:8980-8985 pubmed publisher
	Wälti M, Schmidt T, Murray D, Wang H, Hinshaw J, Clore G. Chaperonin GroEL accelerates protofibril formation and decorates fibrils of the Het-s prion protein. Proc Natl Acad Sci U S A. 2017;114:9104-9109 pubmed publisher
	Xu X, Song N, Zhang X, Jiao X, Hu J, Liang M, et al. Renal Protection Mediated by Hypoxia Inducible Factor-1Î± Depends on Proangiogenesis Function of miR-21 by Targeting Thrombospondin 1. Transplantation. 2017;101:1811-1819 pubmed publisher
	Luna J, Barajas J, Teng K, Sun H, Moore M, Rice C, et al. Argonaute CLIP Defines a Deregulated miR-122-Bound Transcriptome that Correlates with Patient Survival in Human Liver Cancer. Mol Cell. 2017;67:400-410.e7 pubmed publisher
	Bennett M, Abdad M, Stenos J. Serological Evidence of Rickettsia spp. in Western Australian Dogs. Am J Trop Med Hyg. 2017;97:407-412 pubmed publisher
	Kim E, Sakata K, Liao F. Bidirectional interplay of HSF1 degradation and UPR activation promotes tau hyperphosphorylation. PLoS Genet. 2017;13:e1006849 pubmed publisher
	Fitzpatrick A, Falcon B, He S, Murzin A, Murshudov G, Garringer H, et al. Cryo-EM structures of tau filaments from Alzheimer's disease. Nature. 2017;547:185-190 pubmed publisher
	Yadav P, Rajasekharan R. The m6A methyltransferase Ime4 epitranscriptionally regulates triacylglycerol metabolism and vacuolar morphology in haploid yeast cells. J Biol Chem. 2017;292:13727-13744 pubmed publisher
	Ornaghi S, Hsieh L, Bordey A, Vergani P, Paidas M, van den Pol A. Valnoctamide Inhibits Cytomegalovirus Infection in Developing Brain and Attenuates Neurobehavioral Dysfunctions and Brain Abnormalities. J Neurosci. 2017;37:6877-6893 pubmed publisher
	Goubert E, Mircheva Y, Lasorsa F, Melon C, Profilo E, Sutera J, et al. Inhibition of the Mitochondrial Glutamate Carrier SLC25A22 in Astrocytes Leads to Intracellular Glutamate Accumulation. Front Cell Neurosci. 2017;11:149 pubmed publisher
	Liu K, Hughes J, Hay S, Scrutton N. Liver microsomal lipid enhances the activity and redox coupling of colocalized cytochrome P450 reductase-cytochrome P450 3A4 in nanodiscs. FEBS J. 2017;284:2302-2319 pubmed publisher
	Lood C, Arve S, LEDBETTER J, Elkon K. TLR7/8 activation in neutrophils impairs immune complex phagocytosis through shedding of FcgRIIA. J Exp Med. 2017;214:2103-2119 pubmed publisher
	Liu F, Dawadi S, Maize K, Dai R, Park S, Schnappinger D, et al. Structure-Based Optimization of Pyridoxal 5'-Phosphate-Dependent Transaminase Enzyme (BioA) Inhibitors that Target Biotin Biosynthesis in Mycobacterium tuberculosis. J Med Chem. 2017;60:5507-5520 pubmed publisher
	Jones D, Uddin M, Gruninger R, Pham T, Thomas D, Boraston A, et al. Discovery and characterization of family 39 glycoside hydrolases from rumen anaerobic fungi with polyspecific activity on rare arabinosyl substrates. J Biol Chem. 2017;292:12606-12620 pubmed publisher
	Scott D, Hammill J, Min J, Rhee D, Connelly M, Sviderskiy V, et al. Blocking an N-terminal acetylation-dependent protein interaction inhibits an E3 ligase. Nat Chem Biol. 2017;13:850-857 pubmed publisher
	Fang Y, Zhang J, Xiao L, Ai X, Cao Y, Yang H. Phosphate Framework Electrode Materials for Sodium Ion Batteries. Adv Sci (Weinh). 2017;4:1600392 pubmed publisher
	Wang C, Pallan P, Zhang W, Lei L, Yoshimoto F, Waterman M, et al. Functional analysis of human cytochrome P450 21A2 variants involved in congenital adrenal hyperplasia. J Biol Chem. 2017;292:10767-10778 pubmed publisher
	Sangodkar J, Perl A, Tohme R, Kiselar J, Kastrinsky D, Zaware N, et al. Activation of tumor suppressor protein PP2A inhibits KRAS-driven tumor growth. J Clin Invest. 2017;127:2081-2090 pubmed publisher
	Li S, Sullivan N, Rouphael N, Yu T, Banton S, Maddur M, et al. Metabolic Phenotypes of Response to Vaccination in Humans. Cell. 2017;169:862-877.e17 pubmed publisher
	Kardoush M, Ward B, Ndao M. Serum Carbonic Anhydrase 1 is a Biomarker for Diagnosis of Human Schistosoma mansoni Infection. Am J Trop Med Hyg. 2017;96:842-849 pubmed publisher
	Ferrin M, Subramaniam A. Kinetic modeling predicts a stimulatory role for ribosome collisions at elongation stall sites in bacteria. elife. 2017;6: pubmed publisher
	Mishra J, More A, Hankins G, Kumar S. Hyperandrogenemia reduces endothelium-derived hyperpolarizing factor-mediated relaxation in mesenteric artery of female rats. Biol Reprod. 2017;96:1221-1230 pubmed publisher
	Coleman K, BÃ©kÃ©s M, Chapman J, Crist S, Jones M, Ueberheide B, et al. SENP8 limits aberrant neddylation of NEDD8 pathway components to promote cullin-RING ubiquitin ligase function. elife. 2017;6: pubmed publisher
	Valdivia A, Goicoechea S, Awadia S, Zinn A, Garcia Mata R. Regulation of circular dorsal ruffles, macropinocytosis, and cell migration by RhoG and its exchange factor, Trio. Mol Biol Cell. 2017;28:1768-1781 pubmed publisher
	Seth P, Csizmadia E, Hedblom A, Vuerich M, Xie H, Li M, et al. Deletion of Lactate Dehydrogenase-A in Myeloid Cells Triggers Antitumor Immunity. Cancer Res. 2017;77:3632-3643 pubmed publisher
	Wen X, Zhang X, Szewczyk G, El Hussein A, Huang Y, Sarna T, et al. Potassium Iodide Potentiates Antimicrobial Photodynamic Inactivation Mediated by Rose Bengal in In Vitro and In Vivo Studies. Antimicrob Agents Chemother. 2017;61: pubmed publisher
	Halliday M, Radford H, Zents K, Molloy C, Moreno J, Verity N, et al. Repurposed drugs targeting eIF2α-P-mediated translational repression prevent neurodegeneration in mice. Brain. 2017;140:1768-1783 pubmed publisher
	Haase E, Kou Y, Sabharwal A, Liao Y, Lan T, Lindqvist C, et al. Comparative genomics and evolution of the amylase-binding proteins of oral streptococci. BMC Microbiol. 2017;17:94 pubmed publisher
	Nandhu M, Kwiatkowska A, Bhaskaran V, Hayes J, Hu B, Viapiano M. Tumor-derived fibulin-3 activates pro-invasive NF-ÎºB signaling in glioblastoma cells and their microenvironment. Oncogene. 2017;36:4875-4886 pubmed publisher
	Chang K, Hertz J, Zhang X, Jin X, Shaw P, Derosa B, et al. Novel Regulatory Mechanisms for the SoxC Transcriptional Network Required for Visual Pathway Development. J Neurosci. 2017;37:4967-4981 pubmed publisher
	Skopova K, Tomalova B, Kanchev I, Rossmann P, Svedova M, Adkins I, et al. Cyclic AMP-Elevating Capacity of Adenylate Cyclase Toxin-Hemolysin Is Sufficient for Lung Infection but Not for Full Virulence of Bordetella pertussis. Infect Immun. 2017;85: pubmed publisher
	Ritter Makinson S, Paquet M, Bogenpohl J, Rodin R, Chris Yun C, Weinman E, et al. Group II metabotropic glutamate receptor interactions with NHERF scaffold proteins: Implications for receptor localization in brain. Neuroscience. 2017;353:58-75 pubmed publisher
	Singh A, Xu Y. Heme deficiency sensitizes yeast cells to oxidative stress induced by hydroxyurea. J Biol Chem. 2017;292:9088-9103 pubmed publisher
	Turner A, Ong C, Djoko K, West N, Davies M, McEwan A, et al. The PerR-Regulated P1B-4-Type ATPase (PmtA) Acts as a Ferrous Iron Efflux Pump in Streptococcus pyogenes. Infect Immun. 2017;85: pubmed publisher
	Harding C, Pulido M, Di Venanzio G, Kinsella R, Webb A, Scott N, et al. Pathogenic Acinetobacter species have a functional type I secretion system and contact-dependent inhibition systems. J Biol Chem. 2017;292:9075-9087 pubmed publisher
	Lee H, Wang H, Baladandayuthapani V, Lin H, He J, Jones R, et al. RNA Polymerase I Inhibition with CX-5461 as a Novel Therapeutic Strategy to Target MYC in Multiple Myeloma. Br J Haematol. 2017;177:80-94 pubmed publisher
	Cummings K, Belin S, Popescu G. Residues in the GluN1 C-terminal domain control kinetics and pharmacology of GluN1/GluN3A N-methyl-d-aspartate receptors. Neuropharmacology. 2017;119:40-47 pubmed publisher
	Manning A, Highland H, Gasser J, Sim X, Tukiainen T, Fontanillas P, et al. A Low-Frequency Inactivating AKT2 Variant Enriched in the Finnish Population Is Associated With Fasting Insulin Levels and Type 2 Diabetes Risk. Diabetes. 2017;66:2019-2032 pubmed publisher
	VALLABHAJOSYULA P, Korutla L, Habertheuer A, Yu M, Rostami S, Yuan C, et al. Tissue-specific exosome biomarkers for noninvasively monitoring immunologic rejection of transplanted tissue. J Clin Invest. 2017;127:1375-1391 pubmed publisher
	Poça K, Parente T, Chagas L, Leal B, Leal H, Paumgartten F, et al. Interstrain differences in the expression and activity of Cyp2a5 in the mouse liver. BMC Res Notes. 2017;10:125 pubmed publisher
	Chen J, Kuo C, Pai P, Ho T, Chen T, Tsai F, et al. Mitochondrial ROS-induced ERK1/2 activation and HSF2-mediated AT1 R upregulation are required for doxorubicin-induced cardiotoxicity. J Cell Physiol. 2018;233:463-475 pubmed publisher
	Meng X, Rose L, Han Y, Deng J, Xiang Y. Vaccinia Virus A6 Is a Two-Domain Protein Requiring a Cognate N-Terminal Domain for Full Viral Membrane Assembly Activity. J Virol. 2017;91: pubmed publisher
	Li L, Baxter S, Gu N, Ji M, Zhan X. Missing-in-metastasis protein downregulates CXCR4 by promoting ubiquitylation and interaction with small Rab GTPases. J Cell Sci. 2017;130:1475-1485 pubmed publisher
	Hargrove T, Friggeri L, Wawrzak Z, Qi A, Hoekstra W, Schotzinger R, et al. Structural analyses of Candida albicans sterol 14Î±-demethylase complexed with azole drugs address the molecular basis of azole-mediated inhibition of fungal sterol biosynthesis. J Biol Chem. 2017;292:6728-6743 pubmed publisher
	Oulhen N, Swartz S, Laird J, Mascaro A, Wessel G. Transient translational quiescence in primordial germ cells. Development. 2017;144:1201-1210 pubmed publisher
	Gache V, Gomes E, Cadot B. Microtubule motors involved in nuclear movement during skeletal muscle differentiation. Mol Biol Cell. 2017;28:865-874 pubmed publisher
	Zhou L, Liu J, Xiang M, Olson P, Guzzetta A, Zhang K, et al. Gata4 potentiates second heart field proliferation and Hedgehog signaling for cardiac septation. Proc Natl Acad Sci U S A. 2017;114:E1422-E1431 pubmed publisher
	Mueller L, Hauser P, Gauye F, Greub G. Lausannevirus Encodes a Functional Dihydrofolate Reductase Susceptible to Proguanil. Antimicrob Agents Chemother. 2017;61: pubmed publisher
	Hays S, Yan L, Silver P, Ducat D. Synthetic photosynthetic consortia define interactions leading to robustness and photoproduction. J Biol Eng. 2017;11:4 pubmed publisher
	Gong Y, Handa N, Kowalczykowski S, de Lange T. PHF11 promotes DSB resection, ATR signaling, and HR. Genes Dev. 2017;31:46-58 pubmed publisher
	Jay T, Hirsch A, Broihier M, Miller C, Neilson L, Ransohoff R, et al. Disease Progression-Dependent Effects of TREM2 Deficiency in a Mouse Model of Alzheimer's Disease. J Neurosci. 2017;37:637-647 pubmed publisher
	Toteva T, Mason B, Kanoh Y, BrÃ¸gger P, Green D, Verhein Hansen J, et al. Establishment of expression-state boundaries by Rif1 and Taz1 in fission yeast. Proc Natl Acad Sci U S A. 2017;114:1093-1098 pubmed publisher
	Wang P, Joberty G, Buist A, Vanoosthuyse A, Stancu I, Vasconcelos B, et al. Tau interactome mapping based identification of Otub1 as Tau deubiquitinase involved in accumulation of pathological Tau forms in vitro and in vivo. Acta Neuropathol. 2017;133:731-749 pubmed publisher
	Troegeler A, Mercier I, Cougoule C, Pietretti D, Colom A, Duval C, et al. C-type lectin receptor DCIR modulates immunity to tuberculosis by sustaining type I interferon signaling in dendritic cells. Proc Natl Acad Sci U S A. 2017;114:E540-E549 pubmed publisher
	Wang J, Sun Z, Gou W, Adams D, Cui W, Morgan K, et al. Î±-1 Antitrypsin Enhances Islet Engraftment by Suppression of Instant Blood-Mediated Inflammatory Reaction. Diabetes. 2017;66:970-980 pubmed publisher
	Monaghan C, Nechiporuk T, Jeng S, McWeeney S, Wang J, Rosenfeld M, et al. REST corepressors RCOR1 and RCOR2 and the repressor INSM1 regulate the proliferation-differentiation balance in the developing brain. Proc Natl Acad Sci U S A. 2017;114:E406-E415 pubmed publisher
	Rahman S, Zorca C, Traboulsi T, Noutahi E, Krause M, Mader S, et al. Single-cell profiling reveals that eRNA accumulation at enhancer-promoter loops is not required to sustain transcription. Nucleic Acids Res. 2017;45:3017-3030 pubmed publisher
	Panda A, Grammatikakis I, Kim K, De S, Martindale J, Munk R, et al. Identification of senescence-associated circular RNAs (SAC-RNAs) reveals senescence suppressor CircPVT1. Nucleic Acids Res. 2017;45:4021-4035 pubmed publisher
	Herrera Carrillo E, Gao Z, Harwig A, Heemskerk M, Berkhout B. The influence of the 5΄-terminal nucleotide on AgoshRNA activity and biogenesis: importance of the polymerase III transcription initiation site. Nucleic Acids Res. 2017;45:4036-4050 pubmed publisher
	Johnson R, Byrne A, Berger C, Klemm E, Crepin V, Dougan G, et al. The Type III Secretion System Effector SptP of Salmonella enterica Serovar Typhi. J Bacteriol. 2017;199: pubmed publisher
	Elkayam E, Parmar R, Brown C, Willoughby J, Theile C, Manoharan M, et al. siRNA carrying an (E)-vinylphosphonate moiety at the 5΄ end of the guide strand augments gene silencing by enhanced binding to human Argonaute-2. Nucleic Acids Res. 2017;45:3528-3536 pubmed publisher
	Davydova N, Harris N, Roufail S, Paquet Fifield S, Ishaq M, Streltsov V, et al. Differential Receptor Binding and Regulatory Mechanisms for the Lymphangiogenic Growth Factors Vascular Endothelial Growth Factor (VEGF)-C and -D. J Biol Chem. 2016;291:27265-27278 pubmed publisher
	Li B, Reddy S, Comai L. The Werner Syndrome Helicase Coordinates Sequential Strand Displacement and FEN1-Mediated Flap Cleavage during Polymerase δ Elongation. Mol Cell Biol. 2017;37: pubmed publisher
	Schenzel A, Klein C, Rist K, Moszner N, Barner Kowollik C. Reversing Adhesion: A Triggered Release Self-Reporting Adhesive. Adv Sci (Weinh). 2016;3:1500361 pubmed
	Svensson K, Heinz B, Schaus J, Beck J, Hao J, Krushinski J, et al. An Allosteric Potentiator of the Dopamine D1 Receptor Increases Locomotor Activity in Human D1 Knock-In Mice without Causing Stereotypy or Tachyphylaxis. J Pharmacol Exp Ther. 2017;360:117-128 pubmed
	Crosby C, Matchett W, Anguiano Zarate S, Parks C, Weaver E, Pease L, et al. Replicating Single-Cycle Adenovirus Vectors Generate Amplified Influenza Vaccine Responses. J Virol. 2017;91: pubmed publisher
	Ormanns S, Haas M, Baechmann S, Altendorf Hofmann A, Remold A, Quietzsch D, et al. Impact of SPARC expression on outcome in patients with advanced pancreatic cancer not receiving nab-paclitaxel: a pooled analysis from prospective clinical and translational trials. Br J Cancer. 2016;115:1520-1529 pubmed publisher
	Kong X, Chen L, Ye P, Wang Z, Zhang J, Ye F, et al. The role of HYAL2 in LSS-induced glycocalyx impairment and the PKA-mediated decrease in eNOS-Ser-633 phosphorylation and nitric oxide production. Mol Biol Cell. 2016;27:3972-3979 pubmed
	Zhang H, Wang P, Bisetto S, Yoon Y, Chen Q, Sheu S, et al. A novel fission-independent role of dynamin-related protein 1 in cardiac mitochondrial respiration. Cardiovasc Res. 2017;113:160-170 pubmed publisher
	Nabi H, Rashid I, Ahmad N, Durrani A, Akbar H, Islam S, et al. Induction of specific humoral immune response in mice immunized with ROP18 nanospheres from Toxoplasma gondii. Parasitol Res. 2017;116:359-370 pubmed
	Fine N, Dimitriou I, Rullo J, Sandi M, Petri B, Haitsma J, et al. GEF-H1 is necessary for neutrophil shear stress-induced migration during inflammation. J Cell Biol. 2016;215:107-119 pubmed
	Olabarria C, Gestoso I, Lima F, Vázquez E, Comeau L, Gomes F, et al. Response of Two Mytilids to a Heatwave: The Complex Interplay of Physiology, Behaviour and Ecological Interactions. PLoS ONE. 2016;11:e0164330 pubmed publisher
	Yi J, Manna A, Barr V, Hong J, Neuman K, Samelson L. madSTORM: a superresolution technique for large-scale multiplexing at single-molecule accuracy. Mol Biol Cell. 2016;27:3591-3600 pubmed
	Roche O, Deguiz M, Tiana M, Galiana Ribote C, Martinez Alcazar D, Rey Serra C, et al. Identification of non-coding genetic variants in samples from hypoxemic respiratory disease patients that affect the transcriptional response to hypoxia. Nucleic Acids Res. 2016;44:9315-9330 pubmed
	Blazer L, Li F, Kennedy S, Zheng Y, Arrowsmith C, Vedadi M. A Suite of Biochemical Assays for Screening RNA Methyltransferase BCDIN3D. SLAS Discov. 2017;22:32-39 pubmed publisher
	Aguet F, Upadhyayula S, Gaudin R, Chou Y, Cocucci E, He K, et al. Membrane dynamics of dividing cells imaged by lattice light-sheet microscopy. Mol Biol Cell. 2016;27:3418-3435 pubmed
	Tan C, McNaughton P. The TRPM2 ion channel is required for sensitivity to warmth. Nature. 2016;536:460-3 pubmed
	Gay G, Braun L, Brenier Pinchart M, Vollaire J, Josserand V, Bertini R, et al. Toxoplasma gondii TgIST co-opts host chromatin repressors dampening STAT1-dependent gene regulation and IFN-?-mediated host defenses. J Exp Med. 2016;213:1779-98 pubmed publisher
	Li Y, Fariss R, Qian J, Cohen E, Qian H. Light-Induced Thickening of Photoreceptor Outer Segment Layer Detected by Ultra-High Resolution OCT Imaging. Invest Ophthalmol Vis Sci. 2016;57:OCT105-11 pubmed publisher
	Das S, Lovicu F, Collinson E. Nox4 Plays a Role in TGF-?-Dependent Lens Epithelial to Mesenchymal Transition. Invest Ophthalmol Vis Sci. 2016;57:3665-73 pubmed publisher
	Mollet I, Malm H, Wendt A, Orho Melander M, Eliasson L. Integrator of Stress Responses Calmodulin Binding Transcription Activator 1 (Camta1) Regulates miR-212/miR-132 Expression and Insulin Secretion. J Biol Chem. 2016;291:18440-52 pubmed publisher
	Howes R, Battle K, Mendis K, Smith D, Cibulskis R, Baird J, et al. Global Epidemiology of Plasmodium vivax. Am J Trop Med Hyg. 2016;95:15-34 pubmed publisher
	More A, Mishra J, Hankins G, Kumar S. Prenatal Testosterone Exposure Decreases Aldosterone Production but Maintains Normal Plasma Volume and Increases Blood Pressure in Adult Female Rats. Biol Reprod. 2016;95:42 pubmed publisher
	Downey A, Hales B, Robaire B. Zinc Transport Differs in Rat Spermatogenic Cell Types and Is Affected by Treatment with Cyclophosphamide. Biol Reprod. 2016;95:22 pubmed publisher
	Smither B, Pang H, Brubaker P. Glucagon-Like Peptide-2 Requires a Full Complement of Bmi-1 for Its Proliferative Effects in the Murine Small Intestine. Endocrinology. 2016;157:2660-70 pubmed publisher
	Kasza A, Hunya A, Frank Z, Fulop F, Torok Z, Balogh G, et al. Dihydropyridine Derivatives Modulate Heat Shock Responses and have a Neuroprotective Effect in a Transgenic Mouse Model of Alzheimer's Disease. J Alzheimers Dis. 2016;53:557-71 pubmed publisher
	Anvarian Z, Nojima H, Van Kappel E, Madl T, Spit M, Viertler M, et al. Axin cancer mutants form nanoaggregates to rewire the Wnt signaling network. Nat Struct Mol Biol. 2016;23:324-32 pubmed publisher
	Bagheri Sereshki N, Hales B, Robaire B. The Effects of Chemotherapeutic Agents, Bleomycin, Etoposide, and Cisplatin, on Chromatin Remodeling in Male Rat Germ Cells. Biol Reprod. 2016;94:81 pubmed publisher
	Matsui M, Prakash T, Corey D. Argonaute 2-dependent Regulation of Gene Expression by Single-stranded miRNA Mimics. Mol Ther. 2016;24:946-55 pubmed publisher
	Levy S, Allerston C, Liveanu V, Habib M, Gileadi O, Schuster G. Identification of LACTB2, a metallo-Î²-lactamase protein, as a human mitochondrial endoribonuclease. Nucleic Acids Res. 2016;44:1813-32 pubmed publisher
	Sartain S, Turner N, Moake J. TNF Regulates Essential Alternative Complement Pathway Components and Impairs Activation of Protein C in Human Glomerular Endothelial Cells. J Immunol. 2016;196:832-45 pubmed publisher
	Willems C, Fu Q, Roose H, Mertens F, Cox B, Chen J, et al. Regeneration in the Pituitary After Cell-Ablation Injury: Time-Related Aspects and Molecular Analysis. Endocrinology. 2016;157:705-21 pubmed publisher
	Mani M, Lee U, Yoon N, Kim H, Ko M, Seol W, et al. Developmentally regulated GTP-binding protein 2 coordinates Rab5 activity and transferrin recycling. Mol Biol Cell. 2016;27:334-48 pubmed publisher
	Valcourt U, Carthy J, Okita Y, Alcaraz L, Kato M, Thuault S, et al. Analysis of Epithelial-Mesenchymal Transition Induced by Transforming Growth Factor Î². Methods Mol Biol. 2016;1344:147-81 pubmed publisher
	Mulcahy M, Blattman S, Barrantes F, Lukas R, Hawrot E. Resistance to Inhibitors of Cholinesterase 3 (Ric-3) Expression Promotes Selective Protein Associations with the Human Î±7-Nicotinic Acetylcholine Receptor Interactome. PLoS ONE. 2015;10:e0134409 pubmed publisher
	Dyson M, Kakinuma T, Pavone M, Monsivais D, Navarro A, Malpani S, et al. Aberrant expression and localization of deoxyribonucleic acid methyltransferase 3B in endometriotic stromal cells. Fertil Steril. 2015;104:953-963.e2 pubmed publisher
	Åšmieszek A, Czyrek A, Basińska K, Trynda J, SkaradziÅ„ska A, SiudziÅ„ska A, et al. Effect of Metformin on Viability, Morphology, and Ultrastructure of Mouse Bone Marrow-Derived Multipotent Mesenchymal Stromal Cells and Balb/3T3 Embryonic Fibroblast Cell Line. Biomed Res Int. 2015;2015:769402 pubmed publisher
	de Castro A, Minty F, Hattinger E, Wolf R, Parkinson E. The secreted protein S100A7 (psoriasin) is induced by telomere dysfunction in human keratinocytes independently of a DNA damage response and cell cycle regulators. Longev Healthspan. 2014;3:8 pubmed publisher
	Petry F, Pelletier J, Bretteville A, Morin F, Calon F, Hébert S, et al. Specificity of anti-tau antibodies when analyzing mice models of Alzheimer's disease: problems and solutions. PLoS ONE. 2014;9:e94251 pubmed publisher
	Klimovskaia I, Young C, Strømme C, Menard P, Jasencakova Z, Mejlvang J, et al. Tousled-like kinases phosphorylate Asf1 to promote histone supply during DNA replication. Nat Commun. 2014;5:3394 pubmed publisher
	Sunico C, Nakamura T, Rockenstein E, Mante M, Adame A, Chan S, et al. S-Nitrosylation of parkin as a novel regulator of p53-mediated neuronal cell death in sporadic Parkinson's disease. Mol Neurodegener. 2013;8:29 pubmed publisher
	Lahmy V, Meunier J, Malmström S, Naert G, Givalois L, Kim S, et al. Blockade of Tau hyperphosphorylation and A????? generation by the aminotetrahydrofuran derivative ANAVEX2-73, a mixed muscarinic and ?? receptor agonist, in a nontransgenic mouse model of Alzheimer's disease. Neuropsychopharmacology. 2013;38:1706-23 pubmed publisher
	Schwartz J, Lee C, Hiatt J, Adey A, Shendure J. Capturing native long-range contiguity by in situ library construction and optical sequencing. Proc Natl Acad Sci U S A. 2012;109:18749-54 pubmed publisher
	King B, Cooper K, Liu K, Hudson L. Poly(ADP-ribose) contributes to an association between poly(ADP-ribose) polymerase-1 and xeroderma pigmentosum complementation group A in nucleotide excision repair. J Biol Chem. 2012;287:39824-33 pubmed publisher
	Chisholm D, Naci H, Hyder A, Tran N, Peden M. Cost effectiveness of strategies to combat road traffic injuries in sub-Saharan Africa and South East Asia: mathematical modelling study. BMJ. 2012;344:e612 pubmed publisher
	Migdall Wilson J, Bates C, Schlegel J, BRANDAO L, Linger R, DeRyckere D, et al. Prolonged exposure to a Mer ligand in leukemia: Gas6 favors expression of a partial Mer glycoform and reveals a novel role for Mer in the nucleus. PLoS ONE. 2012;7:e31635 pubmed publisher
	Ge R, Wang Z, Zeng Q, Xu X, Olumi A. F-box protein 10, an NF-?B-dependent anti-apoptotic protein, regulates TRAIL-induced apoptosis through modulating c-Fos/c-FLIP pathway. Cell Death Differ. 2011;18:1184-95 pubmed publisher
	Chayka O, Corvetta D, Dews M, Caccamo A, Piotrowska I, Santilli G, et al. Clusterin, a haploinsufficient tumor suppressor gene in neuroblastomas. J Natl Cancer Inst. 2009;101:663-77 pubmed publisher
	Nicholson T, Stanners C. Specific inhibition of GPI-anchored protein function by homing and self-association of specific GPI anchors. J Cell Biol. 2006;175:647-59 pubmed
	Islas L, Zagotta W. Short-range molecular rearrangements in ion channels detected by tryptophan quenching of bimane fluorescence. J Gen Physiol. 2006;128:337-46 pubmed
	Minamoto K, Harada H, Lama V, Fedarau M, Pinsky D. Reciprocal regulation of airway rejection by the inducible gas-forming enzymes heme oxygenase and nitric oxide synthase. J Exp Med. 2005;202:283-94 pubmed
	Harris F, Brecht W, Xu Q, Mahley R, Huang Y. Increased tau phosphorylation in apolipoprotein E4 transgenic mice is associated with activation of extracellular signal-regulated kinase: modulation by zinc. J Biol Chem. 2004;279:44795-801 pubmed
	Smith M, Rounds C, Wang F, Chen K, Afitlhile M, Schnell D. atToc159 is a selective transit peptide receptor for the import of nucleus-encoded chloroplast proteins. J Cell Biol. 2004;165:323-34 pubmed
	Brecht W, Harris F, Chang S, Tesseur I, Yu G, Xu Q, et al. Neuron-specific apolipoprotein e4 proteolysis is associated with increased tau phosphorylation in brains of transgenic mice. J Neurosci. 2004;24:2527-34 pubmed
	Fujikawa K, Miletic A, Alt F, Faccio R, Brown T, Hoog J, et al. Vav1/2/3-null mice define an essential role for Vav family proteins in lymphocyte development and activation but a differential requirement in MAPK signaling in T and B cells. J Exp Med. 2003;198:1595-608 pubmed
	Manes S, Mira E, Colomer R, Montero S, Real L, Gomez Mouton C, et al. CCR5 expression influences the progression of human breast cancer in a p53-dependent manner. J Exp Med. 2003;198:1381-9 pubmed
	Harris F, Brecht W, Xu Q, Tesseur I, Kekonius L, Wyss Coray T, et al. Carboxyl-terminal-truncated apolipoprotein E4 causes Alzheimer's disease-like neurodegeneration and behavioral deficits in transgenic mice. Proc Natl Acad Sci U S A. 2003;100:10966-71 pubmed
	Wittmann T, Bokoch G, Waterman Storer C. Regulation of leading edge microtubule and actin dynamics downstream of Rac1. J Cell Biol. 2003;161:845-51 pubmed
	Yoshida H, Goedert M. Molecular cloning and functional characterization of chicken brain tau: isoforms with up to five tandem repeats. Biochemistry. 2002;41:15203-11 pubmed
	Sahara N, Lewis J, Deture M, McGowan E, Dickson D, Hutton M, et al. Assembly of tau in transgenic animals expressing P301L tau: alteration of phosphorylation and solubility. J Neurochem. 2002;83:1498-508 pubmed
	Deture M, Ko L, Easson C, Yen S. Tau assembly in inducible transfectants expressing wild-type or FTDP-17 tau. Am J Pathol. 2002;161:1711-22 pubmed
	Li Y, Wang M, Li H, King K, Bassi R, Sun H, et al. Active immunization against the vascular endothelial growth factor receptor flk1 inhibits tumor angiogenesis and metastasis. J Exp Med. 2002;195:1575-84 pubmed
	Carvalho T, Mota Santos T, Cumano A, Demengeot J, Vieira P. Arrested B lymphopoiesis and persistence of activated B cells in adult interleukin 7(-/)- mice. J Exp Med. 2001;194:1141-50 pubmed
	Huang Y, Liu X, Wyss Coray T, Brecht W, Sanan D, Mahley R. Apolipoprotein E fragments present in Alzheimer's disease brains induce neurofibrillary tangle-like intracellular inclusions in neurons. Proc Natl Acad Sci U S A. 2001;98:8838-43 pubmed
	Tseng S, Otsuji M, Gorski K, Huang X, Slansky J, Pai S, et al. B7-DC, a new dendritic cell molecule with potent costimulatory properties for T cells. J Exp Med. 2001;193:839-46 pubmed
	Gretz J, Norbury C, Anderson A, Proudfoot A, Shaw S. Lymph-borne chemokines and other low molecular weight molecules reach high endothelial venules via specialized conduits while a functional barrier limits access to the lymphocyte microenvironments in lymph node cortex. J Exp Med. 2000;192:1425-40 pubmed
	Briken V, Jackman R, Watts G, Rogers R, Porcelli S. Human CD1b and CD1c isoforms survey different intracellular compartments for the presentation of microbial lipid antigens. J Exp Med. 2000;192:281-8 pubmed
	Nimigean C, Magleby K. Functional coupling of the beta(1) subunit to the large conductance Ca(2+)-activated K(+) channel in the absence of Ca(2+). Increased Ca(2+) sensitivity from a Ca(2+)-independent mechanism. J Gen Physiol. 2000;115:719-36 pubmed
	Korner H, Cretney E, Wilhelm P, Kelly J, Rollinghoff M, Sedgwick J, et al. Tumor necrosis factor sustains the generalized lymphoproliferative disorder (gld) phenotype. J Exp Med. 2000;191:89-96 pubmed
	Goedert M, Jakes R, Crowther R, Cohen P, Vanmechelen E, Vandermeeren M, et al. Epitope mapping of monoclonal antibodies to the paired helical filaments of Alzheimer's disease: identification of phosphorylation sites in tau protein. Biochem J. 1994;301 ( Pt 3):871-7 pubmed

product information

Product Type :

Antibody

Product Name :

Phospho-Tau (Thr212, Ser214) Monoclonal Antibody (AT100)

Catalog # :

MN1060

Quantity :

100 µg

Price :

US 588

Clonality :

Monoclonal

Purity :

protein A

Host :

Mouse

Reactivity :

Human

Applications :

ELISA: 5-10 µg/mL, Immunohistochemistry (Paraffin): 1-5 µg/mL, Western Blot: 1-5 µg/mL

Species :

Human

Clone :

AT100

Isotype :

IgG1, kappa

Storage :

-20° C, Avoid Freeze/Thaw Cycles

Description :

Tau is a neuronal microtubule-associated protein found predominantly on axons. The function of Tau is to promote tubulin polymerization and stabilize microtubules. The C-terminus binds axonal microtubules while the N- terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by TAU/MAPT localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton while the longer isoforms may preferentially play a role in its stabilization. In its hyper-phosphorylated form, Tau is the major component of paired helical filaments (PHF), the building block of neurofibrillary lesions in Alzheimer's diseases (AD) brain. Hyper-phosphorylation impairs the microtubule binding function of Tau, resulting in the destabilization of microtubules in AD brains, ultimately leading to the degeneration of the affected neurons. Numerous serine/threonine kinases phosphorylate Tau, including GSK-3beta, protein kinase A (PKA), cyclin-dependent kinase 5 (cdk5) and casein kinase II. Hyper-phosphorylated Tau is found in neurofibrillary lesions in a range and other central nervous system disorders such as Pick's disease, frontotemporal dementia, cortico-basal degeneration and progressive supranuclear palsy.

Immunogen :

Purified human Tau

Format :

Liquid

Applications w/Dilutions :

ELISA: 5-10 µg/mL, Immunohistochemistry (Paraffin): 1-5 µg/mL, Western Blot: 1-5 µg/mL

Aliases :

AI413597; AW045860; DDPAC; FLJ31424; FTDP17; FTDP-17; G protein beta1/gamma2 subunit-interacting factor 1; map tau; Mapt; MAPTL; MGC138549; microtubule associated protein tau; microtubule-associated protein tau; microtubule-associated protein tau, isoform 4; microtubules; MSTD; Mtapt; MTBT1; MTBT2; Neurofibrillary tangle protein; neurofibrillary tangles; Neuronal Marker; paired helical filament-tau; PHFtau; PHF-tau; PPND; PPP1R103; protein phosphatase 1, regulatory subunit 103; pTau; RNPTAU; Tau; Tau microtubule-associated protein; tau protein; Tau-4; Tau5; Unknown (protein for MGC:134287)

more info or order :

Invitrogen product webpage