HSD3B1/HSD3B2 Recombinant Rabbit Monoclonal Antibody (HL2307) | Invitrogen MA5-56747 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

HSD3B1/HSD3B2 Recombinant Rabbit Monoclonal Antibody (HL2307)

catalog :

MA5-56747

quantity :

100 uL

price :

US 479.00

clonality :

recombinant

host :

domestic rabbit

conjugate :

nonconjugated

clone name :

HL2307

reactivity :

human, mouse

application :

western blot

product information

Product Type :

Antibody

Product Name :

HSD3B1/HSD3B2 Recombinant Rabbit Monoclonal Antibody (HL2307)

Catalog # :

MA5-56747

Quantity :

100 uL

Price :

US 479.00

Clonality :

Recombinant Monoclonal

Purity :

protein A

Host :

Rabbit

Reactivity :

Human, Mouse

Applications :

Western Blot: Assay-dependent

Species :

Human, Mouse

Clone :

HL2307

Isotype :

IgG

Storage :

-20 C, Avoid Freeze/Thaw Cycles

Description :

HSD3B1 and HSD3B2 (Hydroxy-Delta-5-Steroid Dehydrogenase, 3 Beta- and Steroid Delta-Isomerase 1 and 2) are genes that encode enzymes crucial for the biosynthesis of all classes of hormonal steroids, including glucocorticoids, mineralocorticoids, androgens, and estrogens. These enzymes catalyze the conversion of delta-5-3-beta-hydroxysteroids into delta-4-3-ketosteroids, a key step in the steroidogenesis pathway. HSD3B1 is predominantly expressed in the placenta and peripheral tissues, while HSD3B2 is mainly found in the adrenal glands and gonads. Mutations or dysregulation in these genes can lead to various disorders, such as congenital adrenal hyperplasia, which affects steroid hormone production and can result in a range of clinical symptoms from salt-wasting crises to ambiguous genitalia. Given their fundamental role in steroid metabolism, HSD3B1 and HSD3B2 are important targets for understanding and treating endocrine disorders and diseases related to steroid hormone imbalance.

Immunogen :

Recombinant fragment of human HSD3B2

Format :

Liquid

Applications w/Dilutions :

Western Blot: Assay-dependent