CD4 Monoclonal Antibody (S3.5), PE | Invitrogen MHCD0404-4 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CD4 Monoclonal Antibody (S3.5), PE

catalog :

MHCD0404-4

quantity :

2 mL

price :

US 1168.00

clonality :

monoclonal

host :

mouse

conjugate :

clone name :

S3.5

reactivity :

human

application :

flow cytometry

citations: 15

Reference
Fischer D, Ansari M, Wagner K, Jarosch S, Huang Y, Mayr C, et al. Single-cell RNA sequencing reveals ex vivo signatures of SARS-CoV-2-reactive T cells through 'reverse phenotyping'. Nat Commun. 2021;12:4515 pubmed publisher
Chutipongtanate A, Prukviwat S, Pongsakul N, Srisala S, Kamanee N, Arpornsujaritkun N, et al. Effects of Desflurane and Sevoflurane anesthesia on regulatory T cells in patients undergoing living donor kidney transplantation: a randomized intervention trial. BMC Anesthesiol. 2020;20:215 pubmed publisher
Vanichapol T, Chiangjong W, Panachan J, Anurathapan U, Chutipongtanate S, Hongeng S. Secretory High-Mobility Group Box 1 Protein Affects Regulatory T Cell Differentiation in Neuroblastoma Microenvironment In Vitro. J Oncol. 2018;2018:7946021 pubmed publisher
Iwata A, Durai V, Tussiwand R, BriseÃ±o C, Wu X, Grajales Reyes G, et al. Quality of TCR signaling determined by differential affinities of enhancers for the composite BATF-IRF4 transcription factor complex. Nat Immunol. 2017;18:563-572 pubmed publisher
Spivak A, Larragoite E, Coletti M, Macedo A, Martins L, Bosque A, et al. Janus kinase inhibition suppresses PKC-induced cytokine release without affecting HIV-1 latency reversal ex vivo. Retrovirology. 2016;13:88 pubmed publisher
Kmiec D, Iyer S, Stürzel C, Sauter D, Hahn B, Kirchhoff F. Vpu-Mediated Counteraction of Tetherin Is a Major Determinant of HIV-1 Interferon Resistance. MBio. 2016;7: pubmed publisher
Xing Y, Cao R, Hu H. TLR and NLRP3 inflammasome-dependent innate immune responses to tumor-derived autophagosomes (DRibbles). Cell Death Dis. 2016;7:e2322 pubmed publisher
St Gelais C, Roger J, Wu L. Non-POU Domain-Containing Octamer-Binding Protein Negatively Regulates HIV-1 Infection in CD4(+) T Cells. AIDS Res Hum Retroviruses. 2015;31:806-16 pubmed publisher
de Carvalho J, de Castro R, da Silva E, Silveira P, da Silva JanuÃ¡rio M, Arruda E, et al. Nef neutralizes the ability of exosomes from CD4+ T cells to act as decoys during HIV-1 infection. PLoS ONE. 2014;9:e113691 pubmed publisher
Haldar M, Kohyama M, So A, Kc W, Wu X, BriseÃ±o C, et al. Heme-mediated SPI-C induction promotes monocyte differentiation into iron-recycling macrophages. Cell. 2014;156:1223-1234 pubmed publisher
Pimentel J, Chaves D, Araújo A, de Araújo E, da Silva Fraporti L, Neves W, et al. Anti-inflammatory/regulatory cytokine microenvironment mediated by IL-4 and IL-10 coordinates the immune response in hemophilia A patients infected chronically with hepatitis C virus. J Med Virol. 2013;85:1009-18 pubmed publisher
Barbosa R, Silva S, Silva S, Melo A, Pedro E, Barbosa M, et al. Primary B-cell deficiencies reveal a link between human IL-17-producing CD4 T-cell homeostasis and B-cell differentiation. PLoS ONE. 2011;6:e22848 pubmed publisher
de Almeida C, de Lima T, Castro D, Torres K, da Silva Braga W, Peruhype Magalhães V, et al. Immunological/virological peripheral blood biomarkers and distinct patterns of sleeping quality in chronic hepatitis C patients. Scand J Immunol. 2011;73:486-95 pubmed publisher
Elsner L, Flügge P, Lozano J, Muppala V, Eiz Vesper B, Demiroglu S, et al. The endogenous danger signals HSP70 and MICA cooperate in the activation of cytotoxic effector functions of NK cells. J Cell Mol Med. 2010;14:992-1002 pubmed publisher
Cron R, Bort S, Wang Y, Brunvand M, Lewis D. T cell priming enhances IL-4 gene expression by increasing nuclear factor of activated T cells. J Immunol. 1999;162:860-70 pubmed

product information

Product Type :

Antibody

Product Name :

CD4 Monoclonal Antibody (S3.5), PE

Catalog # :

MHCD0404-4

Quantity :

2 mL

Price :

US 1168.00

Clonality :

Monoclonal

Purity :

purified

Host :

Mouse

Reactivity :

Human

Applications :

Flow Cytometry: Assay-Dependent

Species :

Human

Clone :

S3.5

Isotype :

IgG2a

Storage :

4 C, store in dark

Description :

The CD4 antigen is involved in the recognition of MHC class II molecules and is a co-receptor for HIV. CD4 is primarily expressed in a subset of T-lymphocytes, also referred to as T helper cells, but may also be expressed by other cells in the immune system, such as monocytes, macrophages, and dendritic cells. At the tissue level, CD4 expression may be detected in thymus, lymph nodes, tonsils, and spleen, and also in specific regions of the brain, gut, and other non-lymphoid tissues. CD4 functions to initiate or augment the early phase of T-cell activation through its association with the T-cell receptor complex and protein tyrosine kinase, Lck. It may also function as an important mediator of direct neuronal damage in infectious and immune-mediated diseases of the central nervous system. Multiple alternatively spliced transcripts have been identified in this gene [RefSeq, July 2017].

Immunogen :

Human CD4

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: Assay-Dependent

Aliases :

Activation B7-1 antigen; B7; B7.1; B7-1; BB1; B-lymphocyte activation antigen B7; CD28LG; CD28LG1; CD4; CD4 antigen; CD4 antigen (p55); CD4 antigen p55; Cd4 molecule; CD4 precursor; CD4 receptor; CD4, allele 1; cd4a; CD4mut; CD80; CD80 antigen (CD28 antigen ligand 1, B7-1 antigen); CD80 molecule; cell surface glycoprotein CD4; costimulatory factor CD80; costimulatory molecule variant IgV-CD80; CTLA-4 counter-receptor B7.1; fCD4; L3T4; LAB7; Leu-3; Ly-4; lymphocyte antigen CD4; lymphocyte antigen CD4 precursor; membrane protein; p55; T-cell differentiation antigen L3T4; T-cell surface antigen T4/Leu-3; T-cell surface glycoprotein CD4; T-cell surface glycoprotein CD4 precursor (T-cell surface antigen T4/Leu-3) (T-cell differentiation antigen L3T4); T-lymphocyte activation antigen CD80; W3/25; W3/25 antigen