IL-2 Monoclonal Antibody (1A12), Biotin | Invitrogen MM102B product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

IL-2 Monoclonal Antibody (1A12), Biotin

catalog :

MM102B

quantity :

250 µg

price :

US 400.00

clonality :

monoclonal

host :

rat

conjugate :

biotin

clone name :

1A12

reactivity :

mouse

application :

western blot, ELISA, blocking or activating experiments

more info or order :

Invitrogen product webpage

citations: 17

Published Application/Species/Sample/Dilution	Reference
ELISA; mouse; loading ...; fig 3a	Johnson R, Yu H, Strank N, Karunakaran K, Zhu Y, Brunham R. B Cell Presentation of Chlamydia Antigen Selects Out Protective CD4?13 T Cells: Implications for Genital Tract Tissue-Resident Memory Lymphocyte Clusters. Infect Immun. 2018;86: pubmed publisher
blocking or activating experiments; mouse; loading ...; fig s4a	Tripathi D, Venkatasubramanian S, Cheekatla S, Paidipally P, Welch E, Tvinnereim A, et al. A TLR9 agonist promotes IL-22-dependent pancreatic islet allograft survival in type 1 diabetic mice. Nat Commun. 2016;7:13896 pubmed publisher
ELISA; mouse; loading ...; fig 6	Silberman D, Krovi S, Tuttle K, Crooks J, Reisdorph R, White J, et al. Class II major histocompatibility complex mutant mice to study the germ-line bias of T-cell antigen receptors. Proc Natl Acad Sci U S A. 2016;113:E5608-17 pubmed publisher
blocking or activating experiments; mouse	Sekiya T, Yoshimura A. In Vitro Th Differentiation Protocol. Methods Mol Biol. 2016;1344:183-91 pubmed publisher
ELISA; mouse; fig 3	Uchiyama M, Jin X, Yin E, Shimokawa T, Niimi M. Treadmill exercise induces murine cardiac allograft survival and generates regulatory T cell. Transpl Int. 2015;28:352-62 pubmed publisher
ELISA; mouse	Johnson R, Kerr M, Slaven J. An atypical CD8 T-cell response to Chlamydia muridarum genital tract infections includes T cells that produce interleukin-13. Immunology. 2014;142:248-57 pubmed publisher
ELISA; mouse; fig 3	Jin X, Uchiyama M, Zhang Q, Hirai T, Niimi M. Inchingorei-san (TJ-117) and Artemisiae Capillaris Herba Induced Prolonged Survival of Fully Mismatched Cardiac Allografts and Generated Regulatory Cells in Mice. Evid Based Complement Alternat Med. 2012;2012:689810 pubmed publisher
ELISA; mouse; fig 3	Uchiyama M, Jin X, Zhang Q, Hirai T, Amano A, Bashuda H, et al. Auditory stimulation of opera music induced prolongation of murine cardiac allograft survival and maintained generation of regulatory CD4+CD25+ cells. J Cardiothorac Surg. 2012;7:26 pubmed publisher
ELISA; mouse	Johnson R, Yu H, Kerr M, Slaven J, Karunakaran K, Brunham R. PmpG303-311, a protective vaccine epitope that elicits persistent cellular immune responses in Chlamydia muridarum-immune mice. Infect Immun. 2012;80:2204-11 pubmed publisher
ELISA; mouse	Johnson R, Kerr M, Slaven J. Plac8-dependent and inducible NO synthase-dependent mechanisms clear Chlamydia muridarum infections from the genital tract. J Immunol. 2012;188:1896-904 pubmed publisher
ELISA; mouse; 500 ug/ml	Debierre Grockiego F, Molitor N, Schwarz R, Lüder C. Toxoplasma gondii glycosylphosphatidylinositols up-regulate major histocompatibility complex (MHC) molecule expression on primary murine macrophages. Innate Immun. 2009;15:25-32 pubmed publisher
ELISA; mouse; 0.5 ug/ml; tbl 4	Heinz R, Waltenbaugh C. Ethanol consumption modifies dendritic cell antigen presentation in mice. Alcohol Clin Exp Res. 2007;31:1759-71 pubmed
ELISA; mouse; fig 4	Aramaki O, Shirasugi N, Takayama T, Shimazu M, Kitajima M, Ikeda Y, et al. Programmed death-1-programmed death-L1 interaction is essential for induction of regulatory cells by intratracheal delivery of alloantigen. Transplantation. 2004;77:6-12 pubmed
	Tokoyoda K, Tsujikawa K, Matsushita H, Ono Y, Hayashi T, Harada Y, et al. Up-regulation of IL-4 production by the activated cAMP/cAMP-dependent protein kinase (protein kinase A) pathway in CD3/CD28-stimulated naive T cells. Int Immunol. 2004;16:643-53 pubmed
	Assenmacher M, Lohning M, Scheffold A, Richter A, Miltenyi S, Schmitz J, et al. Commitment of individual Th1-like lymphocytes to expression of IFN-gamma versus IL-4 and IL-10: selective induction of IL-10 by sequential stimulation of naive Th cells with IL-12 and IL-4. J Immunol. 1998;161:2825-32 pubmed
	DeKruyff R, Fang Y, Umetsu D. Corticosteroids enhance the capacity of macrophages to induce Th2 cytokine synthesis in CD4+ lymphocytes by inhibiting IL-12 production. J Immunol. 1998;160:2231-7 pubmed
	Goedert S, Germann T, Hoehn P, Koelsch S, Palm N, Rude E, et al. Th1 development of naive CD4+ T cells is inhibited by co-activation with anti-CD4 monoclonal antibodies. J Immunol. 1996;157:566-73 pubmed

product information

Product Type :

Antibody

Product Name :

IL-2 Monoclonal Antibody (1A12), Biotin

Catalog # :

MM102B

Quantity :

250 µg

Price :

US 400.00

Clonality :

Monoclonal

Purity :

Caprylic acid precipitation

Host :

Rat

Reactivity :

Mouse

Applications :

ELISA: Assay-dependent, Western Blot: Assay-dependent

Species :

Mouse

Clone :

1A12

Isotype :

IgG2a

Storage :

-20°C

Description :

Interleukin 2 (IL-2) is an immuno-modulatory cytokine that is important for the proliferation of activated T cells, differentiation of B cells, natural killer cells, monocytes and macrophages. IL-2 signals through the IL-2 receptor (IL-2R), a heterotrimeric protein complex whose gamma chain is also shared by interleukin 4 (IL-4) and interleukin 7 (IL-7). The expression of the IL-2 gene in mature thymocytes is monoallelic, which represents an unusual regulatory mode for controlling the precise expression of a single gene. The targeted disruption of a gene similar to IL-2 in mice leads to an ulcerative colitis-like disease that suggests an essential role of this gene in the immune response to antigenic stimuli.

Immunogen :

Recombinant mouse IL-2

Format :

Liquid

Applications w/Dilutions :

ELISA: Assay-dependent, Western Blot: Assay-dependent

Aliases :

aldesleukin; cytokine; H-IL-2; il 2; Il2; Il-2; ILN; Interleukin; interleukin 2; interleukin 2 precursor; interleukin 2 variant IL2delta2; Interleukin2; Interleukin-2; interleukin-2 precursor; interleukin-2 precursor protein; interleukin-2; interleukin 2; Involved in regulation of T cell clonal expansion; involved in regulation of T-cell clonal expansion; lymphokine; M-IL-2; patial sequence of Interleukin-2; POIL2; porcine Interleukin 2; T cell growth factor; T-cell growth factor; T-cell growth factor (TCGF); TCGF

more info or order :

Invitrogen product webpage