CD58 Monoclonal Antibody (TS2/9) | Invitrogen MA5800 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CD58 Monoclonal Antibody (TS2/9)

catalog :

MA5800

quantity :

200 µg

price :

US 410.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

TS2/9

reactivity :

human

application :

western blot, immunohistochemistry, immunocytochemistry, neutralization, immunoprecipitation, flow cytometry, immunohistochemistry - frozen section, blocking or activating experiments

more info or order :

Invitrogen product webpage

citations: 14

Published Application/Species/Sample/Dilution	Reference
blocking or activating experiments; human	Fromm J, Kussick S, Wood B. Identification and purification of classical Hodgkin cells from lymph nodes by flow cytometry and flow cytometric cell sorting. Am J Clin Pathol. 2006;126:764-80 pubmed
	Nguyen C, Domma A, Zhang H, Kamil J. Endoplasmic Reticulum (ER) Reorganization and Intracellular Retention of CD58 Are Functionally Independent Properties of the Human Cytomegalovirus ER-Resident Glycoprotein UL148. J Virol. 2020;94: pubmed publisher
	Boissard F, Tosolini M, Ligat L, Quillet Mary A, Lopez F, Fourni xe9 J, et al. Nurse-like cells promote CLL survival through LFA-3/CD2 interactions. Oncotarget. 2017;8:52225-52236 pubmed publisher
	Yamamoto T, Nakane T, Doi S, Osaki T. Lipopolysaccharide signal transduction in oral keratinocytes--involvement of CD59 but not CD14. Cell Signal. 2003;15:861-9 pubmed
	Khayyamian S, Hutloff A, Büchner K, Grafe M, Henn V, Kroczek R, et al. ICOS-ligand, expressed on human endothelial cells, costimulates Th1 and Th2 cytokine secretion by memory CD4+ T cells. Proc Natl Acad Sci U S A. 2002;99:6198-203 pubmed
	Hansen A, Bouchelouche K, Olesen J. Human lung microvascular endothelial cells activate allogeneic T cells through an LFA-3-dependent, but CD86-independent mechanism. APMIS. 2001;109:849-56 pubmed
	Wang P, Malkovsky M. Different roles of the CD2 and LFA-1 T-cell co-receptors for regulating cytotoxic, proliferative, and cytokine responses of human V gamma 9/V delta 2 T cells. Mol Med. 2000;6:196-207 pubmed
	Douglas I, Leff A, Sperling A. CD4+ T cell and eosinophil adhesion is mediated by specific ICAM-3 ligation and results in eosinophil activation. J Immunol. 2000;164:3385-91 pubmed
	Itzhaky D, Raz N, Hollander N. The glycosylphosphatidylinositol-anchored form and the transmembrane form of CD58 associate with protein kinases. J Immunol. 1998;160:4361-6 pubmed
	Gollob J, Li J, Kawasaki H, Daley J, Groves C, Reinherz E, et al. Molecular interaction between CD58 and CD2 counter-receptors mediates the ability of monocytes to augment T cell activation by IL-12. J Immunol. 1996;157:1886-93 pubmed
	Bruggers C, Patel D, Scearce R, Whichard L, Haynes B, Singer K. AD2, a human molecule involved in the interaction of T cells with epidermal keratinocytes and thymic epithelial cells. J Immunol. 1995;154:2012-22 pubmed
	Altomonte M, Gloghini A, Bertola G, Gasparollo A, Carbone A, Ferrone S, et al. Differential expression of cell adhesion molecules CD54/CD11a and CD58/CD2 by human melanoma cells and functional role in their interaction with cytotoxic cells. Cancer Res. 1993;53:3343-8 pubmed
	Sanchez Madrid F, Krensky A, Ware C, Robbins E, Strominger J, Burakoff S, et al. Three distinct antigens associated with human T-lymphocyte-mediated cytolysis: LFA-1, LFA-2, and LFA-3. Proc Natl Acad Sci U S A. 1982;79:7489-93 pubmed
	Hale L, Martin M, McCollum D, Nunley J, Springer T, Singer K, et al. Immunohistologic analysis of the distribution of cell adhesion molecules within the inflammatory synovial microenvironment. Arthritis Rheum. 1989;32:22-30 pubmed

product information

Product Type :

Antibody

Product Name :

CD58 Monoclonal Antibody (TS2/9)

Catalog # :

MA5800

Quantity :

200 µg

Price :

US 410.00

Clonality :

Monoclonal

Purity :

protein A

Host :

Mouse

Reactivity :

Human, Mouse

Applications :

Flow Cytometry: Assay-dependent, Immunocytochemistry: 1:10-1:100, Immunohistochemistry (Frozen): Assay-dependent, Immunoprecipitation: Assay-dependent, Neutralization: Assay-dependent, Western Blot: 1:100-1:500

Species :

Human, Mouse

Clone :

TS2/9

Isotype :

IgG1

Storage :

-20°C

Description :

This gene encodes a member of the immunoglobulin superfamily. The encoded protein is a ligand of the T lymphocyte CD2 protein, and functions in adhesion and activation of T lymphocytes. The protein is localized to the plasma membrane. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jan 2009]

Immunogen :

Human Leukocyte Function Antigen-3

Format :

Liquid

Applications w/Dilutions :

Aliases :

Ag3; CD305; CD58; CD58 antigen; CD58 antigen, (lymphocyte function-associated antigen 3); CD58 molecule; FLJ23181; FLJ43722; LAIR1; LAIR-1; LFA3; LFA-3; Lymphocyte function-associated antigen 3; membrane receptor; RP5-1086K13.2; surface glycoprotein LFA-3

more info or order :

Invitrogen product webpage