This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
IL-5 Monoclonal Antibody (TRFK5), Biotin
catalog :
MM550CB
quantity :
250 ug
price :
US 520.00
clonality :
monoclonal
host :
rat
conjugate :
biotin
clone name :
TRFK5

The same clone is also sold as:
reactivity :
mouse
application :
western blot, ELISA, blocking or activating experiments
citations: 17
Reference
Zhang K, Fang Y, He Y, Yin H, Guan X, Pu Y, et al. Extravascular gelation shrinkage-derived internal stress enables tumor starvation therapy with suppressed metastasis and recurrence. Nat Commun. 2019;10:5380 pubmed publisher
Liao K, Meyer E, Lee T, Loercher A, Sikkema D. Inhibition of interleukin-5 induced false positive anti-drug antibody responses against mepolizumab through the use of a competitive blocking antibody. J Immunol Methods. 2017;441:15-23 pubmed publisher
Sakamoto Y, Hiromatsu K, Ishiwata K, Inagaki Ohara K, Ikeda T, Nakamura Uchiyama F, et al. Chronic intestinal nematode infection induces Stat6-independent interleukin-5 production and causes eosinophilic inflammatory responses in mice. Immunology. 2004;112:615-23 pubmed
Chen M, Hu K, Rozell B, Orvell C, Morein B, Liljestrom P. Vaccination with recombinant alphavirus or immune-stimulating complex antigen against respiratory syncytial virus. J Immunol. 2002;169:3208-16 pubmed
Fernvik E, Peltre G, Senechal H, Vargaftig B. Effects of birch pollen and traffic particulate matter on Th2 cytokines, immunoglobulin E levels and bronchial hyper-responsiveness in mice. Clin Exp Allergy. 2002;32:602-11 pubmed
Ichinose T, Takano H, Miyabara Y, Sagai M. Long-term exposure to diesel exhaust enhances antigen-induced eosinophilic inflammation and epithelial damage in the murine airway. Toxicol Sci. 1998;44:70-9 pubmed
Bordmann G, Rudin W, Favre N. Immunization of mice with phosphatidylcholine drastically reduces the parasitaemia of subsequent Plasmodium chabaudi chabaudi blood-stage infections. Immunology. 1998;94:35-40 pubmed
Takano H, Lim H, Miyabara Y, Ichinose T, Yoshikawa T, Sagai M. Oral administration of L-arginine potentiates allergen-induced airway inflammation and expression of interleukin-5 in mice. J Pharmacol Exp Ther. 1998;286:767-71 pubmed
Hogarth P, Taylor M, Bianco A. IL-5-dependent immunity to microfilariae is independent of IL-4 in a mouse model of onchocerciasis. J Immunol. 1998;160:5436-40 pubmed
Miyabara Y, Yanagisawa R, Shimojo N, Takano H, Lim H, Ichinose T, et al. Murine strain differences in airway inflammation caused by diesel exhaust particles. Eur Respir J. 1998;11:291-8 pubmed
Yang J, Torio A, Donoff R, Gallagher G, Egan R, Weller P, et al. Depletion of eosinophil infiltration by anti-IL-5 monoclonal antibody (TRFK-5) accelerates open skin wound epithelial closure. Am J Pathol. 1997;151:813-9 pubmed
Takano H, Yoshikawa T, Ichinose T, Miyabara Y, Imaoka K, Sagai M. Diesel exhaust particles enhance antigen-induced airway inflammation and local cytokine expression in mice. Am J Respir Crit Care Med. 1997;156:36-42 pubmed
Fowler D, Breglio J, Nagel G, Eckhaus M, Gress R. Allospecific CD8+ Tc1 and Tc2 populations in graft-versus-leukemia effect and graft-versus-host disease. J Immunol. 1996;157:4811-21 pubmed
Suzue K, Young R. Adjuvant-free hsp70 fusion protein system elicits humoral and cellular immune responses to HIV-1 p24. J Immunol. 1996;156:873-9 pubmed
Lin H, Mosmann T, Guilbert L, Tuntipopipat S, Wegmann T. Synthesis of T helper 2-type cytokines at the maternal-fetal interface. J Immunol. 1993;151:4562-73 pubmed
Stevenson M, Tam M, Wolf S, Sher A. IL-12-induced protection against blood-stage Plasmodium chabaudi AS requires IFN-gamma and TNF-alpha and occurs via a nitric oxide-dependent mechanism. J Immunol. 1995;155:2545-56 pubmed
Mosmann T, Schumacher J, Fiorentino D, Leverah J, Moore K, Bond M. Isolation of monoclonal antibodies specific for IL-4, IL-5, IL-6, and a new Th2-specific cytokine (IL-10), cytokine synthesis inhibitory factor, by using a solid phase radioimmunoadsorbent assay. J Immunol. 1990;145:2938-45 pubmed
product information
Product Type :
Antibody
Product Name :
IL-5 Monoclonal Antibody (TRFK5), Biotin
Catalog # :
MM550CB
Quantity :
250 ug
Price :
US 520.00
Clonality :
Monoclonal
Purity :
Protein G
Host :
Rat
Reactivity :
Mouse
Applications :
ELISA: Assay-dependent, Western Blot: Assay-dependent
Species :
Mouse
Clone :
TRFK5
Isotype :
IgG1
Storage :
-20 C
Description :
IL-5 is a cytokine that acts as a growth and differentiation factor for both B cells and eosinophils. IL-5 cytokine is a main regulator of eosinopoiesis, eosinophil maturation and activation. The elevated production of this cytokine is reported to be related to asthma or hypereosinophilic syndromes. The receptor of IL-5 cytokine is a heterodimer, whose beta subunit is shared with the receptors for interleukine 3 (IL3) and colony stimulating factor 2 (CSF2/GM-CSF). IL-5, together with those for interleukin 4 (IL4), interleukin 13 (IL13), and CSF2, form a cytokine gene cluster on chromosome 5. IL-5, IL4, and IL13 are found to be regulated coordinately by long-range regulatory elements spread over 120 kilobases on chromosome 5q31.
Immunogen :
Recombinant mouse IL-5
Format :
Liquid
Applications w/Dilutions :
ELISA: Assay-dependent, Western Blot: Assay-dependent
Aliases :
B-cell differentiation factor I; B-cell growth factor II; BCGF-II; colony-stimulating factor, eosinophil; cytotoxic T-lymphocyte inducer; EDF; Eosinophil differentiation factor; IL5; IL-5; ILN; Interleukin; Interleukin 5; Interleukin 5 (colony-stimulating factor eosinophil); Interleukin 5 (colony-stimulating factor, eosinophil); Interleukin5; interleukin-5; T-cell replacing factor; TRF
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA