CD14 Monoclonal Antibody (TuK4), Pacific Blue | Invitrogen MHCD1428 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CD14 Monoclonal Antibody (TuK4), Pacific Blue

catalog :

MHCD1428

quantity :

500 uL

price :

US 544.00

clonality :

monoclonal

host :

mouse

conjugate :

Pacific Blue

clone name :

TUK4

reactivity :

human

application :

immunocytochemistry, flow cytometry

more info or order :

Invitrogen product webpage

citations: 22

Published Application/Species/Sample/Dilution	Reference
flow cytometry; human; loading ...; fig s2c	Banki Z, Krabbendam L, Klaver D, Leng T, Kruis S, Mehta H, et al. Antibody opsonization enhances MAIT cell responsiveness to bacteria via a TNF-dependent mechanism. Immunol Cell Biol. 2019;97:538-551 pubmed publisher
flow cytometry; human; 5 ul	Hoffmann J, Shmeleva E, Boag S, Fiser K, Bagnall A, Murali S, et al. Myocardial ischemia and reperfusion leads to transient CD8 immune deficiency and accelerated immunosenescence in CMV-seropositive patients. Circ Res. 2015;116:87-98 pubmed publisher
flow cytometry; human immunocytochemistry; human	Bennaceur K, Atwill M, Al Zhrany N, Hoffmann J, Keavney B, BREAULT D, et al. Atorvastatin induces T cell proliferation by a telomerase reverse transcriptase (TERT) mediated mechanism. Atherosclerosis. 2014;236:312-20 pubmed publisher
flow cytometry; human	Ilander M, Kreutzman A, Rohon P, Melo T, Faber E, Porkka K, et al. Enlarged memory T-cell pool and enhanced Th1-type responses in chronic myeloid leukemia patients who have successfully discontinued IFN-? monotherapy. PLoS ONE. 2014;9:e87794 pubmed publisher
flow cytometry; human; fig 9	Pala P, Serwanga J, Watera C, Ritchie A, Moodie Z, Wang M, et al. Quantitative and qualitative differences in the T cell response to HIV in uninfected Ugandans exposed or unexposed to HIV-infected partners. J Virol. 2013;87:9053-63 pubmed publisher
flow cytometry; human	McArthur M, Sztein M. Heterogeneity of multifunctional IL-17A producing S. Typhi-specific CD8+ T cells in volunteers following Ty21a typhoid immunization. PLoS ONE. 2012;7:e38408 pubmed publisher
flow cytometry; human	Phadwal K, Alegre Abarrategui J, Watson A, Pike L, Anbalagan S, Hammond E, et al. A novel method for autophagy detection in primary cells: impaired levels of macroautophagy in immunosenescent T cells. Autophagy. 2012;8:677-89 pubmed publisher
flow cytometry; human; fig 4	Clement M, Ladell K, Ekeruche Makinde J, Miles J, Edwards E, Dolton G, et al. Anti-CD8 antibodies can trigger CD8+ T cell effector function in the absence of TCR engagement and improve peptide-MHCI tetramer staining. J Immunol. 2011;187:654-63 pubmed publisher
	Huuhtanen J, Ilander M, Yadav B, Dufva O, L xe4 hteenm xe4 ki H, Kasanen T, et al. IFN-α with dasatinib broadens the immune repertoire in patients with chronic-phase chronic myeloid leukemia. J Clin Invest. 2022;132: pubmed publisher
	Keeton R, Richardson S, Moyo Gwete T, Hermanus T, Tincho M, Benede N, et al. Prior infection with SARS-CoV-2 boosts and broadens Ad26.COV2.S immunogenicity in a variant-dependent manner. Cell Host Microbe. 2021;29:1611-1619.e5 pubmed publisher
	Rahmani N, Ramachandra N, Sahu S, Gitego N, Lopez A, Pradhan K, et al. ASXL1 mutations are associated with distinct epigenomic alterations that lead to sensitivity to venetoclax and azacytidine. Blood Cancer J. 2021;11:157 pubmed publisher
	Arif S, Gomez Tourino I, Kamra Y, Pujol Autonell I, Hanton E, Tree T, et al. GAD-alum immunotherapy in type 1 diabetes expands bifunctional Th1/Th2 autoreactive CD4 T cells. Diabetologia. 2020;63:1186-1198 pubmed publisher
	Hataye J, Casazza J, Best K, Liang C, Immonen T, Ambrozak D, et al. Principles Governing Establishment versus Collapse of HIV-1 Cellular Spread. Cell Host Microbe. 2019;26:748-763.e20 pubmed publisher
	Yabe I, Truitt L, Espinoza D, Wu C, Koelle S, Panch S, et al. Barcoding of Macaque Hematopoietic Stem and Progenitor Cells: A Robust Platform to Assess Vector Genotoxicity. Mol Ther Methods Clin Dev. 2018;11:143-154 pubmed publisher
	Jain P, Tian X, Cordes S, Chen J, Cantilena C, Bradley C, et al. Over-expression of PD-1 Does Not Predict Leukemic Relapse after Allogeneic Stem Cell Transplantation. Biol Blood Marrow Transplant. 2019;25:216-222 pubmed publisher
	Bartlett D, Willis L, Slentz C, Hoselton A, KELLY L, Huebner J, et al. Ten weeks of high-intensity interval walk training is associated with reduced disease activity and improved innate immune function in older adults with rheumatoid arthritis: a pilot study. Arthritis Res Ther. 2018;20:127 pubmed publisher
	Kim M, Yu K, Kenderian S, Ruella M, Chen S, Shin T, et al. Genetic Inactivation of CD33 in Hematopoietic Stem Cells to Enable CAR T Cell Immunotherapy for Acute Myeloid Leukemia. Cell. 2018;173:1439-1453.e19 pubmed publisher
	Gomez Tourino I, Kamra Y, Baptista R, Lorenc A, Peakman M. T cell receptor ?-chains display abnormal shortening and repertoire sharing in type 1 diabetes. Nat Commun. 2017;8:1792 pubmed publisher
	Tanko R, Soares A, Müller T, Garrett N, Samsunder N, Abdool Karim Q, et al. Effect of Antiretroviral Therapy on the Memory and Activation Profiles of B Cells in HIV-Infected African Women. J Immunol. 2017;198:1220-1228 pubmed publisher
	Wahid R, Fresnay S, Levine M, Sztein M. Immunization with Ty21a live oral typhoid vaccine elicits crossreactive multifunctional CD8+ T-cell responses against Salmonella enterica serovar Typhi, S. Paratyphi A, and S. Paratyphi B in humans. Mucosal Immunol. 2015;8:1349-59 pubmed publisher
	McArthur M, Sztein M. Unexpected heterogeneity of multifunctional T cells in response to superantigen stimulation in humans. Clin Immunol. 2013;146:140-52 pubmed publisher
	Aurelius J, Thorén F, Akhiani A, Brune M, Palmqvist L, Hansson M, et al. Monocytic AML cells inactivate antileukemic lymphocytes: role of NADPH oxidase/gp91(phox) expression and the PARP-1/PAR pathway of apoptosis. Blood. 2012;119:5832-7 pubmed publisher

product information

Product Type :

Antibody

Product Name :

CD14 Monoclonal Antibody (TuK4), Pacific Blue

Catalog # :

MHCD1428

Quantity :

500 uL

Price :

US 544.00

Clonality :

Monoclonal

Purity :

purified

Host :

Mouse

Reactivity :

Human

Applications :

Flow Cytometry: Assay-Dependent

Species :

Human

Clone :

TuK4

Isotype :

IgG2a

Storage :

4 C, store in dark

Description :

CD14 is a 55 kDa GPI-anchored glycoprotein that is constitutively expressed on the surface of mature monocytes, macrophages, and neutrophils. CD14 also serves as a multifunctional lipopolysaccharide receptor, and is released to the serum both as a secreted and enzymatically cleaved GPI-anchored form. CD14 binds lipopolysaccharide molecule in a reaction catalyzed by lipopolysaccharide-binding protein (LBP), an acute phase serum protein. The soluble sCD14 can discriminate slight structural differences between lipopolysaccharides and is important for neutralization of serum allochthonous lipopolysaccharides by reconstituted lipoprotein particles. Further, CD14 has been shown to bind apoptotic cells, and can affect allergic, inflammatory and infectious processes. Alternative splicing results in multiple transcript variants encoding the same CD14 isoform. Diseases associated with CD14 dysfunction include mycobacterium chelonae infection and Croup.

Immunogen :

Human CD14

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: Assay-Dependent

Aliases :

CD 14; CD14; CD14 antigen; CD14 molecule; cd14 monocyte; lipopolysaccharide receptor; lipoprotein receptor; LPSR antibody; monocyte differentiation antigen CD14; Monocyte differentiation antigen CD14, membrane-bound form; Monocyte differentiation antigen CD14, urinary form; monocyte differentiation antigen CD14; LOW QUALITY PROTEIN: monocyte differentiation antigen CD14; myeloid cell-specific leucine-rich glycoprotein; myeloid membrane glycoprotein precursor; sCD14; soluble CD14

more info or order :

Invitrogen product webpage