TIM3 VHH-8His-Cys-tag Recombinant Alpaca Monoclonal Antibody (SAA1348)

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

TIM3 VHH-8His-Cys-tag Recombinant Alpaca Monoclonal Antibody (SAA1348)

catalog :

MA5-54490

quantity :

100 ug

price :

US 429.00

clonality :

recombinant

host :

alpaca

conjugate :

nonconjugated

clone name :

SAA1348

reactivity :

human

application :

flow cytometry

product information

Product Type :

Antibody

Product Name :

TIM3 VHH-8His-Cys-tag Recombinant Alpaca Monoclonal Antibody (SAA1348)

Catalog # :

MA5-54490

Quantity :

100 ug

Price :

US 429.00

Clonality :

Recombinant Monoclonal

Purity :

Metal-chelate chromatography

Host :

Alpaca

Reactivity :

Human

Applications :

ELISA: Assay-dependent, Flow Cytometry: Assay-dependent

Species :

Human

Clone :

SAA1348

Isotype :

VHH

Storage :

Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.

Description :

TIM3 (Hepatitis A virus cellular receptor 2, HAVCR2, T-cell immunoglobulin, mucin-dmain containing-3) is a 281 amino acid long, Type-1 Th1- specific cell surface glycoprotein expressed on terminally differentiated CD4+Th1 and CD8+Tc1 cells. TIM3 consists of an IgV-like domain, a mucin-like domain in the extracellular region, and a conserved Tyrosine phosphorylation motif in the cytoplasmic region. TIM3 is involved in macrophage activation and induction of autoimmune diseases. Further, TIM3 down-regulates aggressive Th1-mediated immune responses and facilitates in the development of immune tolerance. Pathological significance of TIM3 has been attributed to Experimental autoimmune encephalomyelitis (EAE), a Th-1 dependent autoimmune disease, and also enhances the severity of experimental autoimmune encephalomyelitis in mice.

Immunogen :

Recombinant Human CD366/HAVCR2/TIM-3.

Format :

Liquid

Applications w/Dilutions :

ELISA: Assay-dependent, Flow Cytometry: Assay-dependent

Aliases :

CD366; FLJ14428; Havcr2; HAVcr-2; Hepatitis A virus cellular receptor 2; hepatitis A virus cellular receptor 2 homolog; kidney injury molecule-3; KIM-3; sCD366; soluble CD366; soluble TIM 3; T cell immunoglobulin mucin 3; T cell immunoglobulin mucin-3; T-cell immunoglobulin and mucin domain containing 3; T-cell immunoglobulin and mucin domain-containing protein 3; T-cell immunoglobulin mucin family member 3; T-cell immunoglobulin mucin receptor 3; T-cell membrane protein 3; Tim3; TIM-3; TIMD3; TIMD-3