CD14 Monoclonal Antibody (TuK4), PE-Cyanine5.5 | Invitrogen MHCD1418 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CD14 Monoclonal Antibody (TuK4), PE-Cyanine5.5

catalog :

MHCD1418

quantity :

500 uL

price :

US 502.00

clonality :

monoclonal

host :

mouse

conjugate :

PE-Cy5.5

clone name :

TUK4

reactivity :

human

application :

flow cytometry

more info or order :

Invitrogen product webpage

citations: 7

Published Application/Species/Sample/Dilution	Reference
flow cytometry; human; fig 4	Anandasabapathy N, Breton G, Hurley A, Caskey M, Trumpfheller C, Sarma P, et al. Efficacy and safety of CDX-301, recombinant human Flt3L, at expanding dendritic cells and hematopoietic stem cells in healthy human volunteers. Bone Marrow Transplant. 2015;50:924-30 pubmed publisher
	Herati R, Knorr D, Vella L, Silva L, Chilukuri L, Apostolidis S, et al. PD-1 directed immunotherapy alters Tfh and humoral immune responses to seasonal influenza vaccine. Nat Immunol. 2022;23:1183-1192 pubmed publisher
	Seyres D, Cabassi A, Lambourne J, Burden F, Farrow S, McKinney H, et al. Transcriptional, epigenetic and metabolic signatures in cardiometabolic syndrome defined by extreme phenotypes. Clin Epigenetics. 2022;14:39 pubmed publisher
	Pasciuto E, Burton O, Roca C, Lagou V, Rajan W, Theys T, et al. Microglia Require CD4 T Cells to Complete the Fetal-to-Adult Transition. Cell. 2020;182:625-640.e24 pubmed publisher
	Callahan C, Apostolova L, Gao S, Risacher S, Case J, Saykin A, et al. Novel Markers of Angiogenesis in the Setting of Cognitive Impairment and Dementia. J Alzheimers Dis. 2020;75:959-969 pubmed publisher
	Garimalla S, Nguyen D, Halliley J, Tipton C, Rosenberg A, Fucile C, et al. Differential transcriptome and development of human peripheral plasma cell subsets. JCI Insight. 2019;4: pubmed publisher
	Belli A, Reis R, Veronese A, Moreira R, Flanagan K, Driver J, et al. Effects of treatment of preweaning dairy calves with recombinant bovine somatotropin on immune responses and somatotropic axis. J Dairy Sci. 2018;101:6602-6615 pubmed publisher

product information

Product Type :

Antibody

Product Name :

CD14 Monoclonal Antibody (TuK4), PE-Cyanine5.5

Catalog # :

MHCD1418

Quantity :

500 uL

Price :

US 502.00

Clonality :

Monoclonal

Purity :

purified

Host :

Mouse

Reactivity :

Human

Applications :

Flow Cytometry: Assay-Dependent

Species :

Human

Clone :

TuK4

Isotype :

IgG2a

Storage :

4 C, store in dark

Description :

CD14 is a 55 kDa GPI-anchored glycoprotein that is constitutively expressed on the surface of mature monocytes, macrophages, and neutrophils. CD14 also serves as a multifunctional lipopolysaccharide receptor, and is released to the serum both as a secreted and enzymatically cleaved GPI-anchored form. CD14 binds lipopolysaccharide molecule in a reaction catalyzed by lipopolysaccharide-binding protein (LBP), an acute phase serum protein. The soluble sCD14 can discriminate slight structural differences between lipopolysaccharides and is important for neutralization of serum allochthonous lipopolysaccharides by reconstituted lipoprotein particles. Further, CD14 has been shown to bind apoptotic cells, and can affect allergic, inflammatory and infectious processes. Alternative splicing results in multiple transcript variants encoding the same CD14 isoform. Diseases associated with CD14 dysfunction include mycobacterium chelonae infection and Croup.

Immunogen :

Human CD14

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: Assay-Dependent

Aliases :

CD 14; CD14; CD14 antigen; CD14 molecule; cd14 monocyte; lipopolysaccharide receptor; lipoprotein receptor; LPSR antibody; monocyte differentiation antigen CD14; Monocyte differentiation antigen CD14, membrane-bound form; Monocyte differentiation antigen CD14, urinary form; monocyte differentiation antigen CD14; LOW QUALITY PROTEIN: monocyte differentiation antigen CD14; myeloid cell-specific leucine-rich glycoprotein; myeloid membrane glycoprotein precursor; sCD14; soluble CD14

more info or order :

Invitrogen product webpage