This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
Complement C5 VHH-8His-Cys-tag Recombinant Alpaca Monoclonal Antibody (SAA1365)
catalog :
MA5-54411
quantity :
100 ug
price :
US 429.00
clonality :
recombinant
host :
alpaca
conjugate :
nonconjugated
clone name :
SAA1365
reactivity :
human
application :
immunocytochemistry
product information
Product Type :
Antibody
Product Name :
Complement C5 VHH-8His-Cys-tag Recombinant Alpaca Monoclonal Antibody (SAA1365)
Catalog # :
MA5-54411
Quantity :
100 ug
Price :
US 429.00
Clonality :
Recombinant Monoclonal
Purity :
Metal-chelate chromatography
Host :
Alpaca
Reactivity :
Human
Applications :
ELISA: Assay-dependent, Immunocytochemistry: Assay-dependent
Species :
Human
Clone :
SAA1365
Isotype :
VHH
Storage :
Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.
Description :
C5 (Complement C5) is a Protein Coding gene. Diseases associated with C5 include Complement Component 5 Deficiency and Eculizumab, Poor Response To. Among its related pathways are GPCR downstream signalling and Acquired partial lipodystrophy / Barraquer-Simons syndrome. Gene Ontology (GO) annotations related to this gene include signaling receptor binding and endopeptidase inhibitor activity. An important paralog of this gene is C3. This gene encodes a component of the complement system, a part of the innate immune system that plays an important role in inflammation, host homeostasis, and host defense against pathogens. The encoded preproprotein is proteolytically processed to generate multiple protein products, including the C5 alpha chain, C5 beta chain, C5a anaphylatoxin and C5b. The C5 protein is comprised of the C5 alpha and beta chains, which are linked by a disulfide bridge. Cleavage of the alpha chain by a convertase enzyme results in the formation of the C5a anaphylatoxin, which possesses potent spasmogenic and chemotactic activity, and the C5b macromolecular cleavage product, a subunit of the membrane attack complex (MAC). Mutations in this gene cause complement component 5 deficiency, a disease characterized by recurrent bacterial infections. Alternative splicing results in multiple transcript variants.
Immunogen :
Recombinant Human C5.
Format :
Liquid
Applications w/Dilutions :
ELISA: Assay-dependent, Immunocytochemistry: Assay-dependent
Aliases :
anaphylatoxin; anaphylatoxin C5; anaphylatoxin C5a analog; C3 and PZP-like alpha-2-macroglobulin domain-containing protein 4; C5; C5a; C5a anaphylatoxin; C5b; C5D; Complement C5; Complement C5 alpha chain; Complement C5 alpha' chain; Complement C5 beta chain; complement component 5; CPAMD4; ECLZB; Hc; He; hemolytic complement; prepro-C5; RGD1561905
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com81 Wyman Street
Waltham, MA USA 02451
800-678-5599
headquarters: USA
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