product summary
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company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
CD69 Monoclonal Antibody (CH/4), PE
catalog :
MHCD6904
quantity :
500 µL
price :
US 386.00
clonality :
monoclonal
host :
mouse
conjugate :
PE
clone name :
CH/4
reactivity :
African green monkey, human, rhesus macaque
application :
flow cytometry
more info or order :
citations: 11
Published Application/Species/Sample/DilutionReference
  • flow cytometry; human
Zhang M, Ma Z, Selliah N, Weiss G, Genin A, Finkel T, et al. The impact of Nucleofection® on the activation state of primary human CD4 T cells. J Immunol Methods. 2014;408:123-31 pubmed publisher
  • flow cytometry; human; fig 2
Horowitz A, Riley E. Activation of human NK cells by Plasmodium-infected red blood cells. Methods Mol Biol. 2013;923:447-64 pubmed
  • flow cytometry; human; fig 7
Horowitz A, Behrens R, Okell L, Fooks A, Riley E. NK cells as effectors of acquired immune responses: effector CD4+ T cell-dependent activation of NK cells following vaccination. J Immunol. 2010;185:2808-18 pubmed publisher
  • flow cytometry; human; fig 29.2
Horowitz A, Riley E. Activation of human NK cells by malaria-infected red blood cells. Methods Mol Biol. 2010;612:429-46 pubmed publisher
  • flow cytometry; human; fig 4
Hantschel O, Gstoettenbauer A, Colinge J, Kaupe I, Bilban M, Burkard T, et al. The chemokine interleukin-8 and the surface activation protein CD69 are markers for Bcr-Abl activity in chronic myeloid leukemia. Mol Oncol. 2008;2:272-81 pubmed publisher
  • flow cytometry; African green monkey; loading ...; tbl 2
Rodriguez A, Arulanandam B, Hodara V, McClure H, Cobb E, Salas M, et al. Influence of interleukin-15 on CD8+ natural killer cells in human immunodeficiency virus type 1-infected chimpanzees. J Gen Virol. 2007;88:641-51 pubmed publisher
  • flow cytometry; human; fig 1
Chen L, Cohen A, Lewis D. Impaired allogeneic activation and T-helper 1 differentiation of human cord blood naive CD4 T cells. Biol Blood Marrow Transplant. 2006;12:160-71 pubmed
  • flow cytometry; human
Koshiba M, Rosin D, Hayashi N, Linden J, Sitkovsky M. Patterns of A2A extracellular adenosine receptor expression in different functional subsets of human peripheral T cells. Flow cytometry studies with anti-A2A receptor monoclonal antibodies. Mol Pharmacol. 1999;55:614-24 pubmed
Jiang W, Adler L, Macmillan H, Mellins E. Synergy between B cell receptor/antigen uptake and MHCII peptide editing relies on HLA-DO tuning. Sci Rep. 2019;9:13877 pubmed publisher
de Oliveira A, Amadeu T, de França Gomes A, Menezes V, da Costa Nery J, Pinheiro R, et al. Role of CD8(+) T cells in triggering reversal reaction in HIV/leprosy patients. Immunology. 2013;140:47-60 pubmed publisher
Wang X, Xu H, Alvarez X, Pahar B, Moroney Rasmussen T, Lackner A, et al. Distinct expression patterns of CD69 in mucosal and systemic lymphoid tissues in primary SIV infection of rhesus macaques. PLoS ONE. 2011;6:e27207 pubmed publisher
product information
Product Type :
Antibody
Product Name :
CD69 Monoclonal Antibody (CH/4), PE
Catalog # :
MHCD6904
Quantity :
500 µL
Price :
US 386.00
Clonality :
Monoclonal
Purity :
purified
Host :
Mouse
Reactivity :
Human
Applications :
Flow Cytometry: Assay-Dependent
Species :
Human
Clone :
CH/4
Isotype :
IgG2a
Storage :
4° C, store in dark
Description :
CD69 (AIM, Active Inducer Molecule) is a gp28/34 disulfide bonded homodimer with a molecular weight of 60 kDa under non-reducing conditions. CD69 contains one or two N linked oligosacaride and the molecule is present on activated platelets. In normal peripheral blood a variable percentage of cells express the CD69 antigen, and it is involved in lymphocyte signal transduction. Expression CD69 is induced upon activation of T lymphocytes, and may play a role in proliferation. Furthermore, the protein may act to transmit signals in natural killer cells and platelets. Alternative splicing results in multiple transcript variants of CD69. Diseases associated with CD69 dysfunction include coccidiodomycosis and asthma.
Immunogen :
Human CD69
Format :
Liquid
Applications w/Dilutions :
Flow Cytometry: Assay-Dependent
Aliases :
5830438K24Rik; Activation inducer molecule; activation inducer molecule (AIM/CD69); AI452015; AIM; BL-AC/P26; CD69; CD69 antigen; CD69 antigen (p60, early T-cell activation antigen); CD69 molecule; CLEC2C; C-type lectin domain family 2 member C; C-type lectin domain family 2, member C; EA1; early activation antigen CD69; early lymphocyte activation antigen; early T-cell activation antigen p60; GP32/28; leukocyte surface antigen Leu-23; MLR-3; VEA; Very Early Activation Antigen
more info or order :
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA