RANGAP1 Monoclonal Antibody (K52049_6F3) | Invitrogen MA5-56334 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

RANGAP1 Monoclonal Antibody (K52049_6F3)

catalog :

MA5-56334

quantity :

200 ug

price :

US 839.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

K52049_6F3

reactivity :

human

application :

western blot, immunohistochemistry, immunoprecipitation, immunohistochemistry - paraffin section

product information

Product Type :

Antibody

Product Name :

RANGAP1 Monoclonal Antibody (K52049_6F3)

Catalog # :

MA5-56334

Quantity :

200 ug

Price :

US 839.00

Clonality :

Monoclonal

Purity :

protein A

Host :

Mouse

Reactivity :

Human

Applications :

Immunohistochemistry (Paraffin): 1:1,000, Immunoprecipitation: 1:100, Western Blot: 1:1,000

Species :

Human

Clone :

K52049_6F3

Isotype :

IgG1

Storage :

Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.

Description :

Ran is a small signaling GTPase that is involved in nucleocytoplasmic transport. Two additional functions of animal Ran in the formation of spindle asters and the reassembly of the nuclear envelope in mitotic cells have been recently reported. In contrast to Ras or Rho, Ran is not associated with membranes. Instead, the spatial sequestering of its accessory proteins, the Ran GTPase-activating protein RanGAP and the nucleotide exchange factor RCC1, appears to define the local concentration of RanGTP vs. RanGDP involved in signaling. Mammalian RanGAP is bound to the nuclear pore by a mechanism involving the attachment of small ubiquitin-related modifier protein (SUMO) to its C terminus and the subsequent binding of the SUMOylated domain to the nucleoporin Nup358.

Immunogen :

Recombinant human RANGAP1 (immunogen range is 251-370).

Format :

Liquid

Applications w/Dilutions :

Immunohistochemistry (Paraffin): 1:1,000, Immunoprecipitation: 1:100, Western Blot: 1:1,000

Aliases :

C79654; fug1; KIAA1835; MGC20266; mKIAA1835; RAN GTPase activating protein 1; RAN GTPase activating protein 1 a; Ran GTPase activating protein 1 b; Ran GTPase activating protein 1 L homeolog; Ran GTPase activating protein 1 S homeolog; ran GTPase-activating protein 1; RANGAP; RanGAP1; rangap1.L; rangap1.S; rangap1a; rangap1-a; rangap1b; rangap1-b; rna1p; SD; segregation distorter homolog; segregation distortion; XELAEV_18023679mg; XELAEV_18025680mg