Phospho-PKC alpha/beta-2 (Thr638, Thr641) Recombinant Rabbit Monoclonal Antibody (8D8L5)

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

Phospho-PKC alpha/beta-2 (Thr638, Thr641) Recombinant Rabbit Monoclonal Antibody (8D8L5)

catalog :

MA5-55521

quantity :

100 uL

price :

US 419.00

clonality :

recombinant

host :

domestic rabbit

conjugate :

nonconjugated

clone name :

8D8L5

reactivity :

human

application :

western blot, ELISA

product information

Product Type :

Antibody

Product Name :

Phospho-PKC alpha/beta-2 (Thr638, Thr641) Recombinant Rabbit Monoclonal Antibody (8D8L5)

Catalog # :

MA5-55521

Quantity :

100 uL

Price :

US 419.00

Clonality :

Recombinant Monoclonal

Purity :

protein A

Host :

Rabbit

Reactivity :

Human

Applications :

ELISA: 1 ug/mL, Western Blot: 1:2,000-1:7,000

Species :

Human

Clone :

8D8L5

Isotype :

IgG

Storage :

-20 C, Avoid Freeze/Thaw Cycles

Description :

Protein Kinase c alpha (PKC alpha) is an 77 kDa member of the conventional group (cPKCs: sensitive to calcium, diacylglycerol, phosphatidylserine and phorbol esters) of the PKC family of serine/ threonine kinases that are involved in a wide range of physiological processes including mitogenesis, cell survival and transcriptional regulation. PKC alpha is an ubiquitously expressed PKC isozyme that has been implicated in the regulation of a broad range of cellular functions including proliferation, differentiation, development, migration, cell cell adhesion, cell extracellular matrix adhesion, and solute transport. The activation loop threonine (threonine 497 in PKC alpha) of conventional PKCs is phosphorylated by phosphoinositide dependent kinase 1 (PDK1). This phosphorylation is necessary for the autophosphorylation of threonine 638 in the carboxy terminus of PKC alpha, a step that is critical for regulating the rate of PKC alpha dephosphorylation and inactivation.

Immunogen :

A synthetic phosphorylated peptide around T638 of human PRKCA.

Format :

Liquid

Applications w/Dilutions :

ELISA: 1 ug/mL, Western Blot: 1:2,000-1:7,000

Aliases :

A130082F03Rik; AAG6; aging-associated gene 6; AI875142; PKCA; PKC-A; PKC-alpha; Pkcb; PKC-B; PKC-beta; PRKACA; PRKC Pan; PRKCA; PRKCB; PRKCB1; Prkcb2; protein kinase C alpha; protein kinase C alpha type; protein kinase C beta; protein kinase C beta I; protein kinase C beta II; protein kinase C beta type; protein kinase C beta-II; protein kinase C, alpha; protein kinase C, beta; protein kinase C, beta 1; protein kinase C, beta 1 polypeptide; protein kinase c-alpha