GM-CSF Monoclonal Antibody (31G6), Biotin | Invitrogen MM500DB product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

GM-CSF Monoclonal Antibody (31G6), Biotin

catalog :

MM500DB

quantity :

250 ug

price :

US 451.00

clonality :

monoclonal

host :

rat

conjugate :

biotin

clone name :

31G6

reactivity :

mouse

application :

western blot

citations: 2

Reference
Cakouros D, Cockerill P, Bert A, Mital R, Roberts D, Shannon M. A NF-kappa B/Sp1 region is essential for chromatin remodeling and correct transcription of a human granulocyte-macrophage colony-stimulating factor transgene. J Immunol. 2001;167:302-10 pubmed
Tiegs G, Barsig J, Matiba B, Uhlig S, Wendel A. Potentiation by granulocyte macrophage colony-stimulating factor of lipopolysaccharide toxicity in mice. J Clin Invest. 1994;93:2616-22 pubmed

product information

Product Type :

Antibody

Product Name :

GM-CSF Monoclonal Antibody (31G6), Biotin

Catalog # :

MM500DB

Quantity :

250 ug

Price :

US 451.00

Clonality :

Monoclonal

Purity :

Protein G

Host :

Rat

Reactivity :

Mouse

Applications :

Western Blot: Assay-dependent

Species :

Mouse

Clone :

31G6

Isotype :

IgG1

Storage :

-20 C

Description :

The GM-CSF gene encodes for a cytokine that regulates the production, differentiation, and function of macrophages and granulocytes. The active form of the protein exists as a homodimer in the extracellular space. This gene is located in a cluster of related genes at the chromosome region 5q31, which has been associated with interstitial deletions in the 5q- syndrome and acute myelogenous leukemia. Other genes in the cluster include interleukins 4, 5, and 13. The gene is involved in promoting tissue inflammation. Elevated levels of cytokines, including the one produced by this gene, have been observed in SARS-CoV-2 infected patients with acute respiratory distress syndrome. Mice that lack this gene or its receptor have been shown to develop pulmonary alveolar proteinosis.

Immunogen :

Recombinant mouse GM-CSF

Format :

Liquid

Applications w/Dilutions :

Western Blot: Assay-dependent

Aliases :

colony stimulating factor 2; colony stimulating factor 2 (granulocyte-macrophage); colony-stimulating factor; CSF; CSF2; Csfgm; cytokine; GMCSF; Gm-CSf; granulocyte macrophage colony stimulating factor; granulocyte macrophage-colony stimulating factor; granulocyte-macrophage colony stimulating factor 2; granulocyte-macrophage colony-stimulating factor; MGC131935; MGC138897; MGC151255; MGC151257; MGI-IGM; M-GM-CSF; molgramostin; put. GM-CSF; sargramostim