product summary
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company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
CD19 Monoclonal Antibody (SJ25-C1), PerCP
catalog :
MHCD1931
quantity :
500 uL
price :
US 508.00
clonality :
monoclonal
host :
mouse
conjugate :
PerCP
clone name :
SJ25-C1
reactivity :
human
application :
flow cytometry
more info or order :
Invitrogen product webpage
citations: 2
Published Application/Species/Sample/DilutionReference
  • flow cytometry; human; fig 1
Arriaga Pizano L, Ferat Osorio E, Rodríguez Abrego G, Mancilla Herrera I, Domínguez Cerezo E, Valero Pacheco N, et al. Differential Immune Profiles in Two Pandemic Influenza A(H1N1)pdm09 Virus Waves at Pandemic Epicenter. Arch Med Res. 2015;46:651-8 pubmed publisher
Cérbulo Vázquez A, Figueroa Damián R, Arriaga Pizano L, Hernández Andrade E, Mancilla Herrera I, Flores Mejía L, et al. Pregnant women infected with pandemic H1N1pdm2009 influenza virus displayed overproduction of peripheral blood CD69+ lymphocytes and increased levels of serum cytokines. PLoS ONE. 2014;9:e107900 pubmed publisher
product information
Product Type :
Antibody
Product Name :
CD19 Monoclonal Antibody (SJ25-C1), PerCP
Catalog # :
MHCD1931
Quantity :
500 uL
Price :
US 508.00
Clonality :
Monoclonal
Purity :
Affinity chromatography
Host :
Mouse
Reactivity :
Human
Applications :
Flow Cytometry: Assay-Dependent
Species :
Human
Clone :
SJ25-C1
Isotype :
IgG1, kappa
Storage :
4 C, store in dark
Description :
CD19 is a member of the immunoglobulin superfamily and has two Ig like domains. The CD19 molecule is expressed on 100% of the peripheral B cells as defined by expression of kappa or lambda light chains. CD19 appears to be expressed on myeloid leukemia cells, particularly those of monocytic lineage. Leukemia phenotype studies have demonstrated that the earliest and broadest B cell restricted antigen is the CD19 antigen. The receptor for CD19 is an important functional regulator of normal and malignant B cell proliferation, and is expressed in all B cell precursor leukemias. Lymphocytes proliferate and differentiate in response to various concentrations of different antigens. The ability of the B cell to respond in a specific, yet sensitive manner to the various antigens is achieved with the use of low-affinity antigen receptors. CD19 is a cell surface molecule which assembles with the antigen receptor of B lymphocytes in order to decrease the threshold for antigen receptor-dependent stimulation. Besides being a signal-amplifying coreceptor for the B cell receptor (BCR), CD19 can also signal independently of BCR co-ligation and is a central regulatory component upon which multiple signaling pathways converge. Mutation of the CD19 gene results in hypogammaglobulinemia, whereas CD19 overexpression causes B cell hyperactivity.
Immunogen :
Nalm 1 Human cell line
Format :
Liquid
Applications w/Dilutions :
Flow Cytometry: Assay-Dependent
Aliases :
AW495831; B4; B-lymphocyte antigen CD19; B-lymphocyte surface antigen B4; Cd19; CD19 antigen; CD19 molecule; CVID3; differentiation antigen CD19; Leu-12; T-cell surface antigen Leu-12
more info or order :
Invitrogen product webpage
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA