This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
CD38 Monoclonal Antibody (HIT2), FITC
catalog :
MHCD3801-4
quantity :
2 mL
price :
US 1122.00
clonality :
monoclonal
host :
mouse
conjugate :
FITC
reactivity :
human
application :
flow cytometry
citations: 7
Reference
de Oliveira A, Amadeu T, de França Gomes A, Menezes V, da Costa Nery J, Pinheiro R, et al. Role of CD8(+) T cells in triggering reversal reaction in HIV/leprosy patients. Immunology. 2013;140:47-60 pubmed publisher
Zhang X, Dormady S, Basch R. Identification of four human cDNAs that are differentially expressed by early hematopoietic progenitors. Exp Hematol. 2000;28:1286-96 pubmed
Grammer A, McFarland R, Heaney J, Darnell B, Lipsky P. Expression, regulation, and function of B cell-expressed CD154 in germinal centers. J Immunol. 1999;163:4150-9 pubmed
Denning Kendall P, Horsley H, Donaldson C, Bradley B, Hows J. Different behaviour of fresh and cultured CD34+ cells during immunomagnetic separation. Br J Haematol. 1999;105:780-5 pubmed
Hryhorenko E, Rittenhouse Diakun K, Harvey N, Morgan J, Stewart C, Oseroff A. Characterization of endogenous protoporphyrin IX induced by delta-aminolevulinic acid in resting and activated peripheral blood lymphocytes by four-color flow cytometry. Photochem Photobiol. 1998;67:565-72 pubmed
van der Voort R, Taher T, Keehnen R, Smit L, Groenink M, Pals S. Paracrine regulation of germinal center B cell adhesion through the c-met-hepatocyte growth factor/scatter factor pathway. J Exp Med. 1997;185:2121-31 pubmed
Muench M, Roncarolo M, Menon S, Xu Y, Kastelein R, Zurawski S, et al. FLK-2/FLT-3 ligand regulates the growth of early myeloid progenitors isolated from human fetal liver. Blood. 1995;85:963-72 pubmed
product information
Product Type :
Antibody
Product Name :
CD38 Monoclonal Antibody (HIT2), FITC
Catalog # :
MHCD3801-4
Quantity :
2 mL
Price :
US 1122.00
Clonality :
Monoclonal
Purity :
purified
Host :
Mouse
Reactivity :
Human
Applications :
Flow Cytometry: Assay-Dependent
Species :
Human
Clone :
HIT2
Isotype :
IgG1
Storage :
4 C, store in dark
Description :
CD38 (NAD+ glycohydrolase) is a type II transmembrane glycoprotein able to induce activation, proliferation and differentiation of mature lymphocytes and mediate apoptosis of myeloid and lymphoid progenitor cells. CD38 functions as a multi-catalytic ectoenzyme serving as ADP-ribosyl cyclase, cyclic ADP-ribose hydrolase and possibly NAD+ glycohydrolase or as a cell surface receptor. Antibodies to CD38 are useful in subtyping of lymphomas and leukemias, detection of plasma cells (i.e. identification of myelomas), and as a marker for activated B and T cells. CD38 participates in cell adhesion, signal transduction and calcium signaling. Further, CD38 is expressed at high levels in the pancreas, liver, kidney, malignant lymphoma and neuroblastoma. Diseases associated with CD38 dysfunction include chronic lymphocytic leukemia and Richter's Syndrome.
Immunogen :
Human CD38
Format :
Liquid
Applications w/Dilutions :
Flow Cytometry: Assay-Dependent
Aliases :
2'-phospho-ADP-ribosyl cyclase; 2'-phospho-ADP-ribosyl cyclase/2'-phospho-cyclic-ADP-ribose transferase; 2'-phospho-cyclic-ADP-ribose transferase; ADPRC 1; ADPRC1; ADP-ribosyl cyclase 1; ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1; cADPr hydrolase 1; Cd38; CD38 antigen; CD38 antigen (ADP-ribosyl cyclase / cyclic ADP-ribose hydrolase); CD38 antigen (p45); CD38 antigen p45; CD38 molecule; CD38H; Cd38-rs1; cluster of differentiation 38; cyclic ADP-ribose hydrolase 1; ecto-nicotinamide adenine dinucleotide glycohydrolase; I-19; NAD(+) nucleosidase; NAD+ nucleosidase; NIM-R5 antigen; T10
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA