CD23 Monoclonal Antibody (B3B4), APC | Invitrogen MCD2305 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CD23 Monoclonal Antibody (B3B4), APC

catalog :

MCD2305

quantity :

500 uL

price :

US 416.00

clonality :

monoclonal

host :

rat

conjugate :

APC

clone name :

B3B4

reactivity :

mouse

application :

flow cytometry

more info or order :

Invitrogen product webpage

citations: 10

Published Application/Species/Sample/Dilution	Reference
flow cytometry; mouse; loading ...; fig 1c	Yao Y, Huang W, Li X, Li X, Qian J, Han H, et al. Tespa1 Deficiency Dampens Thymus-Dependent B-Cell Activation and Attenuates Collagen-Induced Arthritis in Mice. Front Immunol. 2018;9:965 pubmed publisher
flow cytometry; mouse; loading ...	Schweighoffer E, Nys J, Vanes L, Smithers N, Tybulewicz V. TLR4 signals in B lymphocytes are transduced via the B cell antigen receptor and SYK. J Exp Med. 2017;214:1269-1280 pubmed publisher
flow cytometry; mouse	Jacque E, Schweighoffer E, Tybulewicz V, Ley S. BAFF activation of the ERK5 MAP kinase pathway regulates B cell survival. J Exp Med. 2015;212:883-92 pubmed publisher
flow cytometry; mouse	Jacque E, Schweighoffer E, Visekruna A, Papoutsopoulou S, Janzen J, Zillwood R, et al. IKK-induced NF-ÎºB1 p105 proteolysis is critical for B cell antibody responses to T cell-dependent antigen. J Exp Med. 2014;211:2085-101 pubmed publisher
flow cytometry; mouse; fig 2	Hayashi E, Granato A, Paiva L, Bertho A, Bellio M, Nobrega A. TLR4 promotes B cell maturation: independence and cooperation with B lymphocyte-activating factor. J Immunol. 2010;184:4662-72 pubmed publisher
flow cytometry; mouse; fig 6	Ellinghaus U, Rupec R, Pabst O, Ignatius R, Forster R, Dorken B, et al. IkappaBalpha is required for marginal zone B cell lineage development. Eur J Immunol. 2008;38:2096-105 pubmed publisher
	Curtiss M, Rosenberg A, Scharer C, Mousseau B, Benavides N, Bradley J, et al. Chitinase-3-like 1 regulates TH2 cells, TFH cells and IgE responses to helminth infection. Front Immunol. 2023;14:1158493 pubmed publisher
	Baur J, Otto C, Steger U, Klein Hessling S, Muhammad K, Pusch T, et al. The Transcription Factor NFATc1 Supports the Rejection of Heterotopic Heart Allografts. Front Immunol. 2018;9:1338 pubmed publisher
	Granato A, Hayashi E, Baptista B, Bellio M, Nobrega A. IL-4 regulates Bim expression and promotes B cell maturation in synergy with BAFF conferring resistance to cell death at negative selection checkpoints. J Immunol. 2014;192:5761-75 pubmed publisher
	Balkhi M, Willette Brown J, Zhu F, Chen Z, Liu S, Guttridge D, et al. IKK?-mediated signaling circuitry regulates early B lymphopoiesis during hematopoiesis. Blood. 2012;119:5467-77 pubmed publisher

product information

Product Type :

Antibody

Product Name :

CD23 Monoclonal Antibody (B3B4), APC

Catalog # :

MCD2305

Quantity :

500 uL

Price :

US 416.00

Clonality :

Monoclonal

Purity :

purified

Host :

Rat

Reactivity :

Mouse

Applications :

Flow Cytometry: Assay-dependent

Species :

Mouse

Clone :

B3B4

Isotype :

IgG2a

Storage :

4 C

Description :

CD23 is a 45 kDa glycoprotein which is present on a subpopulation of freshly isolated peripheral blood and tonsil B cells and strongly expressed on EBV-transformed B lymphoblasts. The CD23 molecule is identical to the low affinity IgE receptor found on B cells. Expression of CD23 has been detected in neoplastic cells from cases of B cell chronic lymphocyctic leukaemia and some cases of centroblastic/centrocytic lymphoma. CD23 is present on a subpopulation of freshly isolated peripheral blood and tonsil B cells and strongly expressed on EBV-transformed B lymphoblasts. Functionally, CD23 is involved in B cell growth and differentiation, and IgE production. Further, CD23 has a soluble form that is a potent mitogenic factor. Diseases associated with CD23 dysfunction include chronic conjunctivitis and chronic lymphocytic leukemia.

Immunogen :

Mouse CD23.

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: Assay-dependent

Aliases :

BLAST-2; CD23; CD23 antigen; CD23A; CLEC4J; C-type lectin domain family 4 member J; C-type lectin domain family 4, member J; Fc epsilon receptor II; FC epsilon RII; Fc fragment of IgE receptor II; Fc fragment of IgE, low affinity II, receptor for (CD23); Fc receptor alpha multiple ligand receptor; Fc receptor, IgE, low affinity II, alpha polypeptide; Fcalpha muR; Fcalpha RII; Fce2; fc-epsilon-RII; FCER2; Fcer2a; FceRII; IGEBF; Immunoglobulin E-binding factor; immunoglobulin epsilon-chain; low affinity immunoglobulin epsilon Fc receptor; Low affinity immunoglobulin epsilon Fc receptor membrane-bound form; Low affinity immunoglobulin epsilon Fc receptor soluble form; low-affinity IgE receptor; Ly-42; lymphocyte IgE receptor

more info or order :

Invitrogen product webpage