CD4 Monoclonal Antibody (S3.5), TRI-COLOR | Invitrogen MHCD0406 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CD4 Monoclonal Antibody (S3.5), TRI-COLOR

catalog :

MHCD0406

quantity :

0.5 mL

price :

US 299.00

clonality :

monoclonal

host :

mouse

conjugate :

tricolor

clone name :

S3.5

reactivity :

human

application :

flow cytometry

more info or order :

Invitrogen product webpage

citations: 13

Published Application/Species/Sample/Dilution	Reference
flow cytometry; human	Elliott G, Hong C, Xing X, Zhou X, Li D, Coarfa C, et al. Intermediate DNA methylation is a conserved signature of genome regulation. Nat Commun. 2015;6:6363 pubmed publisher
flow cytometry; human; fig 1	Xu H, Ye J, Chen Y, Zhang L, Huang J, Xian J, et al. Changes in the proportions of CD4(+)T cell subsets defined by CD127 and CD25 expression during HBV infection. Immunol Invest. 2012;41:290-303 pubmed publisher
flow cytometry; human; fig 2	Luiza Silva M, Campi Azevedo A, Batista M, Martins M, Avelar R, da Silveira Lemos D, et al. Cytokine signatures of innate and adaptive immunity in 17DD yellow fever vaccinated children and its association with the level of neutralizing antibody. J Infect Dis. 2011;204:873-83 pubmed publisher
flow cytometry; human	Marei A, Ghaemmaghami A, Renshaw P, Wiselka M, Barer M, Carr M, et al. Superior T cell activation by ESAT-6 as compared with the ESAT-6-CFP-10 complex. Int Immunol. 2005;17:1439-46 pubmed
flow cytometry; human; fig 4	Camara N, Sebille F, Lechler R. Human CD4+CD25+ regulatory cells have marked and sustained effects on CD8+ T cell activation. Eur J Immunol. 2003;33:3473-83 pubmed
flow cytometry; human; fig 1	Jiang S, Camara N, Lombardi G, Lechler R. Induction of allopeptide-specific human CD4+CD25+ regulatory T cells ex vivo. Blood. 2003;102:2180-6 pubmed
flow cytometry; human	Biswas P, Mantelli B, Sica A, Malnati M, Panzeri C, Saccani A, et al. Expression of CD4 on human peripheral blood neutrophils. Blood. 2003;101:4452-6 pubmed
flow cytometry; human	Venkatesan S, Petrovic A, Van Ryk D, Locati M, Weissman D, Murphy P. Reduced cell surface expression of CCR5 in CCR5Delta 32 heterozygotes is mediated by gene dosage, rather than by receptor sequestration. J Biol Chem. 2002;277:2287-301 pubmed
flow cytometry; human	Venkatesan S, Petrovic A, Locati M, Kim Y, Weissman D, Murphy P. A membrane-proximal basic domain and cysteine cluster in the C-terminal tail of CCR5 constitute a bipartite motif critical for cell surface expression. J Biol Chem. 2001;276:40133-45 pubmed
flow cytometry; human; fig 1	Sharron M, Pohlmann S, Price K, Lolis E, Tsang M, Kirchhoff F, et al. Expression and coreceptor activity of STRL33/Bonzo on primary peripheral blood lymphocytes. Blood. 2000;96:41-9 pubmed
flow cytometry; human; fig 2	Converso M, Bertero M, Vallario A, Caligaris Cappio F. Analysis of T-cell clones in systemic lupus erythematosus. Haematologica. 2000;85:118-23 pubmed
flow cytometry; human; fig 7	Verhasselt B, De Smedt M, Verhelst R, Naessens E, Plum J. Retrovirally transduced CD34++ human cord blood cells generate T cells expressing high levels of the retroviral encoded green fluorescent protein marker in vitro. Blood. 1998;91:431-40 pubmed
	Wang K, Guzman A, Yan Z, Zhang S, Hu M, Hamaneh M, et al. Ultra-High-Frequency Reprogramming of Individual Long-Term Hematopoietic Stem Cells Yields Low Somatic Variant Induced Pluripotent Stem Cells. Cell Rep. 2019;26:2580-2592.e7 pubmed publisher

product information

Product Type :

Antibody

Product Name :

CD4 Monoclonal Antibody (S3.5), TRI-COLOR

Catalog # :

MHCD0406

Quantity :

0.5 mL

Price :

US 299.00

Clonality :

Monoclonal

Purity :

purified

Host :

Mouse

Reactivity :

Human

Applications :

Flow Cytometry: Assay-Dependent

Species :

Human

Clone :

S3.5

Isotype :

IgG2a

Storage :

4° C, store in dark

Description :

The CD4 antigen is involved in the recognition of MHC class II molecules and is a co-receptor for HIV. CD4 is primarily expressed in a subset of T-lymphocytes, also referred to as T helper cells, but may also be expressed by other cells in the immune system, such as monocytes, macrophages, and dendritic cells. At the tissue level, CD4 expression may be detected in thymus, lymph nodes, tonsils, and spleen, and also in specific regions of the brain, gut, and other non-lymphoid tissues. CD4 functions to initiate or augment the early phase of T-cell activation through its association with the T-cell receptor complex and protein tyrosine kinase, Lck. It may also function as an important mediator of direct neuronal damage in infectious and immune-mediated diseases of the central nervous system. Multiple alternatively spliced transcripts have been identified in this gene [RefSeq, July 2017].

Immunogen :

Human CD4

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: Assay-Dependent

Aliases :

Activation B7-1 antigen; B7; B7.1; B7-1; BB1; B-lymphocyte activation antigen B7; CD28LG; CD28LG1; CD4; CD4 antigen; CD4 antigen (p55); CD4 antigen p55; Cd4 molecule; CD4 precursor; CD4 receptor; CD4, allele 1; cd4a; CD4mut; CD80; CD80 antigen (CD28 antigen ligand 1, B7-1 antigen); CD80 molecule; cell surface glycoprotein CD4; costimulatory factor CD80; costimulatory molecule variant IgV-CD80; CTLA-4 counter-receptor B7.1; fCD4; L3T4; LAB7; Leu-3; Ly-4; lymphocyte antigen CD4; lymphocyte antigen CD4 precursor; membrane protein; p55; T-cell differentiation antigen L3T4; T-cell surface antigen T4/Leu-3; T-cell surface glycoprotein CD4; T-cell surface glycoprotein CD4 precursor (T-cell surface antigen T4/Leu-3) (T-cell differentiation antigen L3T4); T-lymphocyte activation antigen CD80; W3/25; W3/25 antigen

more info or order :

Invitrogen product webpage