CD19 Monoclonal Antibody (SJ25-C1), FITC | Invitrogen MHCD1901 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CD19 Monoclonal Antibody (SJ25-C1), FITC

catalog :

MHCD1901

quantity :

500 uL

price :

US 348.00

clonality :

monoclonal

host :

mouse

conjugate :

FITC

clone name :

SJ25-C1

reactivity :

human

application :

flow cytometry

more info or order :

Invitrogen product webpage

citations: 11

Published Application/Species/Sample/Dilution	Reference
flow cytometry; human; 1:100; loading ...; fig S5a	Pyöriä L, Toppinen M, Mäntylä E, Hedman L, Aaltonen L, Vihinen Ranta M, et al. Extinct type of human parvovirus B19 persists in tonsillar B cells. Nat Commun. 2017;8:14930 pubmed publisher
flow cytometry; human; fig 2a	Oelsner S, Friede M, Zhang C, Wagner J, Badura S, Bader P, et al. Continuously expanding CAR NK-92 cells display selective cytotoxicity against B-cell leukemia and lymphoma. Cytotherapy. 2017;19:235-249 pubmed publisher
flow cytometry; human	Feng Y, Zhang N, Jacobs K, Jiang W, Yang L, Li Z, et al. Polarization imaging and classification of Jurkat T and Ramos B cells using a flow cytometer. Cytometry A. 2014;85:817-26 pubmed publisher
flow cytometry; human	Giannelli S, Taddeo A, Presicce P, Villa M, Della Bella S. A six-color flow cytometric assay for the analysis of peripheral blood dendritic cells. Cytometry B Clin Cytom. 2008;74:349-55 pubmed publisher
flow cytometry; human	Diaz Blanco E, Bruns I, Neumann F, Fischer J, Graef T, Rosskopf M, et al. Molecular signature of CD34(+) hematopoietic stem and progenitor cells of patients with CML in chronic phase. Leukemia. 2007;21:494-504 pubmed
flow cytometry; human	Campbell R, Manyak S, Yang H, Sjak Shie N, Chen H, Gui D, et al. LAGlambda-1: a clinically relevant drug resistant human multiple myeloma tumor murine model that enables rapid evaluation of treatments for multiple myeloma. Int J Oncol. 2006;28:1409-17 pubmed
flow cytometry; human; tbl 1	del Giudice I, Matutes E, Morilla R, Morilla A, Owusu Ankomah K, Rafiq F, et al. The diagnostic value of CD123 in B-cell disorders with hairy or villous lymphocytes. Haematologica. 2004;89:303-8 pubmed
flow cytometry; human; fig 2	Sharron M, Pohlmann S, Price K, Lolis E, Tsang M, Kirchhoff F, et al. Expression and coreceptor activity of STRL33/Bonzo on primary peripheral blood lymphocytes. Blood. 2000;96:41-9 pubmed
flow cytometry; human; fig 1	Eksioglu Demiralp E, Budak Alpdogan T, Alpdogan O, Atalay A, Ratip S, Oz D, et al. Double G0/G1 peak in the DNA histogram of aberrant marker positive acute leukemia patients is associated with a poor clinical outcome. Leuk Lymphoma. 1999;33:567-72 pubmed
	Rafiq S, YEKU O, Jackson H, Purdon T, van Leeuwen D, Drakes D, et al. Targeted delivery of a PD-1-blocking scFv by CAR-T cells enhances anti-tumor efficacy in vivo. Nat Biotechnol. 2018;36:847-856 pubmed publisher
	Zhao R, Follows G, Beer P, Scott L, Huntly B, Green A, et al. Inhibition of the Bcl-xL deamidation pathway in myeloproliferative disorders. N Engl J Med. 2008;359:2778-89 pubmed publisher

product information

Product Type :

Antibody

Product Name :

CD19 Monoclonal Antibody (SJ25-C1), FITC

Catalog # :

MHCD1901

Quantity :

500 uL

Price :

US 348.00

Clonality :

Monoclonal

Purity :

purified

Host :

Mouse

Reactivity :

Human

Applications :

Flow Cytometry: Assay-Dependent

Species :

Human

Clone :

SJ25-C1

Isotype :

IgG1, kappa

Storage :

4 C, store in dark

Description :

CD19 is a member of the immunoglobulin superfamily and has two Ig like domains. The CD19 molecule is expressed on 100% of the peripheral B cells as defined by expression of kappa or lambda light chains. CD19 appears to be expressed on myeloid leukemia cells, particularly those of monocytic lineage. Leukemia phenotype studies have demonstrated that the earliest and broadest B cell restricted antigen is the CD19 antigen. The receptor for CD19 is an important functional regulator of normal and malignant B cell proliferation, and is expressed in all B cell precursor leukemias. Lymphocytes proliferate and differentiate in response to various concentrations of different antigens. The ability of the B cell to respond in a specific, yet sensitive manner to the various antigens is achieved with the use of low-affinity antigen receptors. CD19 is a cell surface molecule which assembles with the antigen receptor of B lymphocytes in order to decrease the threshold for antigen receptor-dependent stimulation. Besides being a signal-amplifying coreceptor for the B cell receptor (BCR), CD19 can also signal independently of BCR co-ligation and is a central regulatory component upon which multiple signaling pathways converge. Mutation of the CD19 gene results in hypogammaglobulinemia, whereas CD19 overexpression causes B cell hyperactivity.

Immunogen :

Nalm 1 Human cell line

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: Assay-Dependent

Aliases :

AW495831; B4; B-lymphocyte antigen CD19; B-lymphocyte surface antigen B4; Cd19; CD19 antigen; CD19 molecule; CVID3; differentiation antigen CD19; Leu-12; T-cell surface antigen Leu-12

more info or order :

Invitrogen product webpage