CD14 Monoclonal Antibody (TuK4), FITC | Invitrogen MHCD1401 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CD14 Monoclonal Antibody (TuK4), FITC

catalog :

MHCD1401

quantity :

500 uL

price :

US 359.00

clonality :

monoclonal

host :

mouse

conjugate :

FITC

clone name :

TUK4

reactivity :

human, rhesus macaque

application :

immunocytochemistry, flow cytometry

more info or order :

Invitrogen product webpage

citations: 16

Published Application/Species/Sample/Dilution	Reference
flow cytometry; human; 1:100; loading ...; fig s1d, s2a	Cassetta L, Fragkogianni S, Sims A, Swierczak A, Forrester L, Zhang H, et al. Human Tumor-Associated Macrophage and Monocyte Transcriptional Landscapes Reveal Cancer-Specific Reprogramming, Biomarkers, and Therapeutic Targets. Cancer Cell. 2019;35:588-602.e10 pubmed publisher
flow cytometry; human; 1:100; loading ...; fig 1	Herten M, Zilkens C, Thorey F, Tassemeier T, Lensing Höhn S, Fischer J, et al. Biomechanical Stability and Osteogenesis in a Tibial Bone Defect Treated by Autologous Ovine Cord Blood Cells-A Pilot Study. Molecules. 2019;24: pubmed publisher
immunocytochemistry; human	Mrosewski I, Jork N, Gorte K, Conrad C, Wiegand E, Kohl B, et al. Regulation of osteoarthritis-associated key mediators by TNF? and IL-10: effects of IL-10 overexpression in human synovial fibroblasts and a synovial cell line. Cell Tissue Res. 2014;357:207-23 pubmed publisher
flow cytometry; human	Blomkalns A, Gavrila D, Thomas M, Neltner B, Blanco V, Benjamin S, et al. CD14 directs adventitial macrophage precursor recruitment: role in early abdominal aortic aneurysm formation. J Am Heart Assoc. 2013;2:e000065 pubmed publisher
flow cytometry; human; 1:20; tbl 1	Chui K, Trivedi A, Cheng C, Cherbavaz D, Dazin P, Huynh A, et al. Characterization and functionality of proliferative human Sertoli cells. Cell Transplant. 2011;20:619-35 pubmed publisher
flow cytometry; human	Asin S, Fanger M, Wildt Perinic D, Ware P, Wira C, Howell A. Transmission of HIV-1 by primary human uterine epithelial cells and stromal fibroblasts. J Infect Dis. 2004;190:236-45 pubmed
flow cytometry; human	Stacchini A, Demurtas A, Godio L, Martini G, Antinoro V, Palestro G. Flow cytometry in the bone marrow staging of mature B-cell neoplasms. Cytometry B Clin Cytom. 2003;54:10-8 pubmed
flow cytometry; human; fig 4	Hertel L, Lacaille V, Strobl H, Mellins E, Mocarski E. Susceptibility of immature and mature Langerhans cell-type dendritic cells to infection and immunomodulation by human cytomegalovirus. J Virol. 2003;77:7563-74 pubmed
flow cytometry; human	Hajishengallis G, Martin M, Sojar H, Sharma A, Schifferle R, DeNardin E, et al. Dependence of bacterial protein adhesins on toll-like receptors for proinflammatory cytokine induction. Clin Diagn Lab Immunol. 2002;9:403-11 pubmed
flow cytometry; rhesus macaque	Giavedoni L, Velasquillo M, Parodi L, Hubbard G, Hodara V. Cytokine expression, natural killer cell activation, and phenotypic changes in lymphoid cells from rhesus macaques during acute infection with pathogenic simian immunodeficiency virus. J Virol. 2000;74:1648-57 pubmed
	Park T, Hirday R, Quinn R, Jacob S, Feldman R, Bose D, et al. Differentiation of monocytes and polarized M1/M2 macrophages from human induced pluripotent stem cells. STAR Protoc. 2024;5:102827 pubmed publisher
	Wang W, Pan D, Fu W, Ye X, Han J, Yang L, et al. Development of a skin- and neuro-attenuated live vaccine for varicella. Nat Commun. 2022;13:824 pubmed publisher
	Gong B, Zheng L, Lu Z, Huang J, Pu J, Pan S, et al. Mesenchymal stem cells negatively regulate CD4<sup>+</sup> T cell activation in patients with primary Sjögren syndrome through the miRNA‑125b and miRNA‑155 TCR pathway. Mol Med Rep. 2021;23: pubmed publisher
	Batta G, Soltész L, Kovacs T, Bozó T, Mészár Z, Kellermayer M, et al. Alterations in the properties of the cell membrane due to glycosphingolipid accumulation in a model of Gaucher disease. Sci Rep. 2018;8:157 pubmed publisher
	Hu Y, Yoshida K, Cologne J, Maki M, Morishita Y, Sasaki K, et al. CD14 and IL18 gene polymorphisms associated with colorectal cancer subsite risks among atomic bomb survivors. Hum Genome Var. 2015;2:15035 pubmed publisher
	Slobedman B, Mocarski E, Arvin A, Mellins E, Abendroth A. Latent cytomegalovirus down-regulates major histocompatibility complex class II expression on myeloid progenitors. Blood. 2002;100:2867-73 pubmed

product information

Product Type :

Antibody

Product Name :

CD14 Monoclonal Antibody (TuK4), FITC

Catalog # :

MHCD1401

Quantity :

500 uL

Price :

US 359.00

Clonality :

Monoclonal

Purity :

purified

Host :

Mouse

Reactivity :

Human

Applications :

Flow Cytometry: Assay-Dependent

Species :

Human

Clone :

TuK4

Isotype :

IgG2a

Storage :

4 C, store in dark

Description :

CD14 is a 55 kDa GPI-anchored glycoprotein that is constitutively expressed on the surface of mature monocytes, macrophages, and neutrophils. CD14 also serves as a multifunctional lipopolysaccharide receptor, and is released to the serum both as a secreted and enzymatically cleaved GPI-anchored form. CD14 binds lipopolysaccharide molecule in a reaction catalyzed by lipopolysaccharide-binding protein (LBP), an acute phase serum protein. The soluble sCD14 can discriminate slight structural differences between lipopolysaccharides and is important for neutralization of serum allochthonous lipopolysaccharides by reconstituted lipoprotein particles. Further, CD14 has been shown to bind apoptotic cells, and can affect allergic, inflammatory and infectious processes. Alternative splicing results in multiple transcript variants encoding the same CD14 isoform. Diseases associated with CD14 dysfunction include mycobacterium chelonae infection and Croup.

Immunogen :

Human CD14

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: Assay-Dependent

Aliases :

CD 14; CD14; CD14 antigen; CD14 molecule; cd14 monocyte; lipopolysaccharide receptor; lipoprotein receptor; LPSR antibody; monocyte differentiation antigen CD14; Monocyte differentiation antigen CD14, membrane-bound form; Monocyte differentiation antigen CD14, urinary form; monocyte differentiation antigen CD14; LOW QUALITY PROTEIN: monocyte differentiation antigen CD14; myeloid cell-specific leucine-rich glycoprotein; myeloid membrane glycoprotein precursor; sCD14; soluble CD14

more info or order :

Invitrogen product webpage