ZFP36 Monoclonal Antibody (K94030_2F8) | Invitrogen MA5-56085 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

ZFP36 Monoclonal Antibody (K94030_2F8)

catalog :

MA5-56085

quantity :

200 ug

price :

US 809.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

K94030_2F8

reactivity :

human

application :

western blot, immunoprecipitation

product information

Product Type :

Antibody

Product Name :

ZFP36 Monoclonal Antibody (K94030_2F8)

Catalog # :

MA5-56085

Quantity :

200 ug

Price :

US 809.00

Clonality :

Monoclonal

Purity :

protein A

Host :

Mouse

Reactivity :

Human

Applications :

Immunoprecipitation: 1:100, Western Blot: 1:1,000

Species :

Human

Clone :

K94030_2F8

Isotype :

IgG2a

Storage :

Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.

Description :

ZFP36 is a probable regulatory protein with a novel zinc finger structure involved in regulating the response to growth factors. Knockdown of ZFP36 increased both cognate macrophage gene mRNAs and inflammatory tumor necrosis factor protein release. Overexpression of ZFP36 resulted in decreased levels of the same genes supporting its role in regulating macrophage gene expression. Multiple phosphorylation sites in ZFP36 in mammalian cells were reported. ZFP36 can be phosphorylated by JNK as well as by the other members of the greater MAP kinase family. Gene expression profiling predicts clinical outcome of prostate cancer. Inappropriate ZFP36 production may be one factor that contributes to higher rheumatoid arthritis disease activity.

Immunogen :

Recombinant human ZFP36 (immunogen range is 171-310).

Format :

Liquid

Applications w/Dilutions :

Immunoprecipitation: 1:100, Western Blot: 1:1,000

Aliases :

G0/G1 switch regulatory protein 24; G0S24; GOS24; growth factor-inducible nuclear protein NUP475; mRNA decay activator protein ZFP36; Nup475; RNF162A; Tax interacting protein; TIS11; TIS11A; TIS11D; TISII; TNF alpha inhibitor; TPA-induced sequence 11; Tristetraprolin; tristetraprolin; LOW QUALITY PROTEIN: mRNA decay activator protein ZFP36; tristetraproline; TTP; Zfp36; zfp-36; ZFP36 ring finger protein; zinc finger protein 36; zinc finger protein 36 homolog; zinc finger protein 36, C3H type, homolog; zinc finger protein, C3H type, 36 homolog