CD19 Monoclonal Antibody (SJ25-C1), PE | Invitrogen MHCD1904 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CD19 Monoclonal Antibody (SJ25-C1), PE

catalog :

MHCD1904

quantity :

500 µL

price :

US 351

clonality :

monoclonal

host :

mouse

conjugate :

clone name :

SJ25-C1

reactivity :

human

application :

flow cytometry

more info or order :

Invitrogen product webpage

citations: 12

Published Application/Species/Sample/Dilution	Reference
flow cytometry; human; fig 1	Lee J, Breton G, Oliveira T, Zhou Y, Aljoufi A, PUHR S, et al. Restricted dendritic cell and monocyte progenitors in human cord blood and bone marrow. J Exp Med. 2015;212:385-99 pubmed publisher
flow cytometry; human; fig 1	Schmetterer K, Seidel M, Körmöczi U, Rottal A, Schwarz K, Matthes Martin S, et al. Two newly diagnosed HLA class II-deficient patients identified by rapid vector-based complementation analysis reveal discoordinate invariant chain expression levels. Int Arch Allergy Immunol. 2010;152:390-400 pubmed publisher
flow cytometry; human; fig 3	Erlendsson L, Muench M, Hellman U, Hrafnkelsdóttir S, Jonsson A, Balmer Y, et al. Barley as a green factory for the production of functional Flt3 ligand. Biotechnol J. 2010;5:163-71 pubmed publisher
flow cytometry; human; 1:20; fig 3	Strickland L, Ross J, Williams S, Ross S, Romero M, Spencer S, et al. Preclinical evaluation of carcinoembryonic cell adhesion molecule (CEACAM) 6 as potential therapy target for pancreatic adenocarcinoma. J Pathol. 2009;218:380-90 pubmed publisher
flow cytometry; human; tbl 1	del Giudice I, Matutes E, Morilla R, Morilla A, Owusu Ankomah K, Rafiq F, et al. The diagnostic value of CD123 in B-cell disorders with hairy or villous lymphocytes. Haematologica. 2004;89:303-8 pubmed
flow cytometry; human; tbl 1	Yokota T, Meka C, Kouro T, Medina K, Igarashi H, Takahashi M, et al. Adiponectin, a fat cell product, influences the earliest lymphocyte precursors in bone marrow cultures by activation of the cyclooxygenase-prostaglandin pathway in stromal cells. J Immunol. 2003;171:5091-9 pubmed
flow cytometry; human	Stacchini A, Demurtas A, Godio L, Martini G, Antinoro V, Palestro G. Flow cytometry in the bone marrow staging of mature B-cell neoplasms. Cytometry B Clin Cytom. 2003;54:10-8 pubmed
flow cytometry; human; 5 ug/ml	McIlroy D, Troadec C, Grassi F, Samri A, Barrou B, Autran B, et al. Investigation of human spleen dendritic cell phenotype and distribution reveals evidence of in vivo activation in a subset of organ donors. Blood. 2001;97:3470-7 pubmed
flow cytometry; human; fig 2	Nomdedeu J, Mateu R, Altes A, Llorente A, Rio C, Estivill C, et al. Enhanced myeloid specificity of CD117 compared with CD13 and CD33. Leuk Res. 1999;23:341-7 pubmed
	Xia X, Li H, Satheesan S, Zhou J, Rossi J. Humanized NOD/SCID/IL2rγnull (hu-NSG) Mouse Model for HIV Replication and Latency Studies. J Vis Exp. 2019;: pubmed publisher
	Timeus F, Crescenzio N, Sanavio F, Fazio L, Doria A, Foglia L, et al. Multilineage engraftment of refrozen cord blood hematopoietic progenitors in NOD/SCID mice. Haematologica. 2006;91:369-72 pubmed
	Prussin C, Griffith D, Boesel K, Lin H, Foster B, Casale T. Omalizumab treatment downregulates dendritic cell FcepsilonRI expression. J Allergy Clin Immunol. 2003;112:1147-54 pubmed

product information

Product Type :

Antibody

Product Name :

CD19 Monoclonal Antibody (SJ25-C1), PE

Catalog # :

MHCD1904

Quantity :

500 µL

Price :

US 351

Clonality :

Monoclonal

Purity :

purified

Host :

Mouse

Reactivity :

Human

Applications :

Flow Cytometry: Assay-Dependent

Species :

Human

Clone :

SJ25-C1

Isotype :

IgG1, kappa

Storage :

4° C, store in dark

Description :

CD19 is a member of the immunoglobulin superfamily and has two Ig like domains. The CD19 molecule is expressed on 100% of the peripheral B cells as defined by expression of kappa or lambda light chains. CD19 appears to be expressed on myeloid leukemia cells, particularly those of monocytic lineage. Leukemia phenotype studies have demonstrated that the earliest and broadest B cell restricted antigen is the CD19 antigen. The receptor for CD19 is an important functional regulator of normal and malignant B cell proliferation, and is expressed in all B cell precursor leukemias. Lymphocytes proliferate and differentiate in response to various concentrations of different antigens. The ability of the B cell to respond in a specific, yet sensitive manner to the various antigens is achieved with the use of low-affinity antigen receptors. CD19 is a cell surface molecule which assembles with the antigen receptor of B lymphocytes in order to decrease the threshold for antigen receptor-dependent stimulation. Besides being a signal-amplifying coreceptor for the B cell receptor (BCR), CD19 can also signal independently of BCR co-ligation and is a central regulatory component upon which multiple signaling pathways converge. Mutation of the CD19 gene results in hypogammaglobulinemia, whereas CD19 overexpression causes B cell hyperactivity.

Immunogen :

Nalm 1 Human cell line

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: Assay-Dependent

Aliases :

AW495831; B4; B-lymphocyte antigen CD19; B-lymphocyte surface antigen B4; Cd19; CD19 antigen; CD19 molecule; CVID3; differentiation antigen CD19; Leu-12; T-cell surface antigen Leu-12

more info or order :

Invitrogen product webpage