SOAT1 Recombinant Rabbit Monoclonal Antibody (8J8E6) | Invitrogen MA5-55558 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

SOAT1 Recombinant Rabbit Monoclonal Antibody (8J8E6)

catalog :

MA5-55558

quantity :

100 uL

price :

US 419.00

clonality :

recombinant

host :

domestic rabbit

conjugate :

nonconjugated

clone name :

8J8E6

reactivity :

human

application :

western blot, ELISA

product information

Product Type :

Antibody

Product Name :

SOAT1 Recombinant Rabbit Monoclonal Antibody (8J8E6)

Catalog # :

MA5-55558

Quantity :

100 uL

Price :

US 419.00

Clonality :

Recombinant Monoclonal

Purity :

protein A

Host :

Rabbit

Reactivity :

Human

Applications :

ELISA: 1 ug/mL, Western Blot: 1:500-1:1,000

Species :

Human

Clone :

8J8E6

Isotype :

IgG

Storage :

-20 C, Avoid Freeze/Thaw Cycles

Description :

SOAT1 (sterol O-acyltransferase-1), also designated ACAT1, is a homotetra-meric enzyme that catalyzes the formation of cholesterol esters from cholesterol and long chain fatty acyl-coenzyme A (acyl-CoA). The gene encoding human SOAT1 maps to chromosome 1 and is expressed as a protein that localizes to the endoplasmic reticulum (ER) in several tissues, including liver, kidney, adrenal glands and macrophages. SOAT1 is involved in cellular cholesterol homeostasis as well as in foam cell formation and the subsequent progression of atherosclerosis. Several SOAT inhibitors have been developed for the treatment of atherosclerosis. SOAT2 (sterol O-acyltransferase-2), also known as ACAT2 (acyl-CoA:cholesterol acyltransferase-2), participates in lipo-protein assembly, catalyzing cholesterol esterification in mammalian cells. SOAT2 is an integral membrane protein that localizes to the endoplasmic reticulum of human intestinal cells. SOAT2 deficiency contributes to severe mental retardation and hypotonus.

Immunogen :

Recombinant fusion protein containing a sequence corresponding to amino acids 1-104 of human SOAT1.

Format :

Liquid

Applications w/Dilutions :

ELISA: 1 ug/mL, Western Blot: 1:500-1:1,000

Aliases :

8430426K15Rik; Acact; ACACT1; Acat; ACAT1; ACAT-1; acyl coenzyme A:cholesterol acyltransferase 1; acyl-coenzyme A:cholesterol acyltransferase 1; adrenocortical lipid depletion; ald; AW550831; cholesterol acyltransferase 1; hid; SOAT; SOAT1; STAT; sterol O-acyltransferase (acyl-Coenzyme A: cholesterol acyltransferase) 1; sterol O-acyltransferase 1