PKC alpha/beta/gamma Recombinant Rabbit Monoclonal Antibody (24GB885)

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

PKC alpha/beta/gamma Recombinant Rabbit Monoclonal Antibody (24GB885)

catalog :

MA5-57173

quantity :

100 uL

price :

US 479.00

clonality :

recombinant

host :

domestic rabbit

conjugate :

nonconjugated

clone name :

24GB885

reactivity :

human, mouse, rat

application :

western blot, immunocytochemistry, flow cytometry

product information

Product Type :

Antibody

Product Name :

PKC alpha/beta/gamma Recombinant Rabbit Monoclonal Antibody (24GB885)

Catalog # :

MA5-57173

Quantity :

100 uL

Price :

US 479.00

Clonality :

Recombinant Monoclonal

Purity :

Affinity chromatography

Host :

Rabbit

Reactivity :

Human, Mouse, Rat

Applications :

Flow Cytometry: 1:2,000, Immunocytochemistry: 1:100-1:1,000, Western Blot: 1:1,000-1:5,000

Species :

Human, Mouse, Rat

Clone :

24GB885

Isotype :

IgG

Storage :

-20 C

Description :

Protein Kinase c alpha (PKC alpha) is an 77 kDa member of the conventional group (cPKCs: sensitive to calcium, diacylglycerol, phosphatidylserine and phorbol esters) of the PKC family of serine/ threonine kinases that are involved in a wide range of physiological processes including mitogenesis, cell survival and transcriptional regulation. PKC alpha is an ubiquitously expressed PKC isozyme that has been implicated in the regulation of a broad range of cellular functions including proliferation, differentiation, development, migration, cell cell adhesion, cell extracellular matrix adhesion, and solute transport. The activation loop threonine (threonine 497 in PKC alpha) of conventional PKCs is phosphorylated by phosphoinositide dependent kinase 1 (PDK1). This phosphorylation is necessary for the autophosphorylation of threonine 638 in the carboxy terminus of PKC alpha, a step that is critical for regulating the rate of PKC alpha dephosphorylation and inactivation.

Immunogen :

A synthesized peptide derived from human PKC (aa 300-500)

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 1:2,000, Immunocytochemistry: 1:100-1:1,000, Western Blot: 1:1,000-1:5,000

Aliases :

A130082F03Rik; cAMP-dependent protein kinase catalytic subunit alpha; cAMP-dependent protein kinase catalytic subunit alpha, isoform 1; cAMP-dependent protein kinase catalytic subunit C alpha; Cs-PKA; PKA C-alpha; Pkaca; PKC; PKCA1; Pkcb; PKC-B; PKC-beta; PKCC; PKCD; PKCG; PKCgamma; PKC-gamma; PKCI; PPNAD4; PRKACA; Prkc; Prkcb; Prkcb1; Prkcb2; Prkcc; Prkcg; protein kinase A; protein kinase A alpha; protein kinase A catalytic subunit; protein kinase C beta; protein kinase C beta I; protein kinase C beta II; protein kinase C beta type; protein kinase C beta-II; protein kinase C gamma; protein kinase C gamma type; protein kinase C type I (gamma type); protein kinase C, beta; protein kinase C, beta 1; protein kinase C, beta 1 polypeptide; protein kinase C, gamma; protein kinase cAMP-activated catalytic subunit alpha; protein kinase, cAMP dependent, catalytic, alpha; protein kinase, cAMP-dependent, alpha catalytic subunit; protein kinase, cAMP-dependent, catalytic, alpha; RATPKCI; SCA14; sperm cAMP-dependent protein kinase catalytic subunit