CD103 Monoclonal Antibody (LF61), PE | Invitrogen MHCD10304 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CD103 Monoclonal Antibody (LF61), PE

catalog :

MHCD10304

quantity :

500 uL

price :

US 422.00

clonality :

monoclonal

host :

mouse

conjugate :

clone name :

LF61

The same clone is also sold as:

OriGene: SM1800P, SM1800F, SM1800FT, SM1800R, SM1800PS
Bio-Rad: MCA1416SBV570, MCA1416SBV515, MCA1416SBUV740, MCA1416SBUV665, MCA1416SBB700, MCA1416SBUV795, MCA1416F, MCA1416FT, MCA1416SBV610, MCA1416SBUV510, MCA1416SBV760, MCA1416GA, MCA1416G, MCA1416PE, MCA1416SBV670, MCA1416SBV475, MCA1416SBUV400, MCA1416SBV710, MCA1416SBUV575, MCA1416SBV790, MCA1416SBV440, MCA1416SBUV445, MCA1416SBUV605

reactivity :

human

application :

flow cytometry

product information

Product Type :

Antibody

Product Name :

CD103 Monoclonal Antibody (LF61), PE

Catalog # :

MHCD10304

Quantity :

500 uL

Price :

US 422.00

Clonality :

Monoclonal

Purity :

purified

Host :

Mouse

Reactivity :

Human

Applications :

Flow Cytometry: Assay-Dependent

Species :

Human

Clone :

LF61

Isotype :

IgG1

Storage :

4 C, store in dark

Description :

CD103 (ITGAE, Integrin alpha E) is molecule that is expressed on mucosa-associated T lymphocytes and activated cells and on subet of TGF beta -1 cells. In particular, CD103 includes a 150kDa alpha chain and a 120kDa beta chain. CD103 is expressed by 0.5 to 2% of resting lymphocytes in peripheral blood and lymphoid organs. CD103 antibody stains a few bone marrow cells and, rarely, peripheral blood lymphocytes. CD103 is part of the integrin family which are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. ITGAE encodes an I-domain-containing alpha integrin that undergoes post-translational cleavage in the extracellular domain, yielding disulfide-linked heavy and light chains. In combination with the beta 7 integrin, CD103 protein forms the E-cadherin binding integrin known as the human mucosal lymphocyte-1 antigen. CD103 is preferentially expressed in human intestinal intraepithelial lymphocytes (IEL), and in addition to a role in adhesion, it may serve as an accessory molecule for IEL activation. Diseases associated with CD103 dysfunction include hairy cell leukemia and splenic marginal zone lymphoma.

Immunogen :

Human CD103

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: Assay-Dependent

Aliases :

A530055J10; alpha-E1; alpha-M290; aM290; antigen CD103; antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide; CD103; DC; DCs; HML-1 antigen; human mucosal lymphocyte antigen 1, alpha polypeptide; HUMINAE; integrin alpha E; integrin alpha E, epithelial-associated; integrin alpha E1, epithelial-associated; integrin alpha M290; Integrin alpha-E; Integrin alpha-E heavy chain; Integrin alpha-E light chain; Integrin alpha-IEL; integrin subunit alpha E; integrin, alpha E; integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide); integrin, alpha E, epithelial-associated; Intregrin alpha E2; Itgae; MGC141996; Mucosal lymphocyte 1 antigen