This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
PLSCR1 Recombinant Rabbit Monoclonal Antibody (24GB1550)
catalog :
MA5-57581
quantity :
20 uL
price :
US 189.00
clonality :
recombinant
host :
domestic rabbit
conjugate :
nonconjugated
clone name :
24GB1550
reactivity :
human, mouse, rat
application :
western blot, flow cytometry
product information
Product Type :
Antibody
Product Name :
PLSCR1 Recombinant Rabbit Monoclonal Antibody (24GB1550)
Catalog # :
MA5-57581
Quantity :
20 uL
Price :
US 189.00
Clonality :
Recombinant Monoclonal
Purity :
Affinity chromatography
Host :
Rabbit
Reactivity :
Human, Mouse, Rat
Applications :
Flow Cytometry: 1:2,000, Western Blot: 1:1,000-1:5,000
Species :
Human, Mouse, Rat
Clone :
24GB1550
Isotype :
IgG
Storage :
-20 C
Description :
The calcium-dependent plasma membrane protein phospholipid scramblase 1 (PLSCR1) contributes to the transbilayer movement of phosphatidylserine and other membrane phospholipids upon influx of calcium into the cytosol. This movement results in plasma membrane phospholipid remodelling and surface exposure of phosphatidylserine in injured or apoptotic cells, which leads to cell death. Interferons and other cytokines induce expression of PLSCR1, implying that PLSCR1 also functions in cytokine signaling pathways. EGF stilmulation results in tyrosine phosphorylation of PLSCR1 on tyrosines 69 and 74, which allows it to interact with Shc, and thereby connecting Src kinase activation to stimulation of the EGF receptor.
Immunogen :
A synthesized peptide derived from human Scramblase 1 (aa 20-55)
Format :
Liquid
Applications w/Dilutions :
Flow Cytometry: 1:2,000, Western Blot: 1:1,000-1:5,000
Aliases :
ca(2+)-dependent phospholipid scramblase 1; Erythrocyte phospholipid scramblase; MmTRA1a; MmTRA1b; NOR1; Phospholipid scramblase 1; phospholipid scramblase 2; PL scramblase 1; Plscr1; Tra1; Tra1a; Tra1b; transplantability-associated protein 1; Tras1; Tras2
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA