T-bet Recombinant Rabbit Monoclonal Antibody (9M7X6) | Invitrogen MA5-58224 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

T-bet Recombinant Rabbit Monoclonal Antibody (9M7X6)

catalog :

MA5-58224

quantity :

100 uL

price :

US 419.00

clonality :

recombinant

host :

domestic rabbit

conjugate :

nonconjugated

clone name :

9M7X6

reactivity :

human, mouse, rat

application :

western blot, ELISA, immunoprecipitation

product information

Product Type :

Antibody

Product Name :

T-bet Recombinant Rabbit Monoclonal Antibody (9M7X6)

Catalog # :

MA5-58224

Quantity :

100 uL

Price :

US 419.00

Clonality :

Recombinant Monoclonal

Purity :

protein A

Host :

Rabbit

Reactivity :

Human, Mouse, Rat

Applications :

ELISA: 1 ug/mL, Immunoprecipitation: 0.5-4 ug for 200-400 ug extracts of whole cells, Western Blot: 1:500-1:1,000

Species :

Human, Mouse, Rat

Clone :

9M7X6

Isotype :

IgG

Storage :

-20 C, Avoid Freeze/Thaw Cycles

Description :

T-bet, also known as TBX21, is a T-cell specific transcription factor containing a single T-box DNA-binding domain. It controls the expression of the TH1 cytokine, interferon-gamma. Both Th1 and Th17 cells are crucial in immune regulation and autoimmune disease development. T-bet initiates Th1 lineage development from naive Th precursor cells and directs T cell differentiation to Th1 versus Th17. T-bet is cooperating with Stat4 (signal tranducer and activator of transcription 4) in programming chromatin architecture for Th1 gene expression. Genetic variations in T-bet are associated with susceptibility to aspirin-induced asthma and nasal polyps.

Immunogen :

Recombinant fusion protein containing a sequence corresponding to amino acids 322-535 of human T-bet/Tbx21 (NP_037483.1).

Format :

Liquid

Applications w/Dilutions :

ELISA: 1 ug/mL, Immunoprecipitation: 0.5-4 ug for 200-400 ug extracts of whole cells, Western Blot: 1:500-1:1,000

Aliases :

HGNC:11599; LOW QUALITY PROTEIN: T-box transcription factor TBX21; Tbet; T-bet; TBLYM; T-box 21; T-box expressed in T cells; T-box protein 21; T-box transcription factor 21; T-box transcription factor TBX21; TBT1; TBX21; T-cell-specific T-box transcription factor T-bet; T-PET; transcription factor TBLYM; transcription factor T-box 21