Dectin 1 Recombinant Rabbit Monoclonal Antibody (7L10N4) | Invitrogen MA5-58111 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

Dectin 1 Recombinant Rabbit Monoclonal Antibody (7L10N4)

catalog :

MA5-58111

quantity :

20 uL

price :

US 169.00

clonality :

recombinant

host :

domestic rabbit

conjugate :

nonconjugated

clone name :

7L10N4

reactivity :

mouse, rat

application :

immunohistochemistry, immunohistochemistry - paraffin section

product information

Product Type :

Antibody

Product Name :

Dectin 1 Recombinant Rabbit Monoclonal Antibody (7L10N4)

Catalog # :

MA5-58111

Quantity :

20 uL

Price :

US 169.00

Clonality :

Recombinant Monoclonal

Purity :

protein A

Host :

Rabbit

Reactivity :

Mouse, Rat

Applications :

ELISA: 1 ug/mL, Immunohistochemistry (Paraffin): 1:50-1:200

Species :

Mouse, Rat

Clone :

7L10N4

Isotype :

IgG

Storage :

-20 C, Avoid Freeze/Thaw Cycles

Description :

CLEC7A, also known as dectin-1, is a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily and is predominantly expressed on myeloid cells. It is a small glycoprotein type II membrane receptor with an extracellular C-type lectin-like domain fold and a cytoplasmic domain with an immunoreceptor tyrosine-based activation motif (ITAM). CLEC7A functions as a pattern-recognition receptor that recognizes a variety of beta-1,3-linked and beta-1,6-linked glucans from fungi and plants, and in this way plays a role in innate immune response. Upon fungal exposure, CLEC7A activates Syk tyrosine kinase, triggering a massive oxidative burst through the formation of reactive oxygen species.

Immunogen :

Recombinant fusion protein containing a sequence corresponding to amino acids 66-247 of human Dectin-1 (NP_922938.1).

Format :

Liquid

Applications w/Dilutions :

ELISA: 1 ug/mL, Immunohistochemistry (Paraffin): 1:50-1:200

Aliases :

Beta-glucan receptor; beta-GR; BGR; CANDF4; CD369; CLEC7A; Clec7b; CLECSF12; C-type (calcium dependent, carbohydrate recognition domain) lectin, superfamily member 12; C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamily member 12; C-type lectin domain family 7 member A; C-type lectin domain family 7, member A; C-type lectin superfamily member 12; DC-associated C-type lectin 1; DECTIN1; dectin-1; Dendritic cell-associated C-type lectin 1; dendritic cell-associated C-type lectin-1; lectin-like receptor 1; RGD1565140; SCARE2; UNQ539/PRO1082