CD16b VHH-8His-Cys-tag Recombinant Alpaca Monoclonal Antibody (C28)

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CD16b VHH-8His-Cys-tag Recombinant Alpaca Monoclonal Antibody (C28)

catalog :

MA5-54448

quantity :

100 ug

price :

US 429.00

clonality :

recombinant

host :

alpaca

conjugate :

nonconjugated

clone name :

C28

reactivity :

human

product information

Product Type :

Antibody

Product Name :

CD16b VHH-8His-Cys-tag Recombinant Alpaca Monoclonal Antibody (C28)

Catalog # :

MA5-54448

Quantity :

100 ug

Price :

US 429.00

Clonality :

Recombinant Monoclonal

Purity :

Metal-chelate chromatography

Host :

Alpaca

Reactivity :

Human

Applications :

ELISA: Assay-dependent, Functional Assay: Assay-dependent

Species :

Human

Clone :

C28

Isotype :

VHH

Storage :

Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.

Description :

CD16 (FCGR3A) is a 50-65 kDa cell surface molecule that exists in two forms - a transmembranous form expressed by NK cells and some T cells, and a phosphatidylinositol linked form expressed by granulocytes. CD16 is a low affinity receptor for IgG (FcR III), and is an important receptor mediating ADCC by NK cells. Human CD16 is expressed in two forms – FCGR3A and FCGR3B. FCGR3A is associated with the FcepsilonRI-gamma subunit and is responsible for antibody-dependent NK cell cytotoxicity. Mast cell FCGR3A is associated, with FcepsilonRI-beta subunit. Besides IgG, FCGR3A can be triggered also by oligomeric IgE. FCGR3B is a GPI-linked monomeric receptor expressed on neutrophils and is involved in their activation and induction of a pro-adhesive phenotype. Diseases associated with CD16 dysfunction include immunodeficiency 20 and systemic lupus erythematosus.

Immunogen :

Recombinant Human CD16b/FCGR3B.

Format :

Liquid

Applications w/Dilutions :

ELISA: Assay-dependent, Functional Assay: Assay-dependent

Aliases :

CD16; CD16B; Fc fragment of IgG receptor IIIb; Fc fragment of IgG, low affinity IIIb, receptor (CD16b); Fc gamma receptor IIIb; FCG3; Fc-gamma receptor IIIb (CD 16); Fc-gamma RIII; fc-gamma RIIIb; Fc-gamma RIII-beta; FCGR3; FCGR3B; FcR-10; FCRIII; FCRIIIb; IGFR3; IgG Fc receptor III-1; low affinity immunoglobulin gamma Fc region receptor III-B