CAB39 Recombinant Rabbit Monoclonal Antibody (24GB6950) | Invitrogen MA5-56996 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CAB39 Recombinant Rabbit Monoclonal Antibody (24GB6950)

catalog :

MA5-56996

quantity :

20 uL

price :

US 139.00

clonality :

recombinant

host :

domestic rabbit

conjugate :

nonconjugated

clone name :

24GB6950

reactivity :

human, mouse, rat

application :

western blot

product information

Product Type :

Antibody

Product Name :

CAB39 Recombinant Rabbit Monoclonal Antibody (24GB6950)

Catalog # :

MA5-56996

Quantity :

20 uL

Price :

US 139.00

Clonality :

Recombinant Monoclonal

Purity :

Affinity chromatography

Host :

Rabbit

Reactivity :

Human, Mouse, Rat

Applications :

Western Blot: 1:1,000-1:5,000

Species :

Human, Mouse, Rat

Clone :

24GB6950

Isotype :

IgG

Storage :

-20 C

Description :

Peutz-Jeghers Syndrome (PJS) is a rare hereditary disease characterized by melanocytic macules of the lips, gastrointestinal hamartomatous polyps and an increased risk for many classes of cancer. The serine/threonine kinase LKB1 (also designated STK11) has been identified as the gene mutated in PJS. LKB1 activity increases upon the binding of a regulatory complex consisting of the STE20-related adaptor-alpha (STRAD alpha) pseudo kinase and the calcium binding protein 39 (MO25 alpha). STRAD and MO25 determine the subcellular localization of LKB1 by initiating its translocation from the nucleus to the cytoplasm, thus regulating the tumor suppressor activity of LKB1. The LKB1/STRAD/MO25 complex acts as an AMP-activated protein kinase kinase (AMPKK).

Immunogen :

A synthesized peptide derived from human CAB39/MO25 (aa 323-341)

Format :

Liquid

Applications w/Dilutions :

Western Blot: 1:1,000-1:5,000

Aliases :

AA408805; AA960512; C78372; Cab39; calcium binding protein 39; calcium binding protein, 39 kDa; calcium-binding protein 39; CGI-66; MO25; MO25alpha; Protein Mo25