CD69 Monoclonal Antibody (CH/4), PE-Cyanine5.5 | Invitrogen MHCD6918 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CD69 Monoclonal Antibody (CH/4), PE-Cyanine5.5

catalog :

MHCD6918

quantity :

500 uL

price :

US 502.00

clonality :

monoclonal

host :

mouse

conjugate :

PE-Cy5.5

clone name :

CH/4

reactivity :

human

application :

flow cytometry

more info or order :

Invitrogen product webpage

citations: 6

Published Application/Species/Sample/Dilution	Reference
flow cytometry; human	Paich H, Sheridan P, Handy J, Karlsson E, Schultz Cherry S, Hudgens M, et al. Overweight and obese adult humans have a defective cellular immune response to pandemic H1N1 influenza A virus. Obesity (Silver Spring). 2013;21:2377-86 pubmed publisher
	Lee K, Thompson E, Gharaie S, Patel C, Kurzhagen J, Pierorazio P, et al. T cell metabolic reprogramming in acute kidney injury and protection by glutamine blockade. JCI Insight. 2023;8: pubmed publisher
	Okoye A, Fromentin R, Takata H, Brehm J, Fukazawa Y, Randall B, et al. The ingenol-based protein kinase C agonist GSK445A is a potent inducer of HIV and SIV RNA transcription. PLoS Pathog. 2022;18:e1010245 pubmed publisher
	Thompson E, Cascino K, Ordonez A, Zhou W, Vaghasia A, Hamacher Brady A, et al. Metabolic programs define dysfunctional immune responses in severe COVID-19 patients. Cell Rep. 2021;34:108863 pubmed publisher
	Okoye A, Duell D, Fukazawa Y, Varco Merth B, Marenco A, Behrens H, et al. CD8+ T cells fail to limit SIV reactivation following ART withdrawal until after viral amplification. J Clin Invest. 2021;131: pubmed publisher
	Guan C, Li Q, Song X, Xu W, Li L, Xu A. Antroquinonol Exerts Immunosuppressive Effect on CD8+ T Cell Proliferation and Activation to Resist Depigmentation Induced by H2O2. Oxid Med Cell Longev. 2017;2017:9303054 pubmed publisher

product information

Product Type :

Antibody

Product Name :

CD69 Monoclonal Antibody (CH/4), PE-Cyanine5.5

Catalog # :

MHCD6918

Quantity :

500 uL

Price :

US 502.00

Clonality :

Monoclonal

Purity :

purified

Host :

Mouse

Reactivity :

Human

Applications :

Flow Cytometry: Assay-Dependent

Species :

Human

Clone :

CH/4

Isotype :

IgG2a

Storage :

4 C, store in dark

Description :

CD69 (AIM, Active Inducer Molecule) is a gp28/34 disulfide bonded homodimer with a molecular weight of 60 kDa under non-reducing conditions. CD69 contains one or two N linked oligosacaride and the molecule is present on activated platelets. In normal peripheral blood a variable percentage of cells express the CD69 antigen, and it is involved in lymphocyte signal transduction. Expression CD69 is induced upon activation of T lymphocytes, and may play a role in proliferation. Furthermore, the protein may act to transmit signals in natural killer cells and platelets. Alternative splicing results in multiple transcript variants of CD69. Diseases associated with CD69 dysfunction include coccidiodomycosis and asthma.

Immunogen :

Human CD69

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: Assay-Dependent

Aliases :

5830438K24Rik; Activation inducer molecule; activation inducer molecule (AIM/CD69); AI452015; AIM; BL-AC/P26; CD69; CD69 antigen; CD69 antigen (p60, early T-cell activation antigen); CD69 molecule; CLEC2C; C-type lectin domain family 2 member C; C-type lectin domain family 2, member C; EA1; early activation antigen CD69; early lymphocyte activation antigen; early T-cell activation antigen p60; GP32/28; leukocyte surface antigen Leu-23; MLR-3; VEA; Very Early Activation Antigen

more info or order :

Invitrogen product webpage