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company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
CD31 Monoclonal Antibody (MBC78.2), FITC
catalog :
MHCD3101
quantity :
500 uL
price :
US 356.00
clonality :
monoclonal
host :
mouse
conjugate :
FITC
clone name :
MBC78.2
reactivity :
human
application :
immunocytochemistry, flow cytometry
more info or order :
citations: 9
Published Application/Species/Sample/Dilution | Reference |
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| Ramirez R, Carracedo J, Merino A, Nogueras S, Alvarez Lara M, Rodriguez M, et al. Microinflammation induces endothelial damage in hemodialysis patients: the role of convective transport. Kidney Int. 2007;72:108-13 pubmed
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| Hristov M, Zernecke A, Bidzhekov K, Liehn E, Shagdarsuren E, Ludwig A, et al. Importance of CXC chemokine receptor 2 in the homing of human peripheral blood endothelial progenitor cells to sites of arterial injury. Circ Res. 2007;100:590-7 pubmed
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| Vallario A, Chilosi M, Adami F, Montagna L, Deaglio S, Malavasi F, et al. Human myeloma cells express the CD38 ligand CD31. Br J Haematol. 1999;105:441-4 pubmed
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Mitchell J, McIntosh K, Zvonic S, Garrett S, Floyd Z, Kloster A, et al. Immunophenotype of human adipose-derived cells: temporal changes in stromal-associated and stem cell-associated markers. Stem Cells. 2006;24:376-85 pubmed
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product information
Product Type :
Antibody
Product Name :
CD31 Monoclonal Antibody (MBC78.2), FITC
Catalog # :
MHCD3101
Quantity :
500 uL
Price :
US 356.00
Clonality :
Monoclonal
Purity :
purified
Host :
Mouse
Reactivity :
Human
Applications :
Flow Cytometry: Assay-Dependent
Species :
Human
Clone :
MBC78.2
Isotype :
IgG1
Storage :
4 C, store in dark
Description :
CD31 (platelet endothelial cell adhesion molecule-1, PECAM-1) is an inhibitory coreceptor involved in regulation of T cell and B cell signaling by a dual immunoreceptor tyrosine-based inhibitory motif (ITIM) that upon associated kinases-mediated phosphorylation provide docking sites for protein-tyrosine phosphatases. CD31 is expressed ubiquitously within the vascular compartment and is located mainly at junctions between adjacent cells. N-terminal Ig-like domain of CD31 is responsible for its homophilic binding, which plays an important role in cell-cell interactions. CD31 is a multifunctional molecule with diverse roles in modulation of integrin-mediated cell adhesion, transendothelial migration, angiogenesis, apoptosis, negative regulation of immunoreceptor signaling, autoimmunity, macrophage phagocytosis, IgE-mediated anaphylaxis and thrombosis. It is one of key regulatory molecules in vascular system.
Immunogen :
Human CD31
Format :
Liquid
Applications w/Dilutions :
Flow Cytometry: Assay-Dependent
Aliases :
C85791; CD31; CD31 antigen; CD31, PECAM-1; CD31/EndoCAM; endoCAM; GPIIA'; I79_008304; PECA1; Pecam; PECAM1; Pecam-1; platelet and endothelial cell adhesion molecule 1; platelet endothelial cell adhesion molecule; platelet endothelial cell adhesion molecule-1; platelet/endothelial cell adhesion molecule (CD31 antigen); platelet/endothelial cell adhesion molecule 1; type I transmembrane endothelial adhesion molecule
more info or order :
company information

Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com81 Wyman Street
Waltham, MA USA 02451
800-678-5599
headquarters: USA
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