CD7 Monoclonal Antibody (CD7-6B7), PE | Invitrogen MHCD0704 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CD7 Monoclonal Antibody (CD7-6B7), PE

catalog :

MHCD0704

quantity :

0.5 mL

price :

US 396

clonality :

monoclonal

host :

mouse

conjugate :

clone name :

CD7-6B7

reactivity :

human, mouse

application :

flow cytometry

more info or order :

Invitrogen product webpage

citations: 3

Published Application/Species/Sample/Dilution	Reference
flow cytometry; human; tbl 1	Stacchini A, Aliberti S, Pacchioni D, Demurtas A, Isolato G, Gazzera C, et al. Flow cytometry significantly improves the diagnostic value of fine needle aspiration cytology of lymphoproliferative lesions of salivary glands. Cytopathology. 2014;25:231-40 pubmed publisher
flow cytometry; human; fig s5	Sanz E, Muñoz A N, Monserrat J, Van Den Rym A, Escoll P, Ranz I, et al. Ordering human CD34+CD10-CD19+ pre/pro-B-cell and CD19- common lymphoid progenitor stages in two pro-B-cell development pathways. Proc Natl Acad Sci U S A. 2010;107:5925-30 pubmed publisher
	Okoye Okafor U, Bartholdy B, Cartier J, Gao E, Pietrak B, Rendina A, et al. New IDH1 mutant inhibitors for treatment of acute myeloid leukemia. Nat Chem Biol. 2015;11:878-86 pubmed publisher

product information

Product Type :

Antibody

Product Name :

CD7 Monoclonal Antibody (CD7-6B7), PE

Catalog # :

MHCD0704

Quantity :

0.5 mL

Price :

US 396

Clonality :

Monoclonal

Purity :

purified

Host :

Mouse

Reactivity :

Human

Applications :

Flow Cytometry: Assay-Dependent

Species :

Human

Clone :

CD7-6B7

Isotype :

IgG2a

Storage :

4° C, store in dark

Description :

CD7 (gp40, Leu9) is a 40 kDa member of the immunoglobulin gene superfamily. CD7 contains N-terminal amino acids 1-107 are highly homologous to Ig kappa-L chains whereas the carboxy-terminal region of the extracellular domain is proline-rich and has been postulated to form a stalk from which the Ig domain projects. CD7 is expressed on the majority of immature and mature T-lymphocytes, and T cell leukemia. Further, CD7 is also found on natural killer cells, a small subpopulation of normal B cells and on malignant B cells. Cross-linking surface CD7 positively modulates T cell and NK cell activity as measured by calcium fluxes, expression of adhesion molecules, cytokine secretion and proliferation. CD7 associates directly with phosphoinositol 3'-kinase. CD7 ligation induces production of D-3 phosphoinositides and tyrosine phosphorylation. Expression of CD7 is an important marker used in leukemia diagnostics.

Immunogen :

Human CD7

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: Assay-Dependent

Aliases :

Cd7; CD7 antigen; CD7 antigen (p41); Cd7 molecule; GP40; LEU-9; p41 protein; T-cell antigen CD7; T-cell leukemia antigen; T-cell surface antigen Leu-9; Tp40; TP41

more info or order :

Invitrogen product webpage