PABPN1 Recombinant Rabbit Monoclonal Antibody (24GB365) | Invitrogen MA5-57610 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

PABPN1 Recombinant Rabbit Monoclonal Antibody (24GB365)

catalog :

MA5-57610

quantity :

100 uL

price :

US 539.00

clonality :

recombinant

host :

domestic rabbit

conjugate :

nonconjugated

clone name :

24GB365

reactivity :

human, mouse, rat

application :

western blot, immunocytochemistry, flow cytometry

product information

Product Type :

Antibody

Product Name :

PABPN1 Recombinant Rabbit Monoclonal Antibody (24GB365)

Catalog # :

MA5-57610

Quantity :

100 uL

Price :

US 539.00

Clonality :

Recombinant Monoclonal

Purity :

Affinity chromatography

Host :

Rabbit

Reactivity :

Human, Mouse, Rat

Applications :

Flow Cytometry: 1:2,000, Immunocytochemistry: 1:100-1:1,000, Western Blot: 1:1,000-1:5,000

Species :

Human, Mouse, Rat

Clone :

24GB365

Isotype :

IgG

Storage :

-20 C

Description :

This gene encodes an abundant nuclear protein that binds with high affinity to nascent poly(A) tails. The protein is required for progressive and efficient polymerization of poly(A) tails at the 3' ends of eukaryotic transcripts and controls the size of the poly(A) tail to about 250 nt. At steady-state, this protein is localized in the nucleus whereas a different poly(A) binding protein is localized in the cytoplasm. This gene contains a GCG trinucleotide repeat at the 5' end of the coding region, and expansion of this repeat from the normal 6 copies to 8-13 copies leads to autosomal dominant oculopharyngeal muscular dystrophy (OPMD) disease. Related pseudogenes have been identified on chromosomes 19 and X. Read-through transcription also exists between this gene and the neighboring upstream BCL2-like 2 (BCL2L2) gene.

Immunogen :

A synthesized peptide derived from human PABPN1 (aa 4-31)

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 1:2,000, Immunocytochemistry: 1:100-1:1,000, Western Blot: 1:1,000-1:5,000

Aliases :

mPABII; Nuclear poly(A)-binding protein 1; OPMD; PAB2; PABII; PABP2; PABP-2; Pabp3; PABPN1; poly(A) binding protein 2; poly(A) binding protein II; poly(A) binding protein nuclear 1; poly(A) binding protein, nuclear 1; poly(A)-binding protein 2; poly(A)-binding protein II; polyA binding protein II; polyadenylate-binding nuclear protein 1; Polyadenylate-binding protein 2