P-cadherin Recombinant Rabbit Monoclonal Antibody (8J5J8) | Invitrogen MA5-58201 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

P-cadherin Recombinant Rabbit Monoclonal Antibody (8J5J8)

catalog :

MA5-58201

quantity :

20 uL

price :

US 169.00

clonality :

recombinant

host :

domestic rabbit

conjugate :

nonconjugated

clone name :

8J5J8

reactivity :

human

application :

western blot, ELISA

product information

Product Type :

Antibody

Product Name :

P-cadherin Recombinant Rabbit Monoclonal Antibody (8J5J8)

Catalog # :

MA5-58201

Quantity :

20 uL

Price :

US 169.00

Clonality :

Recombinant Monoclonal

Purity :

protein A

Host :

Rabbit

Reactivity :

Human

Applications :

ELISA: 1 ug/mL, Western Blot: 1:1,500-1:6,000

Species :

Human

Clone :

8J5J8

Isotype :

IgG

Storage :

-20 C, Avoid Freeze/Thaw Cycles

Description :

P-cadherin, also known as Cadherin-3, is a Type 1 cadherin protein that belongs to the cadherin superfamily. Type 1 cadherins are single-pass transmembrane proteins that have 5 extracellular cadherin repeats and an intracellular domain that binds p120-catenin and beta-catenin. Cadherins are calcium-dependent cell-cell adhesion glycoproteins responsible for a range of processes including development, wound healing, cell-cell signaling, cell growth and differentiation. P-cadherin is expressed in human fetal structures, and in adult tissues such as the basal layer of the epidermis, breast, prostate, ovary, cervix, hair follicle, and corneal endothelium. P-cadherin expression has also been reported on embryonic stem cells, and stem cells of the normal mammary gland, and hair follicle. Overexpression of P-cadherin has been associated with poor prognosis in breast, prostate, ovary, colon, and stomach carcinomas. Mutations in CDH3 are associated with congential hypotrichosis with juvenile macular dystrophy.

Immunogen :

Recombinant fusion protein containing a sequence corresponding to amino acids 108-654 of human P-cadherin (NP_001784.2).

Format :

Liquid

Applications w/Dilutions :

ELISA: 1 ug/mL, Western Blot: 1:1,500-1:6,000

Aliases :

AI385538; CADH3; cadherin 15, M-cadherin (myotubule); cadherin 3; cadherin 3, type 1, P-cadherin (placental); cadherin-3; Cadp; calcium-dependent adhesion protein, placental; CDH3; CDHP; HJMD; PCAD; P-cadherin; Placental cadherin; Placental-cadherin; RPE-specific cadherin