This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
CD14 Monoclonal Antibody (TuK4), PE
catalog :
MHCD1404-4
quantity :
2 mL
price :
US 1276.00
clonality :
monoclonal
host :
mouse
conjugate :
PE
reactivity :
human
application :
flow cytometry
citations: 9
Reference
Lim C, Lee B, Geiger O, Passegger C, Beitzinger M, Romberger J, et al. miR-181a Modulation of ERK-MAPK Signaling Sustains DC-SIGN Expression and Limits Activation of Monocyte-Derived Dendritic Cells. Cell Rep. 2020;30:3793-3805.e5 pubmed publisher
Cucarián J, Berrío J, Rodrigues C, Zancan M, Wink M, de Oliveira A. Physical exercise and human adipose-derived mesenchymal stem cells ameliorate motor disturbances in a male rat model of Parkinson's disease. J Neurosci Res. 2019;97:1095-1109 pubmed publisher
Weiskopf K, Anderson K, Ito D, Schnorr P, Tomiyasu H, Ring A, et al. Eradication of Canine Diffuse Large B-Cell Lymphoma in a Murine Xenograft Model with CD47 Blockade and Anti-CD20. Cancer Immunol Res. 2016;4:1072-1087 pubmed
Onzi G, Ledur P, Hainzenreder L, Bertoni A, Silva A, Lenz G, et al. Analysis of the safety of mesenchymal stromal cells secretome for glioblastoma treatment. Cytotherapy. 2016;18:828-37 pubmed publisher
Bacchetta J, Chun R, Gales B, Zaritsky J, Leroy S, Wesseling Perry K, et al. Antibacterial responses by peritoneal macrophages are enhanced following vitamin D supplementation. PLoS ONE. 2014;9:e116530 pubmed publisher
Fomin M, Tai L, Barcena A, Muench M. Coexpression of CD14 and CD326 discriminate hepatic precursors in the human fetal liver. Stem Cells Dev. 2011;20:1247-57 pubmed publisher
Elsner L, Flügge P, Lozano J, Muppala V, Eiz Vesper B, Demiroglu S, et al. The endogenous danger signals HSP70 and MICA cooperate in the activation of cytotoxic effector functions of NK cells. J Cell Mol Med. 2010;14:992-1002 pubmed publisher
Strickland L, Ross J, Williams S, Ross S, Romero M, Spencer S, et al. Preclinical evaluation of carcinoembryonic cell adhesion molecule (CEACAM) 6 as potential therapy target for pancreatic adenocarcinoma. J Pathol. 2009;218:380-90 pubmed publisher
Canonico B, Zamai L, Burattini S, Granger V, Mannello F, Gobbi P, et al. Evaluation of leukocyte stabilisation in TransFix-treated blood samples by flow cytometry and transmission electron microscopy. J Immunol Methods. 2004;295:67-78 pubmed
product information
Product Type :
Antibody
Product Name :
CD14 Monoclonal Antibody (TuK4), PE
Catalog # :
MHCD1404-4
Quantity :
2 mL
Price :
US 1276.00
Clonality :
Monoclonal
Purity :
purified
Host :
Mouse
Reactivity :
Human
Applications :
Flow Cytometry: Assay-Dependent
Species :
Human
Clone :
TuK4
Isotype :
IgG2a
Storage :
4 C, store in dark
Description :
CD14 is a 55 kDa GPI-anchored glycoprotein that is constitutively expressed on the surface of mature monocytes, macrophages, and neutrophils. CD14 also serves as a multifunctional lipopolysaccharide receptor, and is released to the serum both as a secreted and enzymatically cleaved GPI-anchored form. CD14 binds lipopolysaccharide molecule in a reaction catalyzed by lipopolysaccharide-binding protein (LBP), an acute phase serum protein. The soluble sCD14 can discriminate slight structural differences between lipopolysaccharides and is important for neutralization of serum allochthonous lipopolysaccharides by reconstituted lipoprotein particles. Further, CD14 has been shown to bind apoptotic cells, and can affect allergic, inflammatory and infectious processes. Alternative splicing results in multiple transcript variants encoding the same CD14 isoform. Diseases associated with CD14 dysfunction include mycobacterium chelonae infection and Croup.
Immunogen :
Human CD14
Format :
Liquid
Applications w/Dilutions :
Flow Cytometry: Assay-Dependent
Aliases :
CD 14; CD14; CD14 antigen; CD14 molecule; cd14 monocyte; lipopolysaccharide receptor; lipoprotein receptor; LPSR antibody; monocyte differentiation antigen CD14; Monocyte differentiation antigen CD14, membrane-bound form; Monocyte differentiation antigen CD14, urinary form; monocyte differentiation antigen CD14; LOW QUALITY PROTEIN: monocyte differentiation antigen CD14; myeloid cell-specific leucine-rich glycoprotein; myeloid membrane glycoprotein precursor; sCD14; soluble CD14
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA