EpoR Recombinant Rabbit Monoclonal Antibody (4O8U2) | Invitrogen MA5-57950 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

EpoR Recombinant Rabbit Monoclonal Antibody (4O8U2)

catalog :

MA5-57950

quantity :

100 uL

price :

US 419.00

clonality :

recombinant

host :

domestic rabbit

conjugate :

nonconjugated

clone name :

4O8U2

reactivity :

human

application :

western blot, ELISA

product information

Product Type :

Antibody

Product Name :

EpoR Recombinant Rabbit Monoclonal Antibody (4O8U2)

Catalog # :

MA5-57950

Quantity :

100 uL

Price :

US 419.00

Clonality :

Recombinant Monoclonal

Purity :

protein A

Host :

Rabbit

Reactivity :

Human

Applications :

ELISA: 1 ug/mL, Western Blot: 1:1,000-1:4,000

Species :

Human

Clone :

4O8U2

Isotype :

IgG

Storage :

-20 C, Avoid Freeze/Thaw Cycles

Description :

EpoR encodes the erythropoietin receptor, which belongs to the cytokine receptor family. When erythropoietin binds to this receptor, it activates the Jak2 tyrosine kinase, which in turn activates various intracellular pathways including Ras/MAP kinase, phosphatidylinositol 3-kinase, and STAT transcription factors. The stimulated erythropoietin receptor plays a role in the survival of erythroid cells. Defects in this gene may result in erythroleukemia and familial erythrocytosis. Dysregulation of this gene may also affect the growth of certain tumors. Multiple transcript variants are produced as a result of alternate splicing. Diseases associated with EPOR include Erythrocytosis, Familial, 1 and Erythroleukemia.

Immunogen :

Recombinant fusion protein containing a sequence corresponding to amino acids 25-249 of human EPOR (NP_000112.1).

Format :

Liquid

Applications w/Dilutions :

ELISA: 1 ug/mL, Western Blot: 1:1,000-1:4,000

Aliases :

EPO R; EPOR; EPO-R; Erythropoietin receptor; pEpoR