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company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
Ki-67 Monoclonal Antibody (7B11), FITC
catalog :
MHKI6701
quantity :
500 uL
price :
US 333.00
clonality :
monoclonal
host :
mouse
conjugate :
FITC
clone name :
7B11
reactivity :
human
application :
flow cytometry
more info or order :
citations: 8
Published Application/Species/Sample/DilutionReference
  • flow cytometry; human; fig 4b
Weingartner E, Courneya J, Keegan A, Golding A. A novel method for assaying human regulatory T cell direct suppression of B cell effector function. J Immunol Methods. 2017;441:1-7 pubmed publisher
  • flow cytometry; human; fig 2
Zeniou M, Fève M, Mameri S, Dong J, Salomé C, Chen W, et al. Chemical Library Screening and Structure-Function Relationship Studies Identify Bisacodyl as a Potent and Selective Cytotoxic Agent Towards Quiescent Human Glioblastoma Tumor Stem-Like Cells. PLoS ONE. 2015;10:e0134793 pubmed publisher
Csordas B, de Sousa Palmeira P, Peixoto R, Comberlang F, de Medeiros I, Azevedo F, et al. Is IFN expression by NK cells a hallmark of severe COVID-19?. Cytokine. 2022;157:155971 pubmed publisher
Garimalla S, Nguyen D, Halliley J, Tipton C, Rosenberg A, Fucile C, et al. Differential transcriptome and development of human peripheral plasma cell subsets. JCI Insight. 2019;4: pubmed publisher
Tanko R, Soares A, Müller T, Garrett N, Samsunder N, Abdool Karim Q, et al. Effect of Antiretroviral Therapy on the Memory and Activation Profiles of B Cells in HIV-Infected African Women. J Immunol. 2017;198:1220-1228 pubmed publisher
Zhao M, Tominaga Y, Ohuchida K, Mizumoto K, Cui L, Kozono S, et al. Significance of combination therapy of zoledronic acid and gemcitabine on pancreatic cancer. Cancer Sci. 2012;103:58-66 pubmed publisher
Ko S, Ueno T, Yoshimoto Y, Yoo J, Abdel Wahab O, Abdel Wahab Z, et al. Optimizing a novel regional chemotherapeutic agent against melanoma: hyperthermia-induced enhancement of temozolomide cytotoxicity. Clin Cancer Res. 2006;12:289-97 pubmed
Pinto A, Andre S, Pereira T, Nobrega S, Soares J. Prognostic comparative study of S-phase fraction and Ki-67 index in breast carcinoma. J Clin Pathol. 2001;54:543-9 pubmed
product information
Product Type :
Antibody
Product Name :
Ki-67 Monoclonal Antibody (7B11), FITC
Catalog # :
MHKI6701
Quantity :
500 uL
Price :
US 333.00
Clonality :
Monoclonal
Purity :
purified
Host :
Mouse
Reactivity :
Human
Applications :
Flow Cytometry: Assay-Dependent
Species :
Human
Clone :
7B11
Isotype :
IgG1, kappa
Storage :
4 C, store in dark
Description :
Ki-67 is a nuclear protein that is expressed during various stages in the cell cycle, particularly during late G1, S, G2, and M phases. The protein has a forkhead associated domain (FHA) through which it associates with euchromatin at the perichromosomal layer, the centromeric heterochromatin, and the nucleolus. Ki-67 is shown to have a cell cycle dependent topographical distribution with perinucleolar expression at G1, expression in the nuclear matrix at G2, and expression on the chromosomes during M phase. Ki-67 is commonly used as a proliferation marker because it is not detected in G0 cells, but increases steadily from G1 through mitosis. Ki-67 antibodies are useful in establishing the cell growing fraction in neoplasms. In neoplastic tissues, the prognostic value is comparable to the tritiated thymidine-labelling index. The correlation between low Ki-67 index and histologically low-grade tumors is strong. Ki-67 is routinely used as a neuronal marker of cell cycling and proliferation.
Immunogen :
Ki-67 synthetic peptide
Format :
Liquid
Applications w/Dilutions :
Flow Cytometry: Assay-Dependent
Aliases :
antigen identified by monoclonal antibody Ki 67; antigen identified by monoclonal antibody Ki-67; Antigen identified by monoclonal antibody Ki-67 homolog; Antigen KI-67; Antigen KI-67 homolog; antigen KI-67; proliferation marker protein Ki-67; antigen KI-67-like; cb31; D630048A14Rik; I79_022666; Ki67; Ki-67; KIA; LOW QUALITY PROTEIN: proliferation marker protein Ki-67; marker of proliferation Ki-67; MIB-; MIB-1; Mki67; PPP1R105; Proliferation marker protein Ki-67; proliferation-related Ki-67 antigen; protein phosphatase 1, regulatory subunit 105; RP11-380J17.2; sb:cb31; si:ch211-250b22.7; unnamed protein product; wu:fa11g09; wu:fb57a07; wu:fi14e05
more info or order :
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA