CD4 Monoclonal Antibody (RM4-5), FITC | Invitrogen MCD0401 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CD4 Monoclonal Antibody (RM4-5), FITC

catalog :

MCD0401

quantity :

1 mL

price :

124 USD

clonality :

monoclonal

host :

rat

conjugate :

FITC

clone name :

RM4-5

reactivity :

mouse

application :

flow cytometry

citations: 12

Published Application/Species/Sample/Dilution	Reference
flow cytometry; mouse; loading ...; fig 4b	Cheng Y, Zhu X, Wang X, Zhuang Q, Huyan X, Sun X, et al. Trichinella spiralis Infection Mitigates Collagen-Induced Arthritis via Programmed Death 1-Mediated Immunomodulation. Front Immunol. 2018;9:1566 pubmed publisher
flow cytometry; mouse; loading ...; fig 5a	Carrasco S, Hu S, Imai D, Kumar R, Sandusky G, Yang X, et al. Toll-like receptor 3 (TLR3) promotes the resolution of Chlamydia muridarum genital tract infection in congenic C57BL/6N mice. PLoS ONE. 2018;13:e0195165 pubmed publisher
flow cytometry; mouse; loading ...; fig 2d	Hammer A, Yang G, Friedrich J, Kovacs A, Lee D, Grave K, et al. Role of the receptor Mas in macrophage-mediated inflammation in vivo. Proc Natl Acad Sci U S A. 2016;113:14109-14114 pubmed
flow cytometry; mouse; tbl 1	Thompson J, Chu Y, Glass J, Tapp A, Brown S. The manganese superoxide dismutase mimetic, M40403, protects adult mice from lethal total body irradiation. Free Radic Res. 2010;44:529-40 pubmed publisher
flow cytometry; mouse; fig 4	Thompson J, Chu Y, Glass J, Brown S. Absence of IL-23p19 in donor allogeneic cells reduces mortality from acute GVHD. Bone Marrow Transplant. 2010;45:712-22 pubmed publisher
flow cytometry; mouse	Moulton R, Mashruwala M, Smith A, Lindsey D, Wetsel R, Haviland D, et al. Complement C5a anaphylatoxin is an innate determinant of dendritic cell-induced Th1 immunity to Mycobacterium bovis BCG infection in mice. J Leukoc Biol. 2007;82:956-67 pubmed
flow cytometry; mouse; fig 7	Haque A, Easton A, Smith D, O GARRA A, Van Rooijen N, Lertmemongkolchai G, et al. Role of T cells in innate and adaptive immunity against murine Burkholderia pseudomallei infection. J Infect Dis. 2006;193:370-9 pubmed
flow cytometry; mouse; fig 2	Kohu K, Sato T, Ohno S, Hayashi K, Uchino R, Abe N, et al. Overexpression of the Runx3 transcription factor increases the proportion of mature thymocytes of the CD8 single-positive lineage. J Immunol. 2005;174:2627-36 pubmed
flow cytometry; mouse	Spiekermann G, Nagler Anderson C. Oral administration of the bacterial superantigen staphylococcal enterotoxin B induces activation and cytokine production by T cells in murine gut-associated lymphoid tissue. J Immunol. 1998;161:5825-31 pubmed
	Annibaldi A, Wicky John S, Vanden Berghe T, Swatek K, Ruan J, Liccardi G, et al. Ubiquitin-Mediated Regulation of RIPK1 Kinase Activity Independent of IKK and MK2. Mol Cell. 2018;69:566-580.e5 pubmed publisher
	Wanchoo A, Voigt A, Sukumaran S, Stewart C, Bhattacharya I, Nguyen C. Single-cell analysis reveals sexually dimorphic repertoires of Interferon-γ and IL-17A producing T cells in salivary glands of Sjögren's syndrome mice. Sci Rep. 2017;7:12512 pubmed publisher
	Roche C, Smith A, Lindsey D, Meher A, Schluns K, Arora A, et al. The ?fbpA attenuated candidate vaccine from Mycobacterium tuberculosis, H37Rv primes for a stronger T-bet dependent Th1 immunity in mice. Tuberculosis (Edinb). 2011;91 Suppl 1:S96-104 pubmed publisher

product information

Product Type :

Antibody

Product Name :

CD4 Monoclonal Antibody (RM4-5), FITC

Catalog # :

MCD0401

Quantity :

1 mL

Price :

124 USD

Clonality :

Monoclonal

Purity :

purified

Host :

Rat

Reactivity :

Mouse

Applications :

Flow Cytometry: Assay Dependent

Species :

Mouse

Clone :

RM4-5

Isotype :

IgG2a

Storage :

4° C

Description :

The CD4 antigen is involved in the recognition of MHC class II molecules and is a co-receptor for HIV. CD4 is primarily expressed in a subset of T-lymphocytes, also referred to as T helper cells, but may also be expressed by other cells in the immune system, such as monocytes, macrophages, and dendritic cells. At the tissue level, CD4 expression may be detected in thymus, lymph nodes, tonsils, and spleen, and also in specific regions of the brain, gut, and other non-lymphoid tissues. CD4 functions to initiate or augment the early phase of T-cell activation through its association with the T-cell receptor complex and protein tyrosine kinase, Lck. It may also function as an important mediator of direct neuronal damage in infectious and immune-mediated diseases of the central nervous system. Multiple alternatively spliced transcripts have been identified in this gene [RefSeq, July 2017].

Immunogen :

Mouse CD4

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: Assay Dependent

Aliases :

CD4 antigen p55, CD4 receptor, T-cell surface antigen T4/Leu-3, T-cell surface glycoprotein CD4