This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
NOTCH3 Recombinant Rabbit Monoclonal Antibody (1A7L4)
catalog :
MA5-57980
quantity :
100 uL
price :
US 419.00
clonality :
recombinant
host :
domestic rabbit
conjugate :
nonconjugated
clone name :
1A7L4
reactivity :
human
application :
western blot, ELISA
product information
Product Type :
Antibody
Product Name :
NOTCH3 Recombinant Rabbit Monoclonal Antibody (1A7L4)
Catalog # :
MA5-57980
Quantity :
100 uL
Price :
US 419.00
Clonality :
Recombinant Monoclonal
Purity :
protein A
Host :
Rabbit
Reactivity :
Human
Applications :
ELISA: 1 ug/mL, Western Blot: 1:500-1:1,000
Species :
Human
Clone :
1A7L4
Isotype :
IgG
Storage :
-20 C, Avoid Freeze/Thaw Cycles
Description :
NOTCH3 is the third discovered human homologue of the Drosophilia melanogaster type I membrane protein notch. In Drosophilia, notch interaction (with its cell-bound ligands delta, serrate) establishes an intercellular signalling pathway that plays a key role in neural development. Homologues of the notch-ligands have also been identified in human. NOTCH3 functions as a receptor for membrane-bound ligands Jagged1, Jagged2, and Delta1 to regulate cell-fate determination. Mutations in NOTCH3 have been identified as the underlying cause of cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL).
Immunogen :
A synthetic peptide corresponding to a sequence within amino acids 2222-2321 of human NOTCH3 (NP_000426.2).
Format :
Liquid
Applications w/Dilutions :
ELISA: 1 ug/mL, Western Blot: 1:500-1:1,000
Aliases :
AW229011; CADASIL; CADASIL1; CASIL; hpbk; IMF2; LMNS; N3; Neurogenic locus notch homolog protein 3; notch 3; Notch 3 extracellular truncation; Notch 3 intracellular domain; Notch gene homolog 3; Notch homolog 3; NOTCH3
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA