CD16 Monoclonal Antibody (3G8), PE | Invitrogen MHCD1604-4 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CD16 Monoclonal Antibody (3G8), PE

catalog :

MHCD1604-4

quantity :

2 ml

price :

US 910.00

clonality :

monoclonal

host :

mouse

conjugate :

clone name :

3G8

reactivity :

human

application :

flow cytometry

citations: 6

Reference
Chauhan A, Chen C, Moore T, DiPaolo R. Induced expression of FcÎ³RIIIa (CD16a) on CD4+ T cells triggers generation of IFN-Î³high subset. J Biol Chem. 2015;290:5127-40 pubmed publisher
Schmidt J, Bell F, Akam E, Marshall C, Dainty I, Heinemann A, et al. Biochemical and pharmacological characterization of AZD1981, an orally available selective DP2 antagonist in clinical development for asthma. Br J Pharmacol. 2013;168:1626-38 pubmed publisher
Herzmann C, Ernst M, Ehlers S, Stenger S, Maertzdorf J, Sotgiu G, et al. Increased frequencies of pulmonary regulatory T-cells in latent Mycobacterium tuberculosis infection. Eur Respir J. 2012;40:1450-7 pubmed publisher
Choi K, Vodyanik M, Slukvin I. Hematopoietic differentiation and production of mature myeloid cells from human pluripotent stem cells. Nat Protoc. 2011;6:296-313 pubmed publisher
McIlroy D, Troadec C, Grassi F, Samri A, Barrou B, Autran B, et al. Investigation of human spleen dendritic cell phenotype and distribution reveals evidence of in vivo activation in a subset of organ donors. Blood. 2001;97:3470-7 pubmed
Gopinath R, Hanna L, Kumaraswami V, Perumal V, Kavitha V, Vijayasekaran V, et al. Perturbations in eosinophil homeostasis following treatment of lymphatic filariasis. Infect Immun. 2000;68:93-9 pubmed

product information

Product Type :

Antibody

Product Name :

CD16 Monoclonal Antibody (3G8), PE

Catalog # :

MHCD1604-4

Quantity :

2 ml

Price :

US 910.00

Clonality :

Monoclonal

Purity :

purified

Host :

Mouse

Reactivity :

Human

Applications :

Flow Cytometry: Assay-Dependent

Species :

Human

Clone :

3G8

Isotype :

IgG1, kappa

Storage :

4° C, store in dark

Description :

CD16 (FCGR3A) is a 50-65 kDa cell surface molecule that exists in two forms - a transmembranous form expressed by NK cells and some T cells, and a phosphatidylinositol linked form expressed by granulocytes. CD16 is a low affinity receptor for IgG (FcR III), and is an important receptor mediating ADCC by NK cells. Human CD16 is expressed in two forms – FCGR3A and FCGR3B. FCGR3A is associated with the FcepsilonRI-gamma subunit and is responsible for antibody-dependent NK cell cytotoxicity. Mast cell FCGR3A is associated, with FcepsilonRI-beta subunit. Besides IgG, FCGR3A can be triggered also by oligomeric IgE. FCGR3B is a GPI-linked monomeric receptor expressed on neutrophils and is involved in their activation and induction of a pro-adhesive phenotype. Diseases associated with CD16 dysfunction include immunodeficiency 20 and systemic lupus erythematosus.

Immunogen :

Human CD16

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: Assay-Dependent

Aliases :

FCGR3A, FCGR3B, CD16A, CD16B, Fc gamma Receptor III, Fc gamma Receptor 3, RP11-5K23.1, FCGR3, FCGRIII, FCR-10, FCRIII, FCRIIIA