ADSL Recombinant Rabbit Monoclonal Antibody (8J9E10) | Invitrogen MA5-57909 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

ADSL Recombinant Rabbit Monoclonal Antibody (8J9E10)

catalog :

MA5-57909

quantity :

20 uL

price :

US 169.00

clonality :

recombinant

host :

domestic rabbit

conjugate :

nonconjugated

clone name :

8J9E10

reactivity :

human

application :

western blot, ELISA

product information

Product Type :

Antibody

Product Name :

ADSL Recombinant Rabbit Monoclonal Antibody (8J9E10)

Catalog # :

MA5-57909

Quantity :

20 uL

Price :

US 169.00

Clonality :

Recombinant Monoclonal

Purity :

protein A

Host :

Rabbit

Reactivity :

Human

Applications :

ELISA: 1 ug/mL, Western Blot: 1:1,500-1:6,000

Species :

Human

Clone :

8J9E10

Isotype :

IgG

Storage :

-20 C, Avoid Freeze/Thaw Cycles

Description :

ADSL (adenylosuccinate lyase), also known as AMPS, ASL or ASASE, is a 484 amino acid protein that is involved in both purine biosynthesis and in the formation of adenosine monophosphate (AMP) from inosine monophosphate. Expressed ubiquitously, ADSL catalyzes two key reactions in AMP biosynthesis, namely the removal of a fumarate from succinylaminoimidazole carboxamide (SAICA) ribotide to give aminoimidazole carboxamide ribotide (AICA) and the subsequent removal of fumarate from adenylosuccinate to yield AMP. Defects in the gene encoding ADSL are the cause of adenylosuccinase deficiency (ADSL deficiency), an autosomal recessive disorder characterized by epilepsy, growth retardation and muscular wasting. Multiple isoforms of ADSL exist due to alternative splicing events.

Immunogen :

Recombinant fusion protein containing a sequence corresponding to amino acids 1-484 of human ADSL (NP_000017.1).

Format :

Liquid

Applications w/Dilutions :

ELISA: 1 ug/mL, Western Blot: 1:1,500-1:6,000

Aliases :

2510006M18Rik; Adenylosuccinase; adenylosuccinate lyase; adenylosuccinate lyase 1; Adl; Adsl; AMPS; argininosuccinase; argininosuccinate lyase; Arginosuccinase; ASAL; ASase; ASL; null; test; unnamed protein product