PTBP1 Recombinant Rabbit Monoclonal Antibody (24GB1095) | Invitrogen MA5-57653 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

PTBP1 Recombinant Rabbit Monoclonal Antibody (24GB1095)

catalog :

MA5-57653

quantity :

20 uL

price :

US 189.00

clonality :

recombinant

host :

domestic rabbit

conjugate :

nonconjugated

clone name :

24GB1095

reactivity :

human, mouse, rat

application :

western blot, flow cytometry

product information

Product Type :

Antibody

Product Name :

PTBP1 Recombinant Rabbit Monoclonal Antibody (24GB1095)

Catalog # :

MA5-57653

Quantity :

20 uL

Price :

US 189.00

Clonality :

Recombinant Monoclonal

Purity :

Affinity chromatography

Host :

Rabbit

Reactivity :

Human, Mouse, Rat

Applications :

Flow Cytometry: 1:2,000, Western Blot: 1:1,000-1:5,000

Species :

Human, Mouse, Rat

Clone :

24GB1095

Isotype :

IgG

Storage :

-20 C

Description :

This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA-binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has four repeats of quasi-RNA recognition motif (RRM) domains that bind RNAs. This protein binds to the intronic polypyrimidine tracts that requires pre-mRNA splicing and acts via the protein degradation ubiquitin-proteasome pathway. It may also promote the binding of U2 snRNP to pre-mRNAs. This protein is localized in the nucleoplasm and it is also detected in the perinucleolar structure. Alternatively spliced transcript variants encoding different isoforms have been described.

Immunogen :

A synthesized peptide derived from human PTBP1 (aa 20-68)

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 1:2,000, Western Blot: 1:1,000-1:5,000

Aliases :

57 kDa RNA-binding protein PPTB-1; AA407203; AL033359; Heterogeneous nuclear ribonucleoprotein I; heterogeneous nuclear ribonucleoprotein polypeptide I; hnRNP I; HNRNPI; HNRNP-I; HNRPI; MGC10830; MGC8461; polypyrimidine tract binding protein (heterogeneous nuclear ribonucleoprotein I); polypyrimidine tract binding protein 1; polypyrimidine tract-binding protein; polypyrimidine tract-binding protein 1; polypyrimidine-tract binding protein; pPTB; PTB; PTB-1; PTB2; PTB3; PTB4; PTBP1; PTB-T; Pybp; Pybp1; Pybp2; pyrimidine binding protein 1; pyrimidine binding protein 2; RNA-binding protein